Results 71 to 80 of about 128,394 (306)

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Effects of Ostertagia circumcincta larvae and adult parasites on abomasal and intestinal tissues in sheep : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Physiology [PDF]

open access: yes, 1994
Ostertagia circumcincta parasites infect the abomasum of sheep causing damage to the abomasal tissues and significant production losses to the sheep farming industry.
Hodgkinson, Suzanne Marie
core  

Expression of gastrin-releasing peptide by excitatory interneurons in the mouse superficial dorsal horn [PDF]

open access: yes, 2014
Background: Gastrin-releasing peptide (GRP) and its receptor have been shown to play an important role in the sensation of itch. However, although GRP immunoreactivity has been detected in the spinal dorsal horn, there is debate about whether this ...
Gutierrez-Mecinas, Maria   +2 more
core   +1 more source

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

open access: yesGlia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

Molecular theranostics: principles, challenges and controversies

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Cell Type-Specific Expression of Corticotropin-Releasing Hormone-Binding Protein in GABAergic Interneurons in the Prefrontal Cortex

open access: yesFrontiers in Neuroanatomy, 2017
Corticotropin-releasing hormone-binding protein (CRH-BP) is a secreted glycoprotein that binds CRH with very high affinity to modulate CRH receptor activity.
Kyle D. Ketchesin   +5 more
doaj   +1 more source

A Reassessment of the Clinical Utility of 68Ga‐DOTATATE PET/CT in Patients With Gastroenteropancreatic Neuroendocrine Tumors

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background Gastroenteropancreatic neuroendocrine tumors (GEP‐NETs) are a rare and biologically diverse group of tumors that are challenging to image. 68Ga‐DOTATATE PET/CT is the most sensitive imaging tool for these tumors, and while its use has increased over time, its clinical impact remains unclear, particularly for clinical scenarios ...
Orjola Prela   +8 more
wiley   +1 more source

Substance P-expressing excitatory interneurons in the mouse superficial dorsal horn provide a propriospinal input to the lateral spinal nucleus [PDF]

open access: yes, 2018
The superficial dorsal horn (laminae I and II) of the spinal cord contains numerous excitatory and inhibitory interneurons, and recent studies have shown that each of these groups can be divided into several neurochemically distinct populations. Although
Bell, Andrew M.   +4 more
core   +1 more source

Utilizing Peptide Ligand GPCRs to Image and Treat Pancreatic Cancer

open access: yesBiomedicines, 2018
It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75).
Gail L. Matters, John F. Harms
doaj   +1 more source

Breathing and balance: Clinical insights and management strategies of respiratory acid‐base disorders

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Respiratory acidosis and alkalosis are two of the four main acid‐base processes encountered in clinical practice. These two processes are tightly balanced by breathing. Identification and management of respiratory acid‐base disorders are important for clinicians, particularly when caring for patients with underlying pulmonary and neurological ...
Anne M. Tucker, Tami N. Johnson
wiley   +1 more source

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