Results 101 to 110 of about 53,966 (229)
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Background Effective adjuvant treatments in resected or ablated hepatocellular carcinoma (HCC) were elusive over the preceding decades. Recently, immune checkpoint inhibitors (ICIs) have been investigated in the adjuvant setting, with conflicting results. Methods A systematic literature search was conducted in multiple databases.
Erman Akkus, Hatime Arzu Yaşar
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, accounting for up to 80% of all cases. Most patients present at an advanced stage and are unsuitable for curative treatments. In the past 5 years, immunotherapy combination has superseded tyrosine kinase inhibitors (TKI) as the standard first‐line therapy for ...
Landon L. Chan +2 more
wiley +1 more source
Analysis of SWI Complex Subunits in 69 Cases of TTF‐1 Negative Non‐Small Cell Lung Carcinoma
Diagnostic Cytopathology, Volume 54, Issue 4, Page 278-284, April 2026.ABSTRACT Non‐small cell lung carcinomas, not otherwise specified (NSCLC‐NOS) with a specific signature including high‐grade hepatoid/clear cell morphology, negative lung panel mutational analysis, negative TTF‐1/Napsin A staining can be reported as a morphologic variant of an aggressive carcinoma with loss of one of the subunits of the SWI/SNF ...
Ramin Zargham +2 more
wiley +1 more source
International Journal of Cancer, Volume 158, Issue 7, Page 1821-1835, 1 April 2026.What's new? Most patients with ovarian cancer (OC) relapse after first‐line chemotherapy, and prognosis with second‐line treatment depends largely on the platinum‐free interval. However, reliable biomarkers to predict response to second‐line therapy remain lacking.
Muhammad Habiburrahman +7 more
wiley +1 more source
Journal of Clinical Apheresis, Volume 41, Issue 2, April 2026.ABSTRACT Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy, and 5%–20% of newly diagnosed patients present with hyperleukocytosis (HL). HL, most often defined as WBC > 100 000/μL, is a hematologic emergency associated with severe complications, early mortality, and poor prognosis, requiring immediate intervention.
Vojtech Latal +10 more
wiley +1 more source
Molecular Carcinogenesis, Volume 65, Issue 4, Page 523-536, April 2026.ABSTRACT Canine hepatocellular carcinoma (HCC) requires further molecular characterization to identify diagnostic and therapeutic targets, and to establish whether dogs with this condition can model the human disease. Accordingly, we aimed to identify differentially expressed genes (DEGs) in canine HCC and evaluate cross‐species transcriptomic ...
Mohammad Arif +8 more
wiley +1 more source
Study on the effect of Ursolic acid on liver cancer cells using z-vad-fmk and ROS inhibitors. [PDF]
CytotechnologyXu M +6 more
europepmc +1 more source
Selinexor enhances the sensitivity of hepatocellular carcinoma cells to sorafenib by regulating the BAX/Bcl-2/PUMA apoptotic pathway and the XPO1/p27 cell cycle pathway. [PDF]
Front OncolDu S +8 more
europepmc +1 more source
AI‐assisted design of a VEGFR2 agonistic peptide that promotes angiogenesis and wound repair
Protein Science, Volume 35, Issue 4, April 2026.Abstract Vascular endothelial growth factor (VEGF) serves as a principal regulator of neovascularization and is essential for vascular regeneration. In this study, we identified and evaluated VEGF Mimetic Peptide3 (VMP3), a novel synthetic peptide developed as a potential VEGFR‐2/VEGF‐A modulator.
Farzana Yasmeen +7 more
wiley +1 more source
Nutrient Restriction Improves the Therapeutic Efficacy of Sorafenib by Inducing Ferroptosis via the NRF2/HO-1/GPX4 Pathway in Hepatocellular Carcinoma. [PDF]
J Hepatocell CarcinomaChen X +6 more
europepmc +1 more source