Results 31 to 40 of about 1,664 (165)

Budget Impact Analysis of Biosimilar Products in Spain in the Period 2009–2019

Pharmaceuticals, 2021
Since the first biosimilar medicine, Omnitrope® (active substance somatropin) was approved in 2006, 53 biosimilars have been authorized in Spain. We estimate the budget impact of biosimilars in Spain from the perspective of the National Health System ...
Manuel García-Goñi, Isabel Río-Álvarez, David Carcedo, Alba Villacampa   +3 more
doaj   +1 more source

Investigating thermally induced aggregation of Somatropin- new insights using orthogonal techniques

, 2023
Three orthogonal techniques were used to provide new insights into thermally induced aggregation of the therapeutic protein Somatropin at pH 5.8 and 7.0.
Sintorn, Ida-Maria,, Lidayová, Kristina,, Leeman, Mats, Mats Leeman, Nilsson, Lars,, Nylander, Tommy, Amanda Västberg, Ulla Elofsson, Elofsson, Ulla,, Lars Nilsson, Sjögren, Helen,, Nylander, Tommy,, Sintorn, Ida Maria, Hans Bolinsson, Helen Sjögren, Marie Wahlgren, Sejwal, Kushal,, Tommy Nylander, Västberg, Amanda, Lidayová, Kristina, Bolinsson, Hans,, Västberg, Amanda,, Sejwal, Kushal, Leeman, Mats,, Kristina Lidayová, Nilsson, Lars, Wahlgren, Maria,, Ida-Maria Sintorn, Sjögren, Helen, Wahlgren, Marie, Elofsson, Ulla, Kushal Sejwal, Bolinsson, Hans, Sintorn, Ida Maria,, Lund University., Wahlgren, Marie,   +35 more
core   +2 more sources

Sever’s Disease in a Patient Receiving Growth Hormone with no Causative Relation [PDF]

Journal of Clinical and Diagnostic Research, 2018
Growth Hormone (GH) shows its main effect on bones and muscle tissues. There are reports of orthopaedic complications including carpal tunnel syndrome, Legg-Calve-Perthe’s disease, scoliosis, and slipped capital femoral epiphysis with GH use in the ...
Erdal Kurnaz, Senay Savas-Erdeve, Zehra Aycan, Semra Çetinkaya   +3 more
doaj   +1 more source

ACAN Pathogenic Variant as a Cause of Short Stature

Portuguese Journal of Pediatrics, 2023
Pathogenic variants of the aggrecan (ACAN) gene have been associated with a wide spectrum of growth modifications ranging from idiopathic short stature to severe skeletal dysplasia.
Diana Reis Monteiro, Miguel Leão, Maria Adriana Rangel, Rosa Arménia Campos, Ana Luísa Leite   +4 more
doaj   +1 more source

604. Safety and Efficacy of Oxandrolone vs Somatropin/Testosterone in Adult Patients with Severe Burns [PDF]

J Burn Care Res
Introduction: Historically oxandrolone, a testosterone analogue, was used to prevent muscle breakdown in severe burn patients and was shown to reduce length of stay (LOS) and increase weight gain.
Walroth, Todd A., Terrell, Teana, Dine, Serena, Thomas, Ashley E., Lautenslager, Lauren A., Thomas, Elaina, Spera, Leigh J., Hagen, McKensie, Boyd, Allison N.   +8 more
europepmc   +2 more sources

Designing a Personalized Digital Patient Support Program for Patients Treated With Growth Hormone: Key Design Considerations

Journal of Medical Internet Research, 2020
BackgroundRecombinant human growth hormone treatment can optimize growth potential; however, optimal outcomes are not always achieved for several reasons, including poor adherence.
Malik, Sumaira, Moloney, Clare, Koledova, Ekaterina, Reston, Jonathan, Weinman, John   +4 more
doaj   +1 more source

Assessment of Parental Satisfaction with the Treatment of Human Recombinant Growth Hormone in Children with Hypopituitarism

Pielęgniarstwo Neurologiczne i Neurochirurgiczne, 2021
Introduction. Growth depends on genetic, metabolic and also hormonal factors. Growth depends on health, the supply of nutrients and a properly functioning nervous system.
Lech Grzelak, Anna Wiśniewska
doaj   +1 more source

Development of Competitive ELISAs Suitable for Detection of Recombinant Human Growth Hormone in Illegal Nutritional Supplements. [PDF]

J Anal Methods Chem
The use of human growth hormone (hGH) by athletes remains widespread despite being banned by the World Anti‐Doping Agency (WADA). Current commercial ELISA kits for the determination of hGH are predominantly based on the sandwich format of this method, which allows the analysis of the whole hGH molecules, but not their fragments.
Karamonová L, Procházková B, Volný M, Nemeškalová A, Sýkora D, Kuchař M, Fukal L, Holubová B.   +7 more
europepmc   +2 more sources

Peculiarities of Lipid Spectrum in Children with short stature [PDF]

Саратовский научно-медицинский журнал, 2010
The research goal is to examine the lipid spectrum and to evaluate the effectiveness of somatropin therapy for correcting metabolic disorders in children with various forms of short stature.
Kopytina E.V.
doaj  

Simultaneous electrochemical investigation and detection of two glucocorticoids; interactions with human growth hormone, somatropin

Results in Chemistry, 2022
In the present work, the simultaneous determination of dexamethasone (DXM) and hydrocortisone (HYD) is described by the use of a nano-porous glassy carbon electrode (GCE), prepared via an electrochemical treatment.
Giti Paimard, Mojtaba Shamsipur, Mohammad Bagher Gholivand, Mohsen Shahlaei   +3 more
doaj   +1 more source