Results 21 to 30 of about 30,172 (220)

Activation of Muscarinic Acetylcholine Receptor Subtype 4 is Essential for Cholinergic Stimulation of Gastric Acid Secretion - Relation To D Cell/Somatostatin -

open access: yesFrontiers in Pharmacology, 2016
Background/Aim: Muscarinic acetylcholine receptors exist in five subtypes (M1~M5), and they are widely expressed in various tissues to mediate diverse autonomic functions, including gastric secretion.
Koji Takeuchi   +4 more
doaj   +1 more source

Competitive RT-PCR Strategy for Quantitative Evaluation of the Expression of Tilapia (Oreochromis niloticus) Growth Hormone Receptor Type I

open access: yesBiological Procedures Online, 2009
Quantization of gene expression requires that an accurate measurement of a specific transcript is made. In this paper, a quantitative reverse transcription-polymerase chain reaction (RT-PCR) by competition for tilapia growth hormone receptor type I is ...
Rodríguez-Mallon Alina   +5 more
doaj   +3 more sources

Comparative study of somatostatin-human serum albumin fusion proteins and natural somatostatin on receptor binding, internalization and activation.

open access: yesPLoS ONE, 2014
Albumin fusion technology, the combination of small molecular proteins or peptides with human serum albumin (HSA), is an effective method for improving the medicinal values of natural small molecular proteins or peptides.
Ying Peng   +7 more
doaj   +1 more source

The somatostatinergic system in the mammalian cochlea

open access: yesBMC Neuroscience, 2011
Background Little is known about expression and function of the somatostatinergic system in the mammalian cochlea. We have previously shown that somatostatin administration may have a protective effect on gentamicin-induced hair cell loss. In this study,
Kapfhammer Josef P   +5 more
doaj   +1 more source

A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation. [PDF]

open access: yesPLoS ONE, 2012
The newly developed multireceptor somatostatin analogs pasireotide (SOM230), octreotide and somatoprim (DG3173) have primarily been characterized according to their binding profiles.
Andrea Kliewer   +4 more
doaj   +1 more source

Somatostatin receptors in human adrenal gland tumors--immunohistochemical study.

open access: yesFolia Histochemica et Cytobiologica, 2008
Somatostatin receptors subtypes (SSTR 1-5) were demonstrated in surgically obtained adrenal gland tumors by means of immunohistochemistry (IHC). Results of the present study demonstrate that somatostatin receptors are expressed in adrenal tumors in a ...
Tomasz Stepień   +3 more
doaj   +1 more source

Somatostatin and somatostatin receptors in Cushing's disease [PDF]

open access: yesMolecular and Cellular Endocrinology, 2008
Cushing's disease is caused by an ACTH secreting pituitary adenoma. Surgery is the treatment of choice and cure rates between 60 and 90% are reported. For patients in which surgery fails, effective medical treatment options are needed. Somatostatin (SS) receptors (sst) are expressed on normal and tumoral corticotroph cells.
openaire   +4 more sources

Somatostatin receptor expression in parathyroid neoplasms

open access: yesEndocrine Connections, 2019
Introduction: Parathyroid carcinoma represents a rare cause of primary hyperparathyroidism. Distinguishing carcinoma from the benign tumors underlying primary hyperparathyroidism remains challenging.
Sara Storvall   +6 more
doaj   +1 more source

Somatostatin receptor imaging. the presence of somatostatin receptors in rheumatoid arthritis [PDF]

open access: yesArthritis & Rheumatism, 1994
AbstractObjective. To investigate the in vivo and in vitro expression of somatostatin receptors (SS‐R) on synovial membranes of patients with rheumatoid arthritis (RA).Methods. The joints of 14 consecutive patients with active RA, 4 patients with severe osteoarthritis (OA), and 30 control patients were studied.
P M, Vanhagen   +5 more
openaire   +2 more sources

Somatostatin Improved B Cells Mature in Macaques during Intestinal Ischemia-Reperfusion. [PDF]

open access: yesPLoS ONE, 2015
Intestinal ischemia-reperfusion has been taken as an important pathophysiological process for multiple organ dysfunctions in critical patients. Recent studies reported that dual expression programs of the B cells receptors and Toll-like receptors on B ...
Ling Liu   +6 more
doaj   +1 more source

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