Results 151 to 160 of about 179,431 (364)

Quality of life as a predictor for survival in patients with small intestinal neuroendocrine tumours

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Health‐related quality of life (HRQoL) has been shown to predict overall survival (OS) in several different malignancies, but not in patients with small intestinal neuroendocrine tumours (siNET). We evaluated the influence of HRQoL on survival in patients with siNET. We included 85 patients with advanced siNET who completed the validated HRQoL
Håkan Ohlsson   +4 more
wiley   +1 more source

Telotristat ethyl affects tumour‐fibroblast crosstalk in small intestinal neuroendocrine tumours

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract Small intestinal neuroendocrine tumours (SI‐NETs) are associated with mesenteric fibrosis, which causes significant morbidity and mortality. Telotristat ethyl was developed to treat carcinoid syndrome in SI‐NET patients. Recent studies indicated telotristat ethyl could have anti‐tumour activity; however, the mechanism remains unclear.
Harry Hodgetts   +7 more
wiley   +1 more source

Inhibition by somatostatin of insulin release from isolated pancreatic islets [PDF]

open access: bronze, 1975
Hiroshi Okamoto   +4 more
openalex   +1 more source

A male‐dominant cell group expressing calbindin‐D28K and androgen receptor in the mouse preoptic area requires postnatal testicular androgens and histone deacetylation

open access: yesJournal of Neuroendocrinology, EarlyView.
Abstract The mouse brain is masculinized by postnatal testicular androgens, which are active after conversion to estrogens and modulate gene expression epigenetically, at least in part. The preoptic area contains a sexually dimorphic nucleus (SDN) comprising calbindin D‐28K (Calb) neurons with a male‐biased sex difference in cell number (Calb‐SDN ...
Yusa Arai, Shinji Tsukahara
wiley   +1 more source

Erratum to: Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F–DOPA

open access: yesEuropean Journal of Nuclear Medicine and Molecular Imaging, 2017
M. Bozkurt   +14 more
semanticscholar   +1 more source

Somatostatin and cancer

open access: yesMetabolism, 1996
The potential role of somatostatin (SRIF) in the diagnosis and treatment of nonendocrine human cancers is reviewed. There have been many reports of the growth-inhibitory activity of SRIF on normal and transformed cells in vitro. Many processes involved in malignant tumor growth depend on autocrine growth mechanisms, and somatostatin receptors (ssts ...
openaire   +3 more sources

Lower density of calretinin‐immunopositive neurons in the putamen of subjects with schizophrenia

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 505-516, April 2025.
Recent neuroimaging and histological studies highlight the striatum as a key area involved in SCH, but the specific impairment of neuronal subtypes in subcortical structures is not fully understood. This study is the first detailed investigation of neuroanatomical changes in the putamen in SCH, specifically examining the density of calretinin ...
Paz Kelmer   +4 more
wiley   +1 more source

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