Results 131 to 140 of about 117,026 (248)

Long-term use of somatostatin analogs for chronic gastrointestinal bleeding in hereditary hemorrhagic telangiectasia. [PDF]

Front Med (Lausanne), 2023
Torres-Iglesias R, Mora-Luján JM, Iriarte A, Cerdà P, Alba E, Sánchez-Corral MÁ, Berrozpe A, Cruellas F, Gamundí E, Ribas J, Castellote J, Riera-Mestre A.   +11 more
europepmc   +1 more source

Sex‐Dependent Alterations in Behavioral Development of Mice Lacking α5‐Nicotinic Acetylcholine Receptors

Journal of Neuroscience Research, Volume 104, Issue 10, October 2026.
Loss of α5‐nAChRs drives age‐dependent, sex‐specific behavioral alterations, with females showing early cognitive deficits and males a progressive decline. These findings identify α5‐nAChRs as key regulators of neural circuit maturation and underscore the critical importance of incorporating sex as a biological variable in preclinical research ...
Danai Papavranoussi Daponte, Filippos Marinos, Eleni Matala, Irini Skaliora   +3 more
wiley   +1 more source

The Role of Somatostatin in the Gastrointestinal Tract

Biology
The gastrointestinal (GI) tract is responsible for food digestion and host protection from harmful stimuli; however, its function as an endocrine organ is also well documented. Somatostatin (SST) was first discovered in the hypothalamus, but the GI tract
Konstantinos Papantoniou, Ioanna Aggeletopoulou, Ploutarchos Pastras, Christos Triantos   +3 more
doaj   +1 more source

Neuropathic Pain: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Neuropathic pain arises from peripheral nerve injury, central sensitization, neurotransmitter imbalance, neuroimmune activation, and maladaptive circuit remodeling. Clinical phenotyping and multimodal imaging can identify dominant peripheral and central mechanisms.
Yaling Dai, Mengquan Tan, Man Yuan, Huixian Zhou, Qin Xie, Jiling Zeng, Yixin Yang, Xinran He, Siyuan Song   +8 more
wiley   +1 more source

Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors

, 1995
In 10 patients with histologically proven neuroendocrine tumors (4 carcinoids, 4 pheochromocytomas, 1 medullary thyroid cancer and 1 Merkel tumor) the results of radiolabeled metaiodobenzylguanidine (MIBG) and somatostatin analogs were compared.
Salvatore M., Lastoria S, Varrella P, Maurea S, Klain M, Vergara E, MAUREA, SIMONE, KLAIN, MICHELE, Bernardy JD, SALVATORE, MARCO, ACAMPA, WANDA, Muto P   +11 more
core  

Comparing Somatostatin Analogs in the Treatment of Advanced Gastroenteropancreatic Neuroendocrine Tumors. [PDF]

Oncology, 2022
Allaw MB, Switchenko JM, Khalil L, Wu C, Alese OB, Akce M, Draper A, Jones AT, El-Rayes B, Shaib W.   +9 more
europepmc   +1 more source

Cross‐Talk Between Histamine H2 Receptor and Glucocorticoid Receptor: Potential Implications in Acute Myeloid Leukemia Treatment

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT This study investigates the impact of histamine H2 receptor activation on glucocorticoid receptor (GR)‐mediated transcriptional activity, as well as its effects on leukemic cell proliferation and chemotherapy resistance. We demonstrate that activation of the histamine H2 receptor by its specific agonist, amthamine, enhances GR transcriptional ...
Valeria Torralba‐Agu, Natalia Fernández, Carina Shayo, Carlos Davio, C. Daniel Zappia, Federico Monczor   +5 more
wiley   +1 more source

Budget impact of somatostatin analogs as treatment for metastatic gastroenteropancreatic neuroendocrine tumors in US hospitals

, 2017
Jesse D Ortendahl,1 Sonia J Pulgar,2 Beloo Mirakhur,3 David Cox,3 Tanya GK Bentley,1 Alexandria T Phan4 1Health Economics, Partnership for Health, LLC, Beverly Hills, CA, USA; 2Health Economics and Outcomes Research, Ipsen Biopharmaceuticals, Basking ...
Cox D, Mirakhur B, Bentley TGK, Ortendahl JD, Pulgar SJ, Phan AT   +5 more
core  

Evaluating home injection compared with healthcare-setting injection of somatostatin analogs: a systematic literature review. [PDF]

Endocrine, 2023
Boguszewski CL, Korbonits M, Artignan A, García AM, Houchard A, Ribeiro-Oliveira A, de Herder WW.   +6 more
europepmc   +1 more source

(+)‐Trans‐Cannabidiol Is an Agonist at Human CB2 Receptors

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT (−)‐trans‐Cannabidiol ((−)‐CBD) is a principal phytocannabinoid from Cannabis sativa. (−)‐CBD has complex pharmacology but is a relatively weak inhibitor of CB1 and CB2 receptor signaling. Cannabidiol has two chiral centres and thus four stereoisomers.
Pedro Bans Burtchaell, Marina Junqueira Santiago, Chenxi Wang, Mehdi Hagdoost, Evie J. M. Clay, Dani Mohnot, Mark Connor   +6 more
wiley   +1 more source