Results 21 to 30 of about 57,406 (251)

False-positive 111 In-pentetreotide Uptake in Gastritis

open access: yesWorld Journal of Nuclear Medicine, 2013
111 In-pentetreotide [ 111 In-octreoscan] is the most widely used radiolabeled somatostatin analog for evaluating neuroendocrine tumor overexpression of somatostatin receptors.
Sharjeel Usmani, Alshaima Alshammari
doaj   +1 more source

Comparative study of somatostatin-human serum albumin fusion proteins and natural somatostatin on receptor binding, internalization and activation.

open access: yesPLoS ONE, 2014
Albumin fusion technology, the combination of small molecular proteins or peptides with human serum albumin (HSA), is an effective method for improving the medicinal values of natural small molecular proteins or peptides.
Ying Peng   +7 more
doaj   +1 more source

An expression signature of the angiogenic response in gastrointestinal neuroendocrine tumours: correlation with tumour phenotype and survival outcomes. [PDF]

open access: yes, 2013
BACKGROUND: Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) are heterogeneous with respect to biological behaviour and prognosis. As angiogenesis is a renowned pathogenic hallmark as well as a therapeutic target, we aimed to investigate the ...
A Couvelard   +47 more
core   +2 more sources

Competitive RT-PCR Strategy for Quantitative Evaluation of the Expression of Tilapia (Oreochromis niloticus) Growth Hormone Receptor Type I

open access: yesBiological Procedures Online, 2009
Quantization of gene expression requires that an accurate measurement of a specific transcript is made. In this paper, a quantitative reverse transcription-polymerase chain reaction (RT-PCR) by competition for tilapia growth hormone receptor type I is ...
Rodríguez-Mallon Alina   +5 more
doaj   +3 more sources

Activation of Muscarinic Acetylcholine Receptor Subtype 4 is Essential for Cholinergic Stimulation of Gastric Acid Secretion - Relation To D Cell/Somatostatin -

open access: yesFrontiers in Pharmacology, 2016
Background/Aim: Muscarinic acetylcholine receptors exist in five subtypes (M1~M5), and they are widely expressed in various tissues to mediate diverse autonomic functions, including gastric secretion.
Koji Takeuchi   +4 more
doaj   +1 more source

The somatostatinergic system in the mammalian cochlea

open access: yesBMC Neuroscience, 2011
Background Little is known about expression and function of the somatostatinergic system in the mammalian cochlea. We have previously shown that somatostatin administration may have a protective effect on gentamicin-induced hair cell loss. In this study,
Kapfhammer Josef P   +5 more
doaj   +1 more source

A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation. [PDF]

open access: yesPLoS ONE, 2012
The newly developed multireceptor somatostatin analogs pasireotide (SOM230), octreotide and somatoprim (DG3173) have primarily been characterized according to their binding profiles.
Andrea Kliewer   +4 more
doaj   +1 more source

Human Pancreas GH-Releasing Factor Analog Restores High-Amplitude GH Pulses in CNS Lesion-Induced GH Deficiency [PDF]

open access: yes, 1983
Lesions of the ventromedial-arcuate (VMH-ARC) region of the hypothalamus result in impaired growth accompanied by a marked suppression in spontaneous GH secretory bursts. We studied the effects of an analog of the recently characterized human pancreas GH-
Eikelboom, Rudy   +2 more
core   +2 more sources

Somatostatin and somatostatin receptors in Cushing's disease [PDF]

open access: yesMolecular and Cellular Endocrinology, 2008
Cushing's disease is caused by an ACTH secreting pituitary adenoma. Surgery is the treatment of choice and cure rates between 60 and 90% are reported. For patients in which surgery fails, effective medical treatment options are needed. Somatostatin (SS) receptors (sst) are expressed on normal and tumoral corticotroph cells.
openaire   +4 more sources

Somatostatin receptors in human adrenal gland tumors--immunohistochemical study.

open access: yesFolia Histochemica et Cytobiologica, 2008
Somatostatin receptors subtypes (SSTR 1-5) were demonstrated in surgically obtained adrenal gland tumors by means of immunohistochemistry (IHC). Results of the present study demonstrate that somatostatin receptors are expressed in adrenal tumors in a ...
Tomasz Stepień   +3 more
doaj   +1 more source

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