Results 121 to 130 of about 128,394 (306)
Abstract Pancreatic neuroendocrine tumors (panNETs) are rare pediatric malignancies with age‐specific clinical and biological features. Data on their presentation, management, and outcomes remain limited. This retrospective study analyzed 28 pediatric panNET cases from the German Malignant Endocrine Tumor (MET) Registry enrolled between 1997 and 2024 ...
Katharina Karges+12 more
wiley +1 more source
The impact of re‐characterizing metastatic pancreatic neuroendocrine tumors: A prospective study
Abstract The biology of metastatic pancreatic neuroendocrine tumors (panNET) may alter over time. It remains to be defined if, how, and when this patient group should be recommended to re‐evaluate the characteristics of their disease. This prospective single‐center, longitudinal cohort study at Uppsala University Hospital, Sweden (NCT03130205 ...
Kazhan Mollazadegan+9 more
wiley +1 more source
Acromegaly: pathogenesis & treatment [PDF]
Acromegaly is a multi-system disorder whose etiology is most often traced back to a growth hormone-secreting pituitary adenoma (PA). Growth hormone (GH) secretion promotes insulin-like growth factor 1 (IGF-1) release from peripheral tissues, leading to ...
Tilvawala, Megha
core
Glucose Infusion Potentiates the Acute Insulin Response to Nonglucose Stimuli during the Infusion of Somatostatin* [PDF]
Gerald J. Taborsky+3 more
openalex +1 more source
Abstract Patients with gastroenteropancreatic–neuroendocrine tumors (GEP‐NETs) may present skeletal fragility that might be related to multiple factors, including bone metastases, vitamin D deficiency, hormone secretion, and disease treatments. This study examines the prevalence and determinants of fragility fractures in low grading (G1‐G2) GEP‐NETs ...
Alessandro Brunetti+15 more
wiley +1 more source
Immunohistochemical characterization of monolayer cell cultures of embryonic chicken pancreas and measurement of somatostatin release. [PDF]
Nicholas Barden+4 more
openalex +1 more source
Abstract Gastric, duodenal and rectal neuroendocrine tumours (NETs) are increasingly detected due to advances in endoscopic imaging. While international guidelines provide criteria for endoscopic management, several aspects remain controversial due to limited high‐quality evidence.
Francesco Panzuto+7 more
wiley +1 more source
Chromogranin A in the pancreatic islet [PDF]
Chromogranin A (CGA) is the major soluble protein within secretory vesicles of chromaffin cells. A polyclonal antiserum was raised against bovine CGA and characterized in two-dimensional immunoblots. Cellular and subcellular distribution of CGA in bovine
Aunis, D.+4 more
core
Inhibition by somatostatin of insulin release from isolated pancreatic islets [PDF]
Hiroshi Okamoto+4 more
openalex +1 more source
Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer+4 more
wiley +1 more source