Results 141 to 150 of about 675,123 (288)

Diffuse and Prolonged Bone Pain Revealing Tumor‐Induced Osteomalacia: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Tumor‐induced osteomalacia should be considered in patients with unexplained bone pain and fractures. Advanced imaging, such as Ga68‐DOTATATE PET/CT, enables precise tumor localization, and surgical excision can rapidly normalize phosphate metabolism and resolve symptoms, underscoring the importance of early diagnosis and intervention.
Rahman Amraei   +3 more
wiley   +1 more source

Case Report of IgG4‐Related Autoimmune Pancreatitis

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT This case presents a clear diagnosis with a complete chain of clinical evidence. Long‐term follow‐up revealed that, despite excellent disease control, the condition relapsed more than 6 months after discontinuation of glucocorticoids, with a tendency toward further progression.
Rui Yu   +7 more
wiley   +1 more source

A Case of Heart Failure With Reduced Ejection Fraction Secondary to Dilated Cardiomyopathy due to Long‐Standing Untreated Acromegaly: A Case Report and Focused Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic findings in dilated cardiomyopathy secondary to untreated acromegaly. (A) Apical four‐chamber view showing biventricular and biatrial dilation. (B‐C) Colour Doppler demonstrating mitral, aortic, and tricuspid regurgitation. (D) Reduced global longitudinal strain (GLS: −6.5%), consistent with severe systolic dysfunction.
Cristian Orlando Porras Bueno   +4 more
wiley   +1 more source

Management Strategies for Refractory Esophageal Varices

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley   +1 more source

Resistance to Somatostatin Analogs in Italian Acromegaly Patients: The MISS Study. [PDF]

open access: yesJ Clin Med, 2022
Berton AM   +12 more
europepmc   +1 more source

Bidirectional Roles of TRPV1 in a Latent Sensitization Model of Myofascial Low Back Pain

open access: yesEuropean Journal of Pain, Volume 30, Issue 4, April 2026.
ABSTRACT Introduction Chronic primary low back pain (cpLBP) is a global health concern with poorly understood pathomechanisms, potentially involving spinal sensitization. The capsaicin receptor TRPV1 plays a crucial role in sensitization across pain models.
Vivian Blechschmidt   +6 more
wiley   +1 more source

Long-term use of somatostatin analogs for chronic gastrointestinal bleeding in hereditary hemorrhagic telangiectasia. [PDF]

open access: yesFront Med (Lausanne), 2023
Torres-Iglesias R   +11 more
europepmc   +1 more source

Neuronal Activity Promotes Node‐Like Cluster Assembly Prior to Myelination and Remyelination in the Central Nervous System

open access: yesGlia, Volume 74, Issue 4, April 2026.
Ronzano et al. show that neuronal activity promotes node‐like cluster (NLC) formation before (re)myelination by regulating β1Nav and Nav1.1, which are essential for NLC assembly. This may represent an intermediate step in activity‐driven myelination and contribute to the regulation of axonal conduction.
Rémi Ronzano   +10 more
wiley   +1 more source

The Role of Somatostatin in the Gastrointestinal Tract

open access: yesBiology
The gastrointestinal (GI) tract is responsible for food digestion and host protection from harmful stimuli; however, its function as an endocrine organ is also well documented. Somatostatin (SST) was first discovered in the hypothalamus, but the GI tract
Konstantinos Papantoniou   +3 more
doaj   +1 more source

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