Recurrence rates and risk factors in obscure gastrointestinal bleeding
Abstract Obscure gastrointestinal bleeding (OGIB), defined in 2010, involves bleeding from the GI tract that remains unexplained after standard diagnostic procedures. OGIB, which accounts for about 5% of all GI bleeds, poses diagnostic and management challenges, particularly due to the anatomical features of the small intestine.
Sachiyo Onishi+7 more
wiley +1 more source
Somatostatin triggers local cAMP and Ca<sup>2+</sup> signaling in primary cilia to modulate pancreatic β-cell function. [PDF]
Nilsson CI+7 more
europepmc +1 more source
Opiate antagonistic properties of an octapeptide somatostatin analog. [PDF]
R. Maurer+4 more
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Abstract Vonoprazan is a novel acid blocker with greater potency than proton pump inhibitors. A Japanese study reported no significant safety concerns over 5 years of Vonoprazan use; however, elevated serum gastrin and increased parietal cell and foveolar hyperplasia were observed, and long‐term safety data beyond 5 years are limited.
Hiroko Suda, Sachi Eto, Koichi Sakurai
wiley +1 more source
Insight into the Potential of Somatostatin Vaccination with Goats as a Model: From a Perspective of the Gastrointestinal Microbiota. [PDF]
Zhang X+5 more
europepmc +1 more source
We used a variety of methods to identify biomarkers and compounds of Alzheimer's disease, providing new insights into the clinical research transformation of Alzheimer's disease. ABSTRACT Background Recent research highlights the immune system's role in AD pathogenesis and promising prospects of natural compounds in treatment.
Pengpeng Liang+7 more
wiley +1 more source
Molecular identification of somatostatin family in tilapia and the effect of food intake on pss2 and sstr3a. [PDF]
Cai R+5 more
europepmc +1 more source
Activating Striatal Parvalbumin Interneurons to Alleviate Chemotherapy‐Induced Muscle Atrophy
ABSTRACT Background Cisplatin is a widely used chemotherapeutic agent for treating solid tumours. Still, it induces severe side effects, including muscle atrophy. Understanding the mechanisms of cisplatin‐induced muscle loss and exploring potential therapeutic strategies are essential.
Jun Hu+5 more
wiley +1 more source
Real-time detection of somatostatin release from single islets reveals hypersecretion in type 2 diabetes. [PDF]
Yang M+5 more
europepmc +1 more source
The interaction of Vasoactive Intestinal Polypeptide (VIP), glucose and arginine on the secretion of insulin, glucagon and somatostatin in the perfused rat pancreas [PDF]
J Szecówka, Elvi Sandberg, S. Efendić
openalex +1 more source