Results 51 to 60 of about 136,487 (285)

Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish

Frontiers in Endocrinology, 2022
Feeding and growth are two closely related and important physiological processes in living organisms. Studies in mammals have provided us with a series of characterizations of neuropeptides and their receptors as well as their roles in appetite control ...
Xiaozheng Yu, Haijun Yan, Wensheng Li
doaj   +1 more source

19F NMR spectroscopy monitors ligand binding to recombinantly fluorine-labelled b'x from human protein disulphide isomerase (hPDI) [PDF]

, 2014
We report a protein-observe (19)F NMR-based ligand titration binding study of human PDI b'x with ?-somatostatin that also emphasises the need to optimise recombinant protein fluorination when using 5- or 6-fluoroindole.
Byrne, Crowley, Darby, Denisa Doko, Denisov, Fielding, Freedman, Hatahet, Hatahet, Kirsty L. Richards, Klappa, Koivunen, Mark J. Howard, Michelle L. Rowe, Nakasako, Nguyen, Pirneskoski, Richard A. Williamson, Rose Curtis-Marof, Serve, Tian, Wallis, Wang, Wang, Williamson   +24 more
core   +1 more source

Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High‐Volume Center

Annals of Gastroenterological Surgery, EarlyView.
In patients with NELM, those with < 8 liver metastases and G1/2 tumors are the favorable candidates for liver resection. The important point of this study is that the patients who do not meet the above criteria should be considered for multidisciplinary treatment because of their extremely shorter recurrence‐free period.
Daisuke Asano, Toshitaka Sugawara, Keiichi Akahoshi, Shotaro Gan, Shohei Motohashi, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Atsushi Kudo, Daisuke Ban   +9 more
wiley   +1 more source

Acromegaly in the elderly patient

Archives of Endocrinology and Metabolism, 2020
Acromegaly is an insidious disease, usually resulting from growth hormone hypersecretion by a pituitary adenoma. It is most often diagnosed during the 3rd to 4th decade of life.
Raquel S. Jallad, Marcello D. Bronstein
doaj   +1 more source

Hippocampal Somatostatin Interneurons, Long-Term Synaptic Plasticity and Memory

Frontiers in Neural Circuits, 2021
A distinctive feature of the hippocampal structure is the diversity of inhibitory interneurons. These complex inhibitory interconnections largely contribute to the tight modulation of hippocampal circuitry, as well as to the formation and coordination of
Eve Honoré, Abdessattar Khlaifia, Anthony Bosson, Jean-Claude Lacaille   +3 more
doaj   +1 more source

Towards a Radio-guided Surgery with $\beta^{-}$ Decays: Uptake of a somatostatin analogue (DOTATOC) in Meningioma and High Grade Glioma

, 2014
A novel radio guided surgery (RGS) technique for cerebral tumors using $\beta^{-}$ radiation is being developed. Checking the availability of a radio-tracer that can deliver a $\beta^{-}$ emitter to the tumor is a fundamental step in the deployment of ...
BELLINI, Fabio, Bocci, Valerio, Chiodi, Giacomo, COLLAMATI, FRANCESCO, Cremonesi, Marta, DE LUCIA, Erika, FACCINI, Riccardo, Ferrari, Mahila E., Frallicciardi, Paola M., Grana, Chiara M., Marafini, Michela, Mattei, Ilaria, Morganti, Silvio, PATERA, Vincenzo, PEPE, ALESSANDRA, PIERSANTI, LUCA, PINCI, davide, Recchia, Luigi, RUSSOMANDO, ANDREA, SARTI, ALESSIO, SCIUBBA, Adalberto, SENZACQUA, MARTINA, SOLFAROLI CAMILLOCCI, ELENA, VOENA, Cecilia   +23 more
core   +1 more source

Identifying functional populations among the interneurons in laminae I-III of the spinal dorsal horn [PDF]

, 2017
The spinal dorsal horn receives input from primary afferent axons, which terminate in a modality-specific fashion in different laminae. The incoming somatosensory information is processed through complex synaptic circuits involving excitatory and ...
Todd, Andrew J.
core   +1 more source

Preoperative Aortic Calcification Volume Predicts Postoperative Complications in Nonpancreatic Cancer Patients Undergoing Pancreaticoduodenectomy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background/Objectives Postoperative complications following pancreaticoduodenectomy (PD) remain high, particularly in patients with soft pancreatic texture. Abdominal aortic calcification volume (AACV), a surrogate marker of systemic arteriosclerosis, has been associated with increased surgical risk in lower gastrointestinal procedures ...
Masaki Horiuchi, Kentaro Miyake, Kota Sahara, Jun Yamamoto, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Ryusei Matsuyama, Itaru Endo   +9 more
wiley   +1 more source

Pharmacologic inhibition of somatostatin receptor 2 to restore glucagon counterregulation in diabetes

Frontiers in Pharmacology
Glucose homeostasis is primarily maintained by pancreatic hormones, insulin and glucagon, with an emerging role for a third islet hormone, somatostatin, in regulating insulin and glucagon responses.
Emily G. Hoffman, Ninoschka C. D’Souza, Richard T. Liggins, Michael C. Riddell   +3 more
doaj   +1 more source

DMAP-assisted sulfonylation as an efficient step for the methylation of primary amine motifs on solid support

Beilstein Journal of Organic Chemistry, 2017
Several multistep strategies were developed to ensure single methylation of amines on solid support. These strategies rely on the introduction of the o-NBS protecting/activating group as a key step.
Johnny N. Naoum, Koushik Chandra, Dorit Shemesh, R. Benny Gerber, Chaim Gilon, Mattan Hurevich   +5 more
doaj   +1 more source