Results 21 to 30 of about 202,290 (315)

Levels of Soluble Interleukin 6 Receptor and Asp358Ala Are Associated With Cognitive Performance and Alzheimer Disease Biomarkers. [PDF]

Neurol Neuroimmunol Neuroinflamm, 2023
Quillen D, Hughes TM, Craft S, Howard T, Register T, Suerken C, Hawkins GA, Milligan C.   +7 more
europepmc   +3 more sources

Experience in using the assessment of the level of soluble interleukin-6 receptor in the process of rehabilitation of patients according to the program of aerobic training

Клинический разбор в общей медицине
Aim. Demonstration of the validity of assessing the level of soluble interleukin-6 receptor (s-IL-6R) in the process of recovery of patients according to the program of aerobic physical activity (APF) after the virus and bacterial pneumonia.
Andrey Yu. Tretyakov, Alexandra V. Zhabskaya, Alexandra V. Zhabskaya, Oleg V. Yermilov, Oleg V. Yermilov, Petr K. Alferov, Petr K. Alferov, Mikhail A. Tretyakov, Mikhail A. Tretyakov, Valeria V. Soloshenko, Valeria V. Soloshenko, Olga G. Deeva, Olga G. Deeva   +12 more
doaj   +2 more sources

Interleukin-6 receptor polymorphism is prevalent in HIV-negative Castleman Disease and is associated with increased soluble interleukin-6 receptor levels. [PDF]

PLoS ONE, 2013
Multicentric Castleman Disease is largely driven by increased signaling in the pathway for the plasma cell growth factor interleukin-6. We hypothesized that interleukin-6/interleukin-6 receptor/gp130 polymorphisms contribute to increased interleukin-6 ...
Katie Stone, Emily Woods, Susann M Szmania, Owen W Stephens, Tarun K Garg, Bart Barlogie, John D Shaughnessy, Brett Hall, Manjula Reddy, Antje Hoering, Emily Hansen, Frits van Rhee   +11 more
doaj   +2 more sources

Admixture Mapping of an Allele Affecting Interleukin 6 Soluble Receptor and Interleukin 6 Levels [PDF]

The American Journal of Human Genetics, 2007
Circulating levels of inflammatory markers can predict cardiovascular disease risk. To identify genes influencing the levels of these markers, we genotyped 1,343 single-nucleotide polymorphisms (SNPs) in 1,184 African Americans from the Health, Aging and Body Composition (Health ABC) Study. Using admixture mapping, we found a significant association of
David Reich, Nick Patterson, Vijaya Ramesh, Philip L. De Jager, Gavin J. McDonald, Arti Tandon, Edwin Choy, Donglei Hu, Bani Tamraz, Ludmila Pawlikowska, Christina Wassel-Fyr, Scott Huntsman, Alicja Waliszewska, Elizabeth J. Rossin, Rongling Li, Melissa Garcia, Alex P. Reiner, Robert E. Ferrell, Steve Cummings, Pui–Yan Kwok, Tamara Harris, Joseph M. Zmuda, Elad Ziv   +22 more
openalex   +3 more sources

Serum levels of interleukin-6 type cytokines and soluble interleukin-6 receptor in patients with rheumatoid arthritis [PDF]

Mediators of Inflammation, 1998
We investigated the serum concentrations of interleukin-6 (IL-6) and two IL-6 family of cytokines (leukaemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) as well as IL-6 soluble receptor (sIL-6R) using an enzyme-linked immunosorbent ...
T. Robak, A. Gladalska, H. Stepień, E. Robak   +3 more
doaj   +2 more sources

Circulating Levels of Interleukin-6 and Soluble Interleukin-6 Receptor in Acute Asthma [PDF]

Tuberculosis and Respiratory Diseases, 2000
Background : The recognition of bronchial asthma as an inflammatory disease led to the search for soluble markers that would be useful in assessing airway inflammation. Interleukin-6 (IL-6) is a representative proinflammatory cytokine that has been shown to be connected with various inflammatory diseases.
Kyoung Hoon Lee, Yong Chul Lee, Ki Tae Cheon, Heung Bum Lee, Yang Keun Rhee   +4 more
openalex   +2 more sources

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6. [PDF]

Journal of Experimental Medicine, 1996
Interleukin 6 (IL-6) is considered an important mediator of acute inflammatory responses. Moreover, IL-6 functions as a differentiation and growth factor of hematopoietic precursor cells, B cells, T cells, keratinocytes, neuronal cells, osteoclasts, and ...
Matthew Peters, Samuel A. Jacobs, Marc Ehlers, Petra Vollmer, Jürgen Müllberg, Eckhard Wolf, Г. Брем, K. H. Meyer zum Büschenfelde, Stefan Rose‐John   +8 more
openalex   +2 more sources

Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection [PDF]

Frontiers in Immunology
IntroductionSerum levels of interleukin-6 (IL-6) are increased in COVID-19 patients. IL-6 is an effective therapeutic target in inflammatory diseases and tocilizumab, a monoclonal antibody that blocks signaling via the IL-6 receptor (IL-6R), is used to ...
Juliane Lokau, Juliane Lokau, Yvonne Garbers, Manuel M. Vicente, Anna Dittrich, Stefan Meltendorf, Holger Lingel, Anja K. Münster-Kühnel, Monika Brunner-Weinzierl, Christoph Garbers, Christoph Garbers   +10 more
doaj   +2 more sources

Tocilizumab and soluble interleukin-6 receptor in JAK2V617F somatic mutation and myeloproliferative neoplasm [PDF]

EClinicalMedicine, 2020
Kasper Mønsted Pedersen, Yunus Çolak, Hans Carl Hasselbalch, Stig Egil Bojesen, Børge Grønne Nordestgaard   +4 more
doaj   +2 more sources

The soluble Interleukin 6 receptor: Generation and role in inflammation and cancer

European Journal of Cell Biology, 2011
Soluble cytokine receptors are frequently found in human serum, most of them possessing antagonistic properties. The Interleukin 6 receptor (IL-6R) is found as a transmembrane protein on hepatocytes and subsets of leukocytes, but soluble isoforms of the IL-6R (sIL-6R) are generated by alternative splicing or by limited proteolysis of the ADisintegrin ...
Athena, Chalaris, Christoph, Garbers, Björn, Rabe, Stefan, Rose-John, Jürgen, Scheller   +4 more
openaire   +3 more sources