Results 121 to 130 of about 76,426 (249)
Advanced Science, Volume 13, Issue 7, 3 February 2026.Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang +7 more
wiley +1 more source
Single‐cell analysis reveals neuroprotective histone deacetylase inhibitor pathways
Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.Abstract INTRODUCTION Alzheimer's disease (AD) involves β‐amyloid (Aβ) accumulation, tau pathology, and neuroinflammation, driving cognitive decline. Despite extensive research, disease‐modifying therapies remain elusive. We integrated single‐cell RNA sequencing (scRNA‐seq), spatial transcriptomics, and in vitro validation to identify repurposable ...
Madeline Peyton +12 more
wiley +1 more source
Somatostatin-Receptor Scintigraphy Identifies a Cardiac Pheochromocytoma [PDF]
, 1999 Yves Cottin +7 more
openalex +1 more source
CNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.Somatotroph tumors, a rare subtype of pituitary adenomas, can be histologically classified into sparsely granulated (SGSTs) and densely granulated somatotroph tumors (DGSTs) based on cytokeratin staining. SGSTs are generally more invasive and less responsive to medical therapy, making their early identification clinically important.
Le Chen +11 more
wiley +1 more source
From Struggling (With) Screening Tests to Mouse Models of Depression‐Relevant Neurobehavioral States
Current Protocols, Volume 6, Issue 2, February 2026.Abstract A major, serendipitous psychiatric discovery is monoamine‐transporter reuptake inhibition as an antidepressant mechanism of action. Chronic treatment with such antidepressants is efficacious, with onset requiring 1‐2 weeks, in many but by no means all patients with major depressive or another stress‐related neuropsychiatric disorder.
Christopher R. Pryce
wiley +1 more source
Laser &Photonics Reviews, Volume 20, Issue 3, 5 February 2026.A high‐speed, multi‐color light‐sheet microscope, named quad‐SPIM, enables rapid three dimensional (3D) imaging of large cleared human brain samples with simultaneous four‐channel acquisition. This custom‐built system achieves subcellular resolution across centimeter‐scale volumes, maintaining high image quality.
Laura Perego +11 more
wiley +1 more source
Somatostatin analogs: Future directions [PDF]
Metabolism, 1996 Lamberts, S. W.J. +3 more
openaire +2 more sources