Soluble Interleukin-6 Receptor Regulates Interleukin-6-Dependent Vascular Remodeling in Long-Distance Runners [PDF]
Frontiers in Physiology, 2021 Little is known about the effects of training load on exercise-induced plasma increase of interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) and their relationship with vascular remodeling.
Paulina Villar-Fincheira +15 more
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Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome [PDF]
Cell Reports Medicine, 2021 Summary: Data suggest that interleukin (IL)-6 blockade could reduce mortality in severe COVID-19, yet IL-6 is only modestly elevated in most patients. Chen et al.
Luke Y.C. Chen +5 more
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Serum level of soluble interleukin 6 receptor is a useful biomarker for identification of treatment‐resistant major depressive disorder [PDF]
Neuropsychopharmacology Reports, 2020 Aim A substantial proportion of major depressive disorder patients are treatment‐resistant to antidepressant therapy, who require augmentation drugs, or other treatments including electroconvulsive therapy or transcranial magnetic stimulation ...
Katsuhiko Yamasaki +2 more
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Soluble interleukin‐6 receptor in young adults and its relationship with body composition and autonomic nervous system [PDF]
Physiological Reports, 2019 Background The immune system generates inflammatory responses through cytokines like Interleukin 6 (IL‐6) and the Tumor Necrosis Factor alpha (TNF α); these cytokines mediate cellular responses aided by the presence of soluble receptors such as: Soluble ...
Henry H. León‐Ariza +3 more
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Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection [PDF]
Frontiers in ImmunologyIntroductionSerum levels of interleukin-6 (IL-6) are increased in COVID-19 patients. IL-6 is an effective therapeutic target in inflammatory diseases and tocilizumab, a monoclonal antibody that blocks signaling via the IL-6 receptor (IL-6R), is used to ...
Juliane Lokau +10 more
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Tocilizumab and soluble interleukin-6 receptor in JAK2V617F somatic mutation and myeloproliferative neoplasm [PDF]
EClinicalMedicine, 2020 Kasper Mønsted Pedersen +4 more
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Soluble interleukin-6 receptor in patients with JAK2V617F somatic mutation and myeloproliferative neoplasm [PDF]
EClinicalMedicine, 2020 Christoph Garbers, Stefan Rose-John
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Correlations between serum interleukin 6, serum soluble interleukin 6 receptor, and disease activity in systemic juvenile idiopathic arthritis patients treated with or without tocilizumab [PDF]
Central European Journal of Immunology, 2019 Soamarat Vilaiyuk +4 more
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Lack of knowledge: breast cancer and the soluble interleukin-6 receptor. [PDF]
Breast Care (Basel), 2010 Cytokines are and may be used as therapeutic targets in cancer therapy. In breast cancer, interleukin (IL)-6 is associated with different features of tumor biology like metastasis, certain stages, and decreased survival. It is now an established fact that signaling via the soluble IL-6 receptor (sIL-6R) («transsignaling») is an important process in the
Knüpfer H, Preiss R.
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Relationship of Soluble Interleukin-6 Receptors With Asthma: A Mendelian Randomization Study
Frontiers in Medicine, 2021 Purpose: Emerging evidence suggests a potential role of interleukin-6 pathways—trans-signaling with soluble interleukin-6 receptors—in the asthma pathobiology.
Yoshihiko Raita +9 more
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