Results 131 to 140 of about 2,397,304 (343)

Controversies in NEN: An ENETS position statement on the endoscopic management of localised gastric, duodenal and rectal neuroendocrine neoplasms

Journal of Neuroendocrinology, EarlyView.
Abstract Gastric, duodenal and rectal neuroendocrine tumours (NETs) are increasingly detected due to advances in endoscopic imaging. While international guidelines provide criteria for endoscopic management, several aspects remain controversial due to limited high‐quality evidence.
Francesco Panzuto, Dermot O'Toole, Günter Klöppel, Ulrich Peter Knigge, Günter Josef Krejs, Marina Tsoli, Marco Volante, Tu Vinh Luong   +7 more
wiley   +1 more source

Controversies in NEN: An ENETS position statement on nutritional support in neuroendocrine neoplasms

Journal of Neuroendocrinology, EarlyView.
Abstract Neuroendocrine neoplasms (NEN) themselves and also their treatment may cause malnutrition, inducing changes in physiological behaviour and eventually leading to increased rates of morbidity and mortality. Malnutrition is a common, under‐recognised and under‐treated condition in patients with NEN, and there are limited data available on the ...
Simona Grozinsky‐Glasberg, Johannes Hofland, Stephanie Alband, Yasmin Chotai de Lima, Adina Croitoru, Wanda Geilvoet, Peter Igaz, Beata Kos‐Kudła, Guenter J. Krejs, Alessandro Laviano, Francesco Panzuto, Anguraj Sadanandam, Ana Paula Santos, Staffan Welin, Rajaventhan Srirajaskanthan, V. Ambrosini, D. K. Bartsch, E. Baudin, N. Begum, E. Christ, J. Cros, T. Denecke, C. M. Deroose, C. Dromain, M. Falconi, N. Fazio, L. Fernandez‐Cuesta, R. Garcia‐Carbonero, A. Grossman, G. Kaltsas, A. Kasajima, A. Kjaer, G. Klöppel, U. P. Knigge, A. Lamarca, S. W. Langer, T. V. Luong, W. Martin, M. McNamara, D. O'Toole, S. Partelli, M. Pavel, A. Perren, R. Salazar, J. Schrader, H. Sorbye, A. Sowa‐Staszczak, E.‐J. Speel, P. Stalberg, M. Tesselaar, E. Tiensuu Janson, M. Tsoli, M. Volante, T. Walter   +53 more
wiley   +1 more source

Controversies in NEN: An ENETS position statement on the treatment of patients with Grade 3 well‐differentiated neuroendocrine tumours of the gastro‐enteropancreatic tract

Journal of Neuroendocrinology, EarlyView.
Abstract Grade 3 neuroendocrine tumours (NET G3) represent approximately 20% of high‐grade neuroendocrine neoplasms, and the recent identification of this entity has given rise to many unanswered questions relating to clinical management. The prognosis for these patients is worse than for those with Grade 1–2 well‐differentiated NET, but better than ...
Mairéad G. McNamara, Halfdan Sorbye, Nehara Begum, Emanuel Christ, Nicola Fazio, Lynnette Fernandez‐Cuesta, Rocio Garcia‐Carbonero, Gregory Kaltsas, Atsuko Kasajima, Ramon Salazar, Ernst Jan M. Speel, Andreas Kjaer   +11 more
wiley   +1 more source

Characterization of Somatostatin Receptor Subtype 2 Expression in Stably Transfected A-427 Human Cancer Cells

Molecular Imaging, 2007
Although radiolabeled somatostatin analogs have become highly prevalent in the diagnosis and treatment of somatostatin receptor subtype (sst)-positive tumors, there are relatively few options with respect to sst-positive tumor cell lines and animal ...
Jesse J. Parry, Martin Eiblmaier, Rebecca Andrews, Laura A. Meyer, Ryuji Higashikubo, Carolyn J. Anderson, Buck E. Rogers   +6 more
doaj   +1 more source

Systematic review and meta‐analysis of the efficacy and safety of [177Lu]Lu‐edotreotide ([177Lu]Lu‐DOTATOC) for the treatment of neuroendocrine tumors

