Serum Soluble (Pro)Renin Receptor Levels in Maintenance Hemodialysis Patients. [PDF]
PLoS ONE, 2016 The (pro)renin receptor [(P)RR] is cleaved by furin to generate soluble (P)RR [s(P)RR], which reflects the status of the tissue renin-angiotensin system. Hemodialysis patients have advanced atherosclerosis.
Yoshifumi Amari +4 more
doaj +5 more sources
Soluble (pro)renin receptor as a novel laboratory biomarker of atherosclerosis [PDF]
Acta Biochimica et Biophysica SinicaLiu Chunju +10 more
doaj +4 more sources
Soluble (pro)renin receptor in elderly chronic heart failure patients
Frontiers in Bioscience-Landmark, 2020 Overactivation of renin-angiotensin system (RAS) is one of the main pathophysiological features in the evolution of chronic heart failure (CHF). The (pro)renin receptor ((P)RR) represents an important player in a tissue renin-angiotensin system (tissue ...
Danilo Obradovic +16 more
doaj +3 more sources
The role of (pro)renin receptor and its soluble form in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2023 The renin-angiotensin system (RAS) is a major classic therapeutic target for cardiovascular diseases. In addition to the circulating RAS, local tissue RAS has been identified in various tissues and plays roles in tissue inflammation and tissue fibrosis. (
Boyang Wang +9 more
doaj +3 more sources
Systemic factors related to soluble (pro)renin receptor in plasma of patients with proliferative diabetic retinopathy. [PDF]
PLoS ONE, 2017 (Pro)renin receptor [(P)RR], a new component of the tissue renin-angiotensin system (RAS), plays a crucial role in inflammation and angiogenesis in the eye, thus contributing to the development of proliferative diabetic retinopathy (PDR).
Keitaro Hase +4 more
doaj +2 more sources
Association between soluble (Pro)renin receptor concentration in cord blood and small for gestational age birth: a cross-sectional study. [PDF]
PLoS ONE, 2013 ObjectiveThe (pro)renin receptor [(P)RR] has been recognized as a multifunctional receptor. The purpose of this study was to assess the association between plasma soluble (P)RR [s(P)RR] concentration in human cord blood (i.e., neonatal blood at birth ...
Noriyoshi Watanabe +8 more
doaj +2 more sources
Soluble (Pro)Renin Receptor in Hypertension. [PDF]
Nephron, 2023 The (pro)renin receptor (PRR) was originally cloned as a specific single-transmembrane receptor for prorenin and renin and has now emerged as a multifunctional protein implicated in a wide variety of developmental and physiopathological processes.
Yang T.
europepmc +3 more sources
Increased Serum Soluble (Pro)renin Receptor Levels in Patients with Sarcopenia
International Journal of EndocrinologyPurpose. Sarcopenia is an advancing and widespread skeletal muscle condition characterized by the depletion of skeletal muscle mass. The (pro)renin receptor ((P)RR) is a multifaceted protein with both pathophysiological and physiological functions. (P)RR
Satoshi Morimoto +4 more
doaj +2 more sources
Potential of soluble (pro)renin receptor in kidney disease: can it go beyond a biomarker?
American Journal of Physiology - Renal Physiology, 2022 Tianxin Yang
exaly +2 more sources
Relationship between Soluble (pro)Renin Receptor and Renin Activity in Patients with Severe Heart Failure. [PDF]
J Clin Med, 2020 The (pro)renin receptor ((P)RR), which evokes renin activity with prorenin, is secreted extracellularly as soluble (P)RR (s(P)RR) and may participate in tissue renin-angiotensin system (RAS) activity in severe heart failure (HF) patients. The aim of this study was to determine whether s(P)RR is an adequate marker in severe HF patients treated with RAS ...
Ikeda Y +5 more
europepmc +4 more sources