Results 181 to 190 of about 39,903 (228)
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Evolutionary history of the somatostatin and somatostatin receptors
Journal of Genetics, 2009Somatostatin and its receptors have a critical role in mammalian growth through their control pattern of secretion of growth hormone, but the evolutionary history of somatostatin and somatostatin receptors are ill defined. We used comparative whole genome analysis of Danio rerio, Carassius auratus, Xenopus tropicalis, Gallus gallus, Monodelphis ...
Muhammad, Moaeen-ud-Din, Li Guo, Yang
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Somatostatin and somatostatin receptors in fish growth
General and Comparative Endocrinology, 2010Multiple forms of somatostatin (SS) and SS receptors (SSTR) are produced widely in the tissues of fish and interact to coordinate numerous physiological processes. Insight into their role in growth regulation emerged from studies of abnormal growth and of whole animals.
Mark A, Sheridan, Alison L, Hagemeister
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Somatostatin, Somatostatin Receptors, and Pancreatic Cancer
World Journal of Surgery, 2005AbstractSomatostatin may play an important role in the regulation of cancer growth including pancreatic cancer by interaction with somatostatin receptors (SSTRs) on the cell surface. Five SSTRs were cloned, and the function of these SSTRs is addressed in this review.
Min, Li +6 more
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European Journal of Nuclear Medicine and Molecular Imaging, 2012
Somatostatin is a peptide with a broad distribution in the nervous system and acts as a neurotransmitter in several organs, having a wide range of mainly inhibiting effects, such as the suppression of growth hormone release, as well as the inhibition of pancreatic and gastrointestinal hormone release.
Giovanna, Pepe +3 more
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Somatostatin is a peptide with a broad distribution in the nervous system and acts as a neurotransmitter in several organs, having a wide range of mainly inhibiting effects, such as the suppression of growth hormone release, as well as the inhibition of pancreatic and gastrointestinal hormone release.
Giovanna, Pepe +3 more
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Scandinavian Journal of Gastroenterology, 1986
More insight into the biochemical structure and operation of the somatostatin receptor(s) has been gained in recent years from several approaches. The minimal active structure of the receptor(s) has been identified, and active minisomatostatins have been synthesized.
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More insight into the biochemical structure and operation of the somatostatin receptor(s) has been gained in recent years from several approaches. The minimal active structure of the receptor(s) has been identified, and active minisomatostatins have been synthesized.
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Seminars in Nuclear Medicine, 2002
[(111)In-DTPA(0)]octreotide is a radiopharmaceutical with a great potential for the visualization of somatostatin receptor-positive tumors. The overall sensitivity of Somatostatin Receptor Imaging (SRI) to localize neuroendocrine tumors is high.
Kwekkeboom, Dik, Krenning, Eric
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[(111)In-DTPA(0)]octreotide is a radiopharmaceutical with a great potential for the visualization of somatostatin receptor-positive tumors. The overall sensitivity of Somatostatin Receptor Imaging (SRI) to localize neuroendocrine tumors is high.
Kwekkeboom, Dik, Krenning, Eric
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Somatostatin receptors in gliomas
Journal of Physiology-Paris, 2000Gliomas differ from non-malignant glial cells in the overexpression or mutations of genes involved in cell cycle or growth regulation. One example is the overexpression of the somatostatin receptor subtype 2 (sst2), especially of the splice variant sst2A. The reasons for this overexpression are not known.
J, Held-Feindt +3 more
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Somatostatins and their receptors in fish
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2001Somatostatin (SRIF) is a multigene family of peptides. SRIF-14 is conserved with identical primary structure in species across the vertebrates. The presence of multiple SRIF genes has been demonstrated in a number of fish species. Notably, three distinct SRIF genes have been identified in goldfish. One of these genes, which encodes [Pro(2)]SRIF-14, has
X, Lin, R E, Peter
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Somatostatin and Somatostatin Receptor Physiology
Endocrine, 2003Since the discovery of somatostatin (SST) over three decades ago, its ubiquitous distribution and manifold functions are still being documented. SST is synthesized in the hypothalamus and transported to the anterior pituitary gland where it tonicaly inhibits GH and TSH secretion as well as being responsible for GH pulsatile release.
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Somatostatin receptors in the adrenal
Molecular and Cellular Endocrinology, 1986Somatostatin receptors have been visualized in the adrenal by autoradiography using the iodinated Tyr3 derivative of the somatostatin octapeptide analog SMS 201-995 (H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr(ol), Sandostatin*). In the rat adrenal gland somatostatin receptors are not exclusively restricted to the glomerulosa cell layer, but can also be ...
R, Maurer, J C, Reubi
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