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Estudo do efeito e do mecanismo de ação de isoflavonas naturais com potencial efeito antidiabético [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2014.A diabetes é uma doença crônica que afeta milhões de pessoas no mundo.
Altenhofen, Delsi
core
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley +1 more source
ABSTRACT Isoflavone synthase (IFS), a cytochrome P450 monooxygenase of the CYP93C subfamily, catalyzes the conversion of flavanones into isoflavones, the first committed step in the biosynthesis of isoflavonoid phytoalexins. In pea (Pisum sativum L.), the phytoalexin pisatin plays a pivotal role in defense against pathogens.
Muhammad Sufyan Tahir +4 more
wiley +1 more source
ABSTRACT With the growing global population and change in consumers' lifestyles, there is a pressing need for sustainable, safe, and nutritious sources of protein. Alternative proteins, like plant‐based meat supplemented with pea protein, offer a promising source; however, knowledge of their application, allergenicity, and safety is limited, and the ...
Ahmadullah Zahir +6 more
wiley +1 more source
ABSTRACT Guava is known for being rich in vitamin C, fiber, and polyphenol compounds, and soy flour is an abundant source of plant‐based protein and minerals. The investigation focused on the formulation of biscuits enriched with antioxidants and nutrients, using guava and soy flour, to meet the increasing demand for functional meals that provide ...
Md. Jaynal Abedin +4 more
wiley +1 more source
Risk of Breast Cancer Associated with Intake of Soy Isoflavones.
Risk of Breast Cancer Associated with Intake of Soy Isoflavones.
Heidi Fritz (198213) +11 more
core +1 more source
Dietary soy and isoflavone intake and mortality in Korean adults: a prospective cohort study
BackgroundThe association between dietary soy and isoflavone intake and mortality remains inconclusive. This study aimed to examine the relationships of dietary intakes of isoflavones, soy protein, and soy foods with all-cause, cancer, and cardiovascular
Sihan Song +5 more
doaj +1 more source
Shotgun metagenomic sequencing was used to characterize the functional potential of the Allium ampeloprasum rhizosphere microbiome under chemical fertilizer (G1), biofertilizer (G2), and unfertilized (Bulk) soil (G3) management practices. This study revealed that different fertilization regimes altered microbial functional profiles.
Oluwaseun Emmanuel Shittu +2 more
wiley +1 more source
Inhibition of lipoxygenase by soy isoflavones: evidence of isoflavones as redox inhibitors.
Hydroperoxides, the products of lipoxygenase mediated pathways, play a major role in the manifestation of chronic inflammatory diseases. Soy isoflavones act as antioxidants due to their ability to scavenge free radicals.
Sridevi Annapurna, Singh +2 more
core
Encephalopathy: Cause, Pathogenesis, and Treatment
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source

