Results 121 to 130 of about 2,397,304 (343)

Effects of cell therapy on seizures in animal models of epilepsy: Systematic review and meta‐analysis

Epilepsia, EarlyView.
Abstract This study was undertaken to systematically evaluate the efficacy of cell therapy in reducing seizures in animal models of chronic epilepsy. Three databases, Ovid MEDLINE, Ovid Embase, and Web of Science, were searched using predetermined eligibility criteria.
Afaf S. Altalhi, Muhammad S. Javaid, Nigel C. Jones, Kim L. Powell, Patrick Kwan, Terence J. O'Brien, Ana Antonic‐Baker   +6 more
wiley   +1 more source

Nanoparticle‐encapsulated neuropeptide Y provides robust seizure protection in SCN1A‐derived epilepsy

Epilepsia, EarlyView.
Abstract Objective Neuropeptides have garnered great interest as potential treatments for epilepsy due to their impact on neuronal excitability through modulation of ion channels and neurotransmitter receptor activity. Neuropeptide Y (NPY) is a 36‐amino acid neuropeptide that is expressed primarily by γ‐aminobutyric acidergic (GABAergic) interneurons ...
Samantha L. Reed, Lauren M. Aiani, Eesha Faiz, Emmanuel Adediran, Morris Benveniste, Kevin S. Murnane, Martin D'Souza, Andrew Escayg, Jennifer C. Wong   +8 more
wiley   +1 more source

The histamine H₃ receptor agonistN^α-methylhistamine produced byHelicobacter pylori does not alter somatostatin release from cultured rabbit fundic D-cells [PDF]

, 1998
I L P Beales, J Calam
openalex   +1 more source

Signaling Can Be Uncoupled from Imaging of the Somatostatin Receptor Type 2

Molecular Imaging, 2007
Endogenous and exogenous somatostatin receptors are commonly targeted for imaging using radiopharmaceutical analogues of somatostatin. Ligand binding activates receptor-mediated signaling.
Lin Han, Dan Yang, Vikas Kundra
doaj   +1 more source

C1q neutralization during epileptogenesis attenuates complement‐mediated synaptic elimination and epileptiform activity

Epilepsia, EarlyView.
Abstract Objective Accumulating evidence indicates that aberrant C1q‐C3 complement signaling in microglia and astrocytes drives synaptic dysfunction and neuronal loss. C1q‐mediated synaptic dysfunction disrupts neuronal circuitry balance and can lead to network hyperexcitability in epilepsy.
Yoonyi Jeong, Hyun‐Kyoung Lim, Hayeon Kim, Juheon Lee, Siyoon Lee, Minah Suh   +5 more
wiley   +1 more source

Somatostatin and opioid receptors do not regulate proliferation or apoptosis of the human multiple myeloma U266 cells [PDF]

, 2009
Céline Kerros, Thibault Cavey, Brigitte Sola, Philippe Jauzac, Stéphane Allouche   +4 more
openalex   +1 more source

Supplementary table 1 from ¹⁷⁷Lu-DOTA-EB-TATE, a Radiolabeled Analogue of Somatostatin Receptor Type 2, for the Imaging and Treatment of Thyroid Cancer

, 2023
Shilpa Thakur, Brianna Daley, Corina Millo, Craig Cochran, Orit Jacobson, Huiyan Lu, Zhantong Wang, Dale O. Kiesewetter, Xiaohong Chen, Vasyl Vasko, Joanna Kłubo-Gwieździńska   +10 more
openalex   +1 more source

Somatostatinergic systems: an update on brain functions in normal and pathological aging

Frontiers in Endocrinology, 2012
Somatostatin is highly expressed in mammalian brain and is involved in many brain functions such as motor activity, sleep, sensory and cognitive processes. Five somatostatin receptors have been described: sst1, sst2 (A and B), sst3 to 5, all belonging to
Guillaume eMartel, Guillaume eMartel, Patrick eDutar, Patrick eDutar, Jacques eEpelbaum, Jacques eEpelbaum, Cécile eViollet, Cécile eViollet   +7 more
doaj   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang, Theng Yi Tay, Simon Gibbs, Ola Niewiadomski   +3 more
wiley   +1 more source

Ectopic Expression of α6 and δ GABA_AReceptor Subunits in Hilar Somatostatin Neurons Increases Tonic Inhibition and Alters Network Activity in the Dentate Gyrus [PDF]

, 2015
Xiaoping Tong, Zechun Peng, Nianhui Zhang, Yliana Cetina, Christine Huang, Martin Wallner, Thomas S. Otis, Carolyn R. Houser   +7 more
openalex   +1 more source