Results 231 to 240 of about 677,503 (281)

Two Types of Somatostatin Receptors Differentiated by Cyclic Somatostatin Analogs

Science, 1985
Somatostatin receptors in rat brain, pituitary, and pancreas were labeled with two radioiodinated analogs of somatostatins 14 and 28. Two cyclic analogs of somatostatin, SMS201-995 and cyclo(Ala-Cys-Phe-D-Trp-Lys-Thr-Cys), showed biphasic displacement of binding to somatostatin receptors by these radioligands.
V T, Tran, M F, Beal, J B, Martin
openaire   +2 more sources

Intrathecal somatostatin, somatostatin analogs, substance P analog and dynorphin A cause comparable neurotoxicity in rats

Neuroscience, 1990
Rats chronically implanted with intrathecal catheters received intrathecal injections (10 microliters followed by 10 microliters saline flush) of either saline (n = 5), somatostatin (100 micrograms, n = 10), the somatostatin analog BIM 23003 (100 micrograms, n = 5), the somatostatin analog SMS 201-995 (100 micrograms, n = 5), the substance P analog [D ...
D M, Gaumann, T S, Grabow, T L, Yaksh, S J, Casey, M, Rodriguez   +4 more
openaire   +2 more sources

[Somatostatin analogs in oncology].

Bulletin du cancer, 1991
Somatostatin octapeptide analogues have a longer half-life and are more potent than natural somatostatin (SS-14). Somatostatin analogues are presently approved for the treatment of gastrointestinal (GI) endocrine cancers such as carcinoids, vipomas and glucagonomas.
F, Thomas, H, Parmar, G, Prevost, J M, Kuhn, J L, Bejot, J P, Moreau, A, Bogden   +6 more
openaire   +1 more source

Octreotide: A Synthetic Analog of Somatostatin

Drug Intelligence & Clinical Pharmacy, 1988
Octreotide is an investigational synthetic peptide exhibiting actions similar to those of endogenous somatostatin. It has a longer half-life than the native hormone and can be administered by subcutaneous injection. Octreotide inhibits the secretion of growth hormone and numerous regulatory peptides of the gastroenteropancreatic system.
openaire   +2 more sources

Radiolabeled Somatostatin Analogs for Cancer Imaging

Seminars in Nuclear Medicine
Somatostatin receptors (SSTR) are expressed by many tumours especially those related to neuro-endocrine origin and molecular functional imaging of SSTR expression using radiolabelled somatostatin analogs have revolutionized imaging of patients with these group of malignancies.
Aamir K. Nazar, Sandip Basu
openaire   +2 more sources

68Ga-Somatostatine Analogs: Rare Diseases

2012
A 56-year-old male patient was diagnosed with a pancreatic mass at ultrasound and was therefore referred for a 68Ga-DOTA NOC PET/CT to assess the presence of somatostatin receptors (Fig. 74.1). The scan result was negative. The patient was subsequently operated on, and the final diagnosis was cystic serous adenocarcinoma of the pancreas.
Cristina Nanni, Stefano Fanti
openaire   +1 more source

[Somatostatin, somatostatin analogs and their clinical use].

Casopis lekaru ceskych, 2003
Somatostatin is a hormone with broad spectrum of physiological effects. Somatostatin and its analogues are employed in the diagnosis and treatment of various clinical conditions. The article reviews the use of somatostatine and somatostatine analogues in the clinical medicine.
openaire   +1 more source

High interlaboratory and interobserver agreement of somatostatin receptor immunohistochemical determination and correlation with response to somatostatin analogs.

Human Pathology, 2018
A. Kasajima, M. Papotti, W. Ito, M. Brizzi, A. La Salvia, I. Rapa, Tomoyoshi Tachibana, S. Yazdani, H. Sasano, M. Volante   +9 more
semanticscholar   +1 more source

Quantitative analyses of T2-weighted MRI as a potential marker for response to somatostatin analogs in newly diagnosed acromegaly

Endocrine, 2016
A. Heck, K. Emblem, O. Casar-Borota, J. Bollerslev, G. Ringstad   +4 more
semanticscholar   +1 more source

Somatostatin Analogs as Radiodiagnostic Tools

Reviews in Endocrine and Metabolic Disorders, 2005
Wouter W, de Herder, Steven W J, Lamberts   +1 more
openaire   +2 more sources