Journal of Neuroendocrinology, EarlyView.
Abstract [177Lu]Lu‐edotreotide is a radiopharmaceutical therapy (RPT) targeting somatostatin receptors, which are commonly overexpressed on neuroendocrine tumors (NETs). This systematic literature review and meta‐analysis describes the efficacy and safety of [177Lu]Lu‐edotreotide in patients with NETs.
Richard P. Baum, Julia G. Fricke, Tristan Ruhwedel, Holger Amthauer, Erika Patricia Azorin‐Vega, Dieter Hörsch, Riccardo Laudicella, Vikalp Maheshwari, Martin A. Walter, Berna Degirmenci Polack, Simon F. Spiegl, Guillaume P. Nicolas   +11 more
wiley   +1 more source

Somatostatin analogs in neuroendocrine tumors with Ki‐67 index of ≥10%

Journal of Neuroendocrinology, EarlyView.
Abstract Somatostatin analogs (SSAs) are an established first‐line therapy in intestinal and pancreatic neuroendocrine tumors (NETs). Based on Phase III studies, their use is recommended in NET with a Ki‐67 index of up to 10%. The effect of first‐line SSA therapy on differentiated NET with a Ki‐67 index ≥10% is poorly understood.
Johanna Braegelmann, Annie Mathew, Boerge Schmidt, Hamza Kalisch, Wolfgang P. Fendler, Dagmar Führer‐Sakel, Harald Lahner   +6 more
wiley   +1 more source

Immunohistochemical assessment and clinical, histopathologic, and molecular correlates of membranous somatostatin type-2A receptor expression in high-risk pediatric central nervous system tumors [PDF]

, 2022
Margot Lazow, Christine Fuller, Andrew T. Trout, Joseph Stanek, Jaime Reuss, Brian Turpin, Sara Szabo, Ralph Salloum   +7 more
openalex   +1 more source

Bone metastases from neuroendocrine neoplasms: Results of an Italian nationwide survey of natural history and management

Journal of Neuroendocrinology, EarlyView.
Abstract Bone metastases (BMs) were reported in <15% of cases of neuroendocrine neoplasms (NENs). Their clinical behavior is various and clinical management is still undefined. This study aimed to describe the clinical practical management and survival outcome of neuroendocrine neoplasm patients with BMs.
Nicola Fazio, Patrick Maisonneuve, Anna Maria Frezza, Nicoletta Ranallo, Toni Ibrahim, Anna La Salvia, Maria Pia Brizzi, Chiara De Divitiis, Salvatore Tafuto, Sara Pusceddu, Riccardo Marconcini, Mauro Cives, Cristina Ferrari, Davide Campana, Delia De Lisi, Daniele Santini, Antongiulio Faggiano, Roberta Modica, Sara Massironi, Antonio Bianchi, Francesco Panzuto, Lorenzo Antonuzzo, Elisa Pellegrini, Vito Amoroso, Ivana Puliafito, Elettra Merola, Nicola Silvestris, Chiara Maria Grana, Francesca Spada   +28 more
wiley   +1 more source

The gatekeepers of growth: The neural roles and regulation of growth hormone‐releasing hormone neurons

Journal of Neuroendocrinology, EarlyView.
Abstract The neuroendocrine control of growth is mediated by the hypothalamic–pituitary–somatic (HPS) axis. This involves the hypothalamic release of growth hormone‐releasing hormone (GHRH), which stimulates the pituitary secretion of growth hormone (GH).
Bradley B. Jamieson
wiley   +1 more source

11C‐Hydroxyephedrine PET/CT for preoperative surgical planning in large pheochromocytoma and paraganglioma

Journal of Neuroendocrinology, EarlyView.
Abstract Early detection of metastases and timely surgical intervention play a crucial role in the management of neuroendocrine tumors. In large‐sized pheochromocytomas and sympathetic paragangliomas (PPGL), functional imaging with positron emission tomography (PET) is recommended, as it improves the detection of metastases, which may go undetected on ...
Achyut Ram Vyakaranam, Olov Norlén, Alina Akural, Joakim Crona, Matilda Annebäck, Branislav Klimàcek, Peter Stålberg, Anders Sundin, Tobias Åkerström   +8 more
wiley   +1 more source