Results 171 to 180 of about 8,855 (217)

The Role of Somatostatin Analogs in Cushing's Disease

Pituitary, 2004
Somatostatin (SRIF) has been proposed to be of therapeutic interest in the medical treatment of Cushing's disease. While in vitro data demonstrate the presence of SRIF-receptor subtype (sst) expression in corticotroph adenomas, the current clinically available SRIF-analog Octreotide, predominantly targeting sst(2), is ineffective in lowering ACTH ...
van der Hoek, Joost, Lamberts, S.W.J., Hofland, Leo   +2 more
openaire   +3 more sources

Octreotide: A Synthetic Analog of Somatostatin

Drug Intelligence & Clinical Pharmacy, 1988
Octreotide is an investigational synthetic peptide exhibiting actions similar to those of endogenous somatostatin. It has a longer half-life than the native hormone and can be administered by subcutaneous injection. Octreotide inhibits the secretion of growth hormone and numerous regulatory peptides of the gastroenteropancreatic system.
openaire   +2 more sources

[Somatostatin analogs in oncology].

Bulletin du cancer, 1991
Somatostatin octapeptide analogues have a longer half-life and are more potent than natural somatostatin (SS-14). Somatostatin analogues are presently approved for the treatment of gastrointestinal (GI) endocrine cancers such as carcinoids, vipomas and glucagonomas.
F, Thomas, H, Parmar, G, Prevost, J M, Kuhn, J L, Bejot, J P, Moreau, A, Bogden   +6 more
openaire   +1 more source

Somatostatin Receptor Splicing Variant sst5TMD4 Overexpression in Glioblastoma Is Associated with Poor Survival, Increased Aggressiveness Features, and Somatostatin Analogs Resistance

International Journal of Molecular Sciences, 2022
Justo P Castaño, Manuel D Gahete, Raúl M Luque   +2 more
exaly  

Somatostatin: The Search for Analogs

Science, 1975
openaire   +2 more sources

[Somatostatin, somatostatin analogs and their clinical use].

Casopis lekaru ceskych, 2003
Somatostatin is a hormone with broad spectrum of physiological effects. Somatostatin and its analogues are employed in the diagnosis and treatment of various clinical conditions. The article reviews the use of somatostatine and somatostatine analogues in the clinical medicine.
openaire   +1 more source

Consensus report on the use of somatostatin analogs for the management of neuroendocrine tumors of the gastroenteropancreatic system

Annals of Oncology, 2004
Bertram Wiedenmann, Wouter De Herder, Guido Rindi   +2 more
exaly  

Somatostatin analogs: does pharmacology impact antitumor efficacy?

Trends in Endocrinology and Metabolism, 2014
Philippe Caron, Corinne Bousquet, Stéphane Pyronnet   +2 more
exaly  

Somatostatin Analogs as Radiodiagnostic Tools

Reviews in Endocrine and Metabolic Disorders, 2005
Wouter W, de Herder, Steven W J, Lamberts   +1 more
openaire   +2 more sources

Somatostatin analogs

1979
HIRSCHMANN RALPH F, HOLLY FREDERICK W, NUTT RUTH F, PALEVEDA WILLIAM J, STRACHAN ROBERT G, VEBER DANIEL F   +5 more
openaire   +5 more sources