The expanding role of nuclear medicine in therapeutic strategies [PDF]
The concept of carrying a cytotoxic radionuclide directly to cancerous cells is an attractive alternative to conventional forms of radiation treatment.
Aquilina, Mark Anthony
core
Primary Structure of Somatostatin, A Hypothalamic Peptide That Inhibits the Secretion of Pituitary Growth Hormone [PDF]
Roger Burgus+3 more
openalex +1 more source
Neurogenomic landscape associated with status‐dependent cooperative behaviour
Abstract The neurogenomic mechanisms mediating male–male reproductive cooperative behaviours remain unknown. We leveraged extensive transcriptomic and behavioural data on a neotropical bird species (Pipra filicauda) that performs cooperative courtship displays to understand these mechanisms.
Peri E. Bolton+6 more
wiley +1 more source
Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis. [PDF]
Elliott W. Chideckel+5 more
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The potential role of somatostatin (SRIF) in the diagnosis and treatment of nonendocrine human cancers is reviewed. There have been many reports of the growth-inhibitory activity of SRIF on normal and transformed cells in vitro. Many processes involved in malignant tumor growth depend on autocrine growth mechanisms, and somatostatin receptors (ssts ...
openaire +3 more sources
The human colon: Evidence for degenerative changes during aging and the physiological consequences
Reduced nociceptor innervation can explain diminished abdominal pain among the elderly. Degenerative changes occur within the colon wall, especially ascending colon. Mechanisms may include senescence‐like activity and inflammaging. Constipation is more likely to occur during age‐related challenges affecting functions of the bowel that now have reduced ...
Nicholas Baidoo, Gareth J. Sanger
wiley +1 more source
The Ontogenesis of Human Fetal Hormones. IV. Somatostatin, Luteinizing Hormone Releasing Factor, and Thyrotropin Releasing Factor in Hypothalamus and Cerebral Cortex of Human Fetuses 10-22 Weeks of Age [PDF]
Michel L. Aubert+2 more
openalex +1 more source
Abstract figure legend Somatostatin binds to a G‐protein‐coupled receptor to inhibit the release of catecholamine from chromaffin cells. This action has no impact on Ca2+ levels and is similar for Ca2+ entry through voltage‐gated Ca2 channels and for Ca2+ mobilization from the endoplasmic reticulum.
Jinbo Cheng, Meyer B. Jackson
wiley +1 more source
The effect of somatostatin on the response of GLI to the intraduodenal administration of glucose, protein, and fat [PDF]
Hideo Sakurai+2 more
openalex +1 more source
Abstract figure legend The incretin system in obesity. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) (yellow) and glucagon‐like peptide‐1 (GLP‐1) (blue) are produced by the proximal and distal small intestinal epithelium, where they are released postprandially into the bloodstream to modulate a myriad of physiological and ...
Constanza Alcaino+2 more
wiley +1 more source