Results 51 to 60 of about 6,500,973 (281)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Effect of boiling time on protein content, total soluble solids, and sensory quality of probiotic soy milk (Glycine max L.). [PDF]

open access: yes
This study aimed to analyze the effect of different boiling time on protein content, total soluble solids (TSS), and sensory characteristics, including taste and aroma, of probiotic soy milk (Glycine max L.).
Kusumaningtyas, Maharani   +3 more
core   +2 more sources

Postharvest Quality of ‘Keepsake’ Apple Fruit

open access: yesHortTechnology
Storage information regarding ‘Keepsake’ apple fruit is lacking. The objective of this research was to investigate the postharvest characteristics of ‘Keepsake’ apple (Malus ×domestica Borkh.), which is a parent of ‘Honeycrisp’. Apples were obtained from
Cindy Tong
doaj   +1 more source

Analysis for Soluble Solid Contents in Pineapples using NIR Spectroscopy

open access: yesJurnal Teknologi, 2014
This research investigates the use of predictive models and a low cost spectroscopy in non-invasive Soluble Solids Content (SSC) assessment. The challenge is to model complex and high-dimensional spectral data.  Results indicate that the SSC prediction of pineapples harvested on different days using the proposed approach is promising.
Abdul Rahim, Herlina   +2 more
openaire   +2 more sources

PREDICTION OF THE SOLUBLE SOLIDS CONTENT IN THREE FRUIT SPECIES USING NIRS APPROACH [PDF]

open access: yesAnais do XX Congresso Brasileiro de Engenharia Química, 2015
The fruit structure effect (passion fruit, tomato and apricot) was investigated on prediction performance of soluble solids content (SSC) using NIR spectroscopy. Relationships between spectral wavelengths and SSC data were evaluated through the application of chemometric techniques based on partial least squares (PLS).
G. A. OLIVEIRA   +3 more
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Soluble solids content (oBx) in acquired juices in relation to press type and the pretreatment method.

open access: yes, 2019
Soluble solids content (oBx) in acquired juices in relation to press type and the pretreatment method.
Leszek Rydzak (6996902)   +5 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

The effect of exercise on plasma soluble IL-6 receptor concentration: a dichotomous response [PDF]

open access: yes, 2010
The aim of this article is to review current literature on the response of soluble interleukin-6 receptor to exercise and identify a potential role for sIL-6R in skeletal muscle function.
Stevenson, Emma   +6 more
core  

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