Results 21 to 30 of about 134,028 (256)
Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils
Background: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal ...
E. Jablonska, M. Marcinczyk
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Modification of Soluble Immunological Parameters during Treatment with Interleukin-2
In the present study we tested numerous soluble immunological parameters (soluble Interleukin 2 receptor, Beta 2 microglobulin, Neopterin, soluble CD8 antigen, gamma Interferon and alpha Tumor Necrosis Factor) in sera obtained from 18 advanced cancer ...
I. Abbate +6 more
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Objective: To assess the association between genetic variants of transferrin receptor 2 (TFR2) exon 4 and anemia status and to describe the expression levels of several cytokines, hepcidin, soluble transferrin receptor and erythropoietin.
Dono Indarto +7 more
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Blood cytokine levels in patients with alcohol dependence during early withdrawal treatment
Objectives: Alcohol is known to modulate the immune system, which is associated with the pathophysiology of alcohol dependence (AD). Interleukin-6 (IL-6), soluble IL-6 receptor (sIL-6R), and tumor necrosis factor-alpha (TNF-α) are widely studied immune ...
Shu-Hao Hsu +5 more
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Soluble Human Interleukin‐6 Receptor [PDF]
The extracellular domain of the human interleukin‐6 (IL‐6) receptor, comprising 339 amino acids following the signal peptide, has been expressed in baculovirus‐infected insect cells (Sf158). When the soluble receptor secreted into the culture medium was purified by affinity chromatography, using IL‐6 immobilized on Sepharose, 6 mg soluble receptor was ...
Oliver Weiergräber +10 more
openaire +2 more sources
Background Rheumatoid arthritis is a risk factor for early mortality due to cardiovascular disease. Interleukin-33 appears to protect against the development of atherosclerosis.
Maria Raquel Costa Pinto +6 more
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Cytokine soluble receptors in perinatal and early neonatal life
Background: In contrast to cellular receptors, soluble receptors do not enhance the cellular activation because they do not have transmembranic and cytoplasmic parts, acting thereby as endogenous regulatory mechanisms against systemic functions of ...
Efthimia Protonotariou +5 more
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We investigated the serum concentrations of interleukin-6 (IL-6) and two IL-6 family of cytokines (leukaemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) as well as IL-6 soluble receptor (sIL-6R) using an enzyme-linked immunosorbent ...
T. Robak +3 more
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Soluble interleukin-6 receptor levels in pleural effusions
Generation of soluble cytokine receptors is a general phenomenon, and the roles of several such receptors have been investigated in clinical settings. Unlike other soluble cytokine receptors, soluble interleukin-6 receptor (sIL-6R) can act as an agonist and thus is implicated as an important modulator in the acute-phase reaction of prolonged ...
Yokoyama, A. +5 more
openaire +2 more sources
Patients with anaplastic lymphoma kinase-positive anaplastic large cell lymphoma often present with B-symptoms or hemophagocytosis and generate an anti-tumor immune response.
Fabian Knörr +6 more
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