Results 51 to 60 of about 56,822 (196)
Focal Spot, Fall/Winter 1993 [PDF]
, 1993 https://digitalcommons.wustl.edu/focal_spot_archives/1065/thumbnail ...
core +1 more source
Case Reports in Oncology, 2016 Medical treatment of meningiomas is reserved for cases in which surgery and radiotherapy have failed. Given that a high percentage of meningiomas express somatostatin receptors, treatment with somatostatin analogues has been proposed.
Ana Ortolá Buigues +3 more
doaj +1 more source
A computational study of somatostatin subtype-4 receptor agonist binding
SN Applied Sciences, 2022 The somatostatin subtype-4 receptor (sst4) is highly expressed in neocortical and hippocampal areas, which are affected by amyloid beta accumulation. Sst4 agonists enhance downstream activity of amyloid beta peptide catabolism through neprilysin and may ...
Olivia Slater, Maria Kontoyianni
doaj +1 more source
Pituitary somatostatin receptor signaling [PDF]
Trends in Endocrinology & Metabolism, 2010 Somatotropin-release inhibitory factor (SRIF) is a major regulator of pituitary function, mostly inhibiting hormone secretion and to a lesser extent pituitary cell growth. Five SRIF receptor subtypes (SSTR1-5) are ubiquitously expressed G-protein coupled receptors.
Anat, Ben-Shlomo, Shlomo, Melmed
openaire +2 more sources
Frontiers in Cellular Neuroscience, 2023 GABAA receptors present in extrasynaptic areas mediate tonic inhibition in hippocampal neurons regulating the performance of neural networks. In this study, we investigated the effect of NMDA-induced plasticity on tonic inhibition in somatostatin- and ...
Marcin Wyroślak +2 more
doaj +1 more source
On the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation [PDF]
, 2013 The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the Central Nervous System and the peripheral nociceptors has become of increasing interest.
Agnati, Luigi F +6 more
core +3 more sources
Frontiers in Behavioral Neuroscience, 2019 Somatostatin (SOM) and somatostatin receptors (SSTR1–4) are present in all olfactory structures, including the olfactory bulb (OB), where SOM modulates physiological gamma rhythms and olfactory discrimination responses.
Sonia Nocera +14 more
doaj +1 more source
Diagnostics, 2021 We describe the case of a 74-year-old female patient previously treated with radiation therapy for a meningioma of the skull base and with surgery for a right tympanic paraganglioma.
Giorgio Treglia +5 more
doaj +1 more source
A receptor-based analysis of local ecosystems in the human brain. [PDF]
, 2017 BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core +1 more source
Current Issues in Molecular BiologySomatostatin is a peptide that plays a variety of roles such as neurotransmitter and endocrine regulator; its actions as a cell regulator in various tissues of the human body are represented mainly by inhibitory effects, and it shows potent activity ...
Argyrios Periferakis +12 more
doaj +1 more source