Results 171 to 180 of about 2,397,304 (343)

Intranasal Insulin Mitigates Memory Impairment and Neuroinflammation in a Mouse Model of Hippocampal Aging

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 6, December 2025.
ABSTRACT Aging is a complex process that frequently includes cognitive decline with memory loss. In the hippocampus, the number of somatostatin‐positive (Sst+) GABAergic interneurons in the hilar region of the dentate gyrus decreases with age. We previously showed that selective ablation of Sst+ dentate hilar interneurons is sufficient to induce ...
Rajasekar Nagarajan   +5 more
wiley   +1 more source

Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality

open access: yesNeuropsychopharmacology, 2017
T. Prévot   +7 more
semanticscholar   +1 more source

Boosting the engraftment of subcutaneously transplanted pancreatic islets by nanofat

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7258-7274, December 2025.
Abstract Aims In the therapy of type 1 diabetes mellitus, the subcutaneous space has been suggested to be a clinically preferable transplantation site for pancreatic islets due to its easy accessibility. However, its poor vascularisation capacity and, thus, challenging environment typically result in islet engraftment failure.
Selina Wrublewsky   +11 more
wiley   +1 more source

Somatostatin Receptor Desensitization in NG108-15 Cells [PDF]

open access: hybrid, 1998
Vahri Beaumont   +4 more
openalex   +1 more source

Gene Expression Analysis Provides Insights Into the Functional and Developmental Differentiations of Pleopodal Lungs in a Terrestrial Isopod Crustacean, Porcellio scaber

open access: yesEvolution &Development, Volume 27, Issue 4, December 2025.
Transcriptomic analysis of pleopods in Porcellio scaber reveals gene expression linked to pleopodal lung development, identifying candidate regulatory genes and highlighting developmental changes as drivers of lung development in terrestrial isopod crustaceans.
Naoto Inui   +5 more
wiley   +1 more source

Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer

open access: gold, 2017
Simone U. Dalm   +9 more
openalex   +2 more sources

MRI‐based surrogates of brain clearance in narcolepsy type 1

open access: yesJournal of Sleep Research, Volume 34, Issue 6, December 2025.
Summary Brain clearance involves the drainage of waste molecules from the brain, a process that is suggested to be amplified during sleep. Recently proposed MRI‐based methods attempt to approximate human brain clearance with surrogate measures. The current study aimed to explore whether two brain clearance surrogates are altered in narcolepsy.
Eva M. van Heese   +6 more
wiley   +1 more source

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