Results 91 to 100 of about 115,117 (314)

A review of the use of somatostatin analogs in oncology

OncoTargets and Therapy, 2013
Somatostatin is a neuropeptide produced by paracrine cells that are located throughout the gastrointestinal tract, lung, and pancreas, and is also found in various locations of the nervous system.
O. Keskin, Ş. Yalçın
semanticscholar   +1 more source

Neural circuitry of rapid eye movement sleep homeostasis: Mechanistic insights and pathological implications

Sleep Research, EarlyView.
Abstract Rapid eye movement (REM) sleep is a unique brain state crucial for emotion, memory, and plasticity. Unlike well‐understood non‐REM (NREM) sleep homeostasis, REM sleep homeostasis remains less clearly defined. This review highlights recent progress in understanding REM sleep homeostasis, focusing on its neurophysiological markers, neural ...
Ting He
wiley   +1 more source

Somatostatin-receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors.

Endocrine-Related Cancer, 2010
Somatostatin receptor imaging (SRI) with [(111)In-DTPA(0)]octreotide has proven its role in the diagnosis and staging of gastroenteropancreatic neuroendocrine tumors (GEPNETs).
D. Kwekkeboom, B. Kam, M. van Essen, Jaap J. M. Teunissen, C. van Eijck, R. Valkema, M. de Jong, W. D. de Herder, E. Krenning   +8 more
semanticscholar   +1 more source

Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer

Small Science, EarlyView.
Nanogel refers to nanosized particles formed by physical or chemical crosslinking of polymers. Rational design and refinement of nanogel properties are imperative to unlock their full potential, ensuring tailored solutions for personalized cancer management. This review elucidates the transformative potential of radiolabeled nanogels in revolutionizing
Sanchita Ghosh, Weibo Cai, Rubel Chakravarty   +2 more
wiley   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Primary Structure of Somatostatin, A Hypothalamic Peptide That Inhibits the Secretion of Pituitary Growth Hormone [PDF]

, 1973
Roger Burgus, Nicholas Ling, Madalyn Butcher, Roger Guillemin   +3 more
openalex   +1 more source

Computerised Algorithms Showed Promise in Identifying Swedish Children With Atypical Growth Patterns

Acta Paediatrica, EarlyView.
ABSTRACT Aim We used computerised algorithms comparing the performance of the growth assessment criteria recommended in Sweden with those used in Finland and established by the International Obesity Task Force (IOTF). Methods Historical data from 3214 Swedish children (51.6% girls) at 4, 6, and 8 years of age were compared with five Finnish screening ...
Lars Gelander, Aimon Niklasson, Anton Holmgren, Aldina Pivodic, Antti Saari, Ulla Sankilampi, Leo Dunkel, Kerstin Albertsson‐Wikland   +7 more
wiley   +1 more source

Knocking Out SST Gene of BGC823 Gastric Cancer Cell by CRISPR/Cas9 Enhances Migration, Invasion and Expression of SEMA5A and KLF2

Cancer Management and Research, 2020
Wei Chen, 1 Ruixian Ding, 1 Jinlu Tang, 1 Haodong Li, 2 Chonghua Chen, 2 Yaru Zhang, 1 Qinxian Zhang, 1 Xiaoyan Zhu 1 1Department of Histology and Embryology, School of Basic Medical Sciences, Zhengzhou University, Henan, People’s Republic of ...
Chen W, Ding R, Tang J, Li H, Chen C, Zhang Y, Zhang Q, Zhu X   +7 more
doaj  

Somatostatin Release from Isolated Perfused Rat Pancreas: Possible Role of Endogenous Somatostatin on Insulin Release [PDF]

, 1979
Seizo Kadowaki, Tomohiko Taminato, Tsutomu Chiba, Kozaburo Mori, Hiromi Abe, Yasuo Goto, Yutaka Seino, Shigeru Matsukura, Masumi Nozawa, Takuo Fujita   +9 more
openalex   +1 more source

Radiolabeled somatostatin analog [177Lu-DOTA0,Tyr3]octreotate in patients with endocrine gastroenteropancreatic tumors.

Journal of Clinical Oncology, 2005
PURPOSE There are few treatment options for patients with metastasized or inoperable endocrine gastroenteropancreatic (GEP) tumors. Chemotherapy can be effective, but the response is usually less than 1 year.
D. Kwekkeboom, Jaap J. M. Teunissen, W. Bakker, P. Kooij, W. D. de Herder, R. Feelders, C. van Eijck, J. Esser, B. Kam, E. Krenning   +9 more
semanticscholar   +1 more source