Results 141 to 150 of about 68,999 (229)

Recurrence rates and risk factors in obscure gastrointestinal bleeding

open access: yesDEN Open, Volume 5, Issue 1, April 2025.
Abstract Obscure gastrointestinal bleeding (OGIB), defined in 2010, involves bleeding from the GI tract that remains unexplained after standard diagnostic procedures. OGIB, which accounts for about 5% of all GI bleeds, poses diagnostic and management challenges, particularly due to the anatomical features of the small intestine.
Sachiyo Onishi   +7 more
wiley   +1 more source

Somatostatin triggers local cAMP and Ca<sup>2+</sup> signaling in primary cilia to modulate pancreatic β-cell function. [PDF]

open access: yesEMBO J
Nilsson CI   +7 more
europepmc   +1 more source

Opiate antagonistic properties of an octapeptide somatostatin analog. [PDF]

open access: bronze, 1982
R. Maurer   +4 more
openalex   +1 more source

Profound gastric mucosal changes and severe rebound acid hypersecretion after long‐term Vonoprazan use: A case report

open access: yesDEN Open, Volume 5, Issue 1, April 2025.
Abstract Vonoprazan is a novel acid blocker with greater potency than proton pump inhibitors. A Japanese study reported no significant safety concerns over 5 years of Vonoprazan use; however, elevated serum gastrin and increased parietal cell and foveolar hyperplasia were observed, and long‐term safety data beyond 5 years are limited.
Hiroko Suda, Sachi Eto, Koichi Sakurai
wiley   +1 more source

Identification and Exploration of Immunity‐Related Genes and Natural Products for Alzheimer's Disease Based on Bioinformatics, Molecular Docking, and Molecular Dynamics

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 4, April 2025.
We used a variety of methods to identify biomarkers and compounds of Alzheimer's disease, providing new insights into the clinical research transformation of Alzheimer's disease. ABSTRACT Background Recent research highlights the immune system's role in AD pathogenesis and promising prospects of natural compounds in treatment.
Pengpeng Liang   +7 more
wiley   +1 more source

Activating Striatal Parvalbumin Interneurons to Alleviate Chemotherapy‐Induced Muscle Atrophy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Cisplatin is a widely used chemotherapeutic agent for treating solid tumours. Still, it induces severe side effects, including muscle atrophy. Understanding the mechanisms of cisplatin‐induced muscle loss and exploring potential therapeutic strategies are essential.
Jun Hu   +5 more
wiley   +1 more source

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