Results 171 to 180 of about 39,903 (228)

Advances in the Oral Administration of Somatostatin Receptor Ligands in Acromegaly: A Systematic Review Focusing on Biochemical Response. [PDF]

Pharmaceutics
Reverdiau C, Denimal D.
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Somatostatin receptor-targeted polymeric nanoplatform for efficient CRISPR/Cas9 gene editing to enhance synergistic hepatocellular carcinoma therapy. [PDF]

J Nanobiotechnology
Zhang S, Li M, Zeng J, Zhou S, Yue F, Chen Z, Ma L, Wang Y, Wang F, Luo J.   +9 more
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Acromegaly Disease Control Maintained After Switching From Injected Somatostatin Receptor Ligands to Oral Paltusotine.

J Clin Endocrinol Metab
Gadelha MR, Casagrande A, Strasburger CJ, Bidlingmaier M, Snyder PJ, Guitelman MA, Boguszewski CL, Buchfelder M, Shimon I, Raverot G, Tóth M, Mezősi E, Doknic M, Fan X, Clemmons D, Trainer PJ, Struthers RS, Krasner A, Biller BMK.   +18 more
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Somatostatin Receptors

Trends in Endocrinology and Metabolism, 1985
It is now well established that the biological actions of tetradecapeptide somatostatin (somatostatin-14, S-14) are receptor-mediated. These receptors were first quantified in GH4C pituitary tumor cells using [125I-Tyr1] S-14 as radioligand which was found to exhibit high non-specific binding to membrane receptor preparations from normal tissues.
Y C, Patel, C B, Srikant
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Somatostatin receptors

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1995
Somatostatin induces its biological actions by activating a family of receptor subtypes. The recent cloning of five somatostatin receptor subtypes has led to the development of subtype-selective agonists. These compounds are revealing distinct functions of the individual receptor subtypes.
R. A. James, D. R. Weightman
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Somatostatin Receptors

Digestion, 2000
Somatostatin is a neuropeptide produced by neuroendocrine, inflammatory and immune cells in response to different stimuli. Somatostatin inhibits various cellular functions including secretions, motility and proliferation. Its action is mediated by five specific somatostatin receptors (sst1-sst5) which belong to the G protein-coupled receptor family ...
N, Benali, G, Ferjoux, E, Puente, L, Buscail, C, Susini   +4 more
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Somatostatin and Somatostatin Receptors

2009
The biological effects of somatostatin (SST) were first encountered unexpectedly in the late 1960s in two unrelated studies, one by Krulich et al. (1968) who reported on a growth hormone (GH)-releasing inhibitory substance from hypothalamic extracts, and the other, by Hellman and Lernmark (1969), on the presence of a potent insulin inhibitory factor ...
Ujendra, Kumar, Michael, Grant
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Somatostatin Receptors in the Orbits

Clinical Nuclear Medicine, 1995
In-111 pentetreotide has been recommended for the detection of somatostatin receptor (SSR) positive tumors. Sites with increased numbers of activated lymphocytes may also show In-111 pentetreotide with Graves' ophthalmopathy (GO) compared to various other orbital disorders.
DURAK, I, YUREKLI, Y, KAYNAK, S, DURAK, H, ERGIN, M   +4 more
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Somatostatin Receptor Manipulation

Digestion, 2009
The expression of somatostatin receptors (ssts) on human tumours is the basis for the successful therapeutic and diagnostic application of (radiolabelled) somatostatin analogues. Manipulation (up-regulation) of sst expression might improve the uptake of radioligand in in vivo scintigraphy of human sst-positive tumours, as well as the potential success ...
Visser-Wisselaar, H. A., Hofland, L. J., Van Uffelen, C. J.C., Van Koetsveld, P. M., Lamberts, S. W.J.   +4 more
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