Results 131 to 140 of about 76,426 (249)

Lifespan‐Extending Endogenous Metabolites

Aging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Intracellular degradation of somatostatin‐14 following somatostatin‐receptor 3‐mediated endocytosis in rat insulinoma cells [PDF]

, 2008
Dirk Roosterman, Nicole Brune, Oliver J. Kreuzer, M Feld, Sylvia Pauser, Kim Zarse, Martin Steinhoff, Wolfgang Meyerhof   +7 more
openalex   +1 more source

Metastatic Pheochromocytoma and Paraganglioma: Somatostatin Receptor 2 Expression, Genetics, and Therapeutic Responses [PDF]

, 2023
Alessa Fischer, Simon Kloos, Umberto Macciò, Juliane Friemel, Hanna Remde, Martin Faßnacht, Christina Pamporaki, Graeme Eisenhofer, Henri Timmers, Mercedes Robledo, Stephanie Fliedner, Katharina Wang, Julian Maurer, Astrid Reul, Kathrin Zitzmann, Nicole Bechmann, Gintare Žygienė, Susan Richter, Constanze Hantel, Diana Vetter, Kuno Lehmann, Hermine Mohr, Natalia S. Pellegata, Martin Ullrich, Jens Pietzsch, Christian G. Ziegler, Stefan R. Bornstein, Matthias Kroiß, Martín Reincke, Karel Pacák, Ashley Grossman, Felix Beuschlein, Svenja Nölting   +32 more
openalex   +1 more source

Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease

European Journal of Neuroscience, Volume 63, Issue 3, February 2026.
This review discusses our current understanding of the structure–function, expression and roles in neural circuits of the less studied glutamate delta 1 (GluD1) receptor. Converging data suggests many unique features of GluD1 including expression at both excitatory and inhibitory synapses and binding to D‐serine and GABA.
Diane Choi, Poojashree B. Chettiar, Yoland Smith, Shashank M. Dravid   +3 more
wiley   +1 more source

A dose-finding study of lanreotide (A somatostatin analog) in patients with colorectal carcinoma [PDF]

, 1996
Angelo Di Leo, Emilio Bajetta, Leonardo Ferrari, Laura Biganzoli, Luigi Mariani, Carlo Carnaghi, E Camerini, Roberto Buzzoni, Jean Marc Ruiz   +8 more
openalex   +1 more source

Somatostatin 1.1 contributes to the innate exploration of zebrafish larva [PDF]

, 2020
Feng B. Quan, Laura Desban, Olivier Mirat, Maxime Kermarquer, Julian Roussel, Fanny Koëth, Hugo Marnas, Lydia Djenoune, François‐Xavier Lejeune, Hervé Tostivint, Claire Wyart   +10 more
openalex   +1 more source

Astrocyte Regulation of Spinal Circuit Function

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Spinal cord astrocytes exist as an additional component of the computational framework that governs both sensory perceptions and motor outputs (left). By integrating local synaptic activity together with signals that reflect whole‐body state (e.g., neuromodulators, immune signals, and vascular signals) into defined input states (Sn), astrocytes adapt ...
Mary Kaye Duff, Min Jun Li, Axel Nimmerjahn   +2 more
wiley   +1 more source

Somatostatin Receptors in Human Meningiomas—Clinicopathological Aspects [PDF]

, 2021
Sofie Eline Tollefsen, Anders Hagen Jarmund, Borgny Ytterhus, Øyvind Salvesen, Patricia Mjønes, Sverre H. Torp   +5 more
openalex   +1 more source

Inhibitory GABAergic Neuron Loss due to Oxidative Damage During Ex Vivo Acute Brain Slice Preparation Influences Genesis and Dynamics of Epileptiform Activity

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Ex vivo brain slice preparation is a popular technique in neuroscience research with many variations in preparation method. We compared two popular variations in brain slice preparation and found that the choice of brain slice preparation technique significantly affects the viability of neuronal preparation.
Felix Chan, Anupam Hazra, Ashan Jayasekera, Katherine Huang, Shuna Whyte, Leolie Telford‐Cooke, Kamilah Lakhani, Xiaomeng Li, Rebecca Shields, Angeline Kosim, Darwin Su, Carol Murray, Mark O. Cunningham   +12 more
wiley   +1 more source

Determinants of incidence trends in pancreatic neuroendocrine neoplasms

Journal of Neuroendocrinology, Volume 38, Issue 2, Febuary 2026.
Abstract The incidence of pancreatic neuroendocrine neoplasms (NENs) is rising; whether this reflects a true increase in disease occurrence or improved detection remains uncertain. We conducted a retrospective, population‐based study using data from the Surveillance, Epidemiology, and End Results (SEER) Program (1975–2021) to examine temporal trends in
Giuseppe Lamberti, Elisa Andrini, Adriana Di Odoardo, Arianna Zappi, Claudio Ricci, Davide Campana   +5 more
wiley   +1 more source