Results 71 to 80 of about 115,117 (314)
Somatostatin, neuronal vulnerability and behavioral emotionality
Molecular Psychiatry, 2014 Somatostatin (SST) deficits are common pathological features in depression and other neurological disorders with mood disturbances, but little is known about the contribution of SST deficits to mood symptoms or causes of these deficits. Here we show that
Li-Chun Lin, E. Sibille
semanticscholar +1 more source
Utilizing Peptide Ligand GPCRs to Image and Treat Pancreatic Cancer
Biomedicines, 2018 It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75).
Gail L. Matters, John F. Harms
doaj +1 more source
Future Oncology, 2014 Neuroendocrine tumors have shown rising incidence mainly due to higher clinical awareness and better diagnostic tools over the last 30 years. Functional imaging of neuroendocrine tumors with PET tracers is an evolving field that is continuously refining ...
C. B. Johnbeck, U. Knigge, A. Kjær
semanticscholar +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
Glia, EarlyView.Multiple sclerosis involves chronic CNS inflammation and neurodegeneration. This review highlights glial cells as key drivers in progressive MS, focusing on lesion pathology, molecular dysfunction, and human‐relevant model systems. ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive ...
Volker Siffrin
wiley +1 more source
Cell Reports, 2017 Although Netos are considered auxiliary subunits critical for kainate receptor (KAR) function, direct evidence for their regulation of native KARs is limited.
Megan S. Wyeth +13 more
doaj +1 more source
Predictive Factors of Malignancy in Cervical Paragangliomas: A Retrospective Study
Head &Neck, EarlyView.ABSTRACT Background Early predictive factors of metastatic cervical paragangliomas (cPG) are lacking. Methods This multicenter retrospective study included patients with at least one cPG. Metastatic cPG were defined by the histological presence of lymph node metastases or distant metastases.
Garance Haw +13 more
wiley +1 more source
Heterotopic Transplantations Reveal Environmental Influences on Interneuron Diversity and Maturation
Cell Reports, 2017 During embryogenesis, neural progenitors in the ganglionic eminences give rise to diverse GABAergic interneuron subtypes that populate all forebrain regions.
Giulia Quattrocolo +2 more
doaj +1 more source
International Journal of Cancer, EarlyView.Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li +7 more
wiley +1 more source
Indian Journal of Radiology and Imaging, 2017 The somatostatin (SS) receptor scintigraphy (SRS), using octreotide radiolabelled with 111In (Ocreoscan©, OCT), is a consolidated diagnostic procedure in patients with neuroendocrine tumors (NET) because of an increased expression of somatostatin ...
Vincenzo Cuccurullo +3 more
doaj +1 more source