Results 1 to 10 of about 28,088 (146)

The association between sPD-1 levels versus liver biochemistry and viral markers in chronic hepatitis B patients: a comparative study of different sPD-1 assays [PDF]

Virology Journal, 2022
Background Soluble programmed death-1 (sPD-1) is a novel immune markers and possibly predictive of chronic hepatitis B (CHB) outcome. However, results were inconsistent by different ELISA kits.
Wen-Juei Jeng, Chien-Hung Chen, Yi-Wen Wang, Mei-Hung Pan, Chia-Wei Lin, Chun-Yen Lin, Hwai-I Yang   +6 more
doaj   +4 more sources

Characterization of alternative sPD-1 isoforms reveals that ECD sPD-1 signature predicts an efficient antitumor response [PDF]

Communications Biology
Soluble PD-1 is a dissociated form of membrane PD-1 broadly present in cancer, infections, or autoimmune diseases. However, the clinical significance of sPD-1 remains controversial due to the uncertainty of its isoforms, origin, and production mechanism.
Ping Hou, Li Hu, Junrong Zhang, Xiaoyan Zhou, Yonglei Xiao, Lijun Li, Qiongwen Wu, Jing Liu, Yuhong Lin, Ling Chen   +9 more
doaj   +4 more sources

Nanobubbles Containing sPD-1 and Ce6 Mediate Combination Immunotherapy and Suppress Hepatocellular Carcinoma in Mice [PDF]

International Journal of Nanomedicine, 2021
Yandi Tan,1,* Shiqi Yang,1,* Yao Ma,2 Jinlin Li,1 Qian Xie,1 Chaoqi Liu,1 Yun Zhao1 1Medical College of China Three Gorges University, Yichang, Hubei, People’s Republic of China; 2Department of Ultrasonography, Yichang Central People’s ...
Tan Y, Yang S, Ma Y, Li J, Xie Q, Liu C, Zhao Y   +6 more
doaj   +5 more sources

An investigation of the relationship between sPD-1, sPD-L1 and severe pneumonia patients admitted to ICU and its clinical significance [PDF]

Frontiers in Medicine
BackgroundSoluble programmed cell death 1 (sPD-1) and its ligand (sPD-L1) have emerged as potential biomarkers for early identification and risk stratification in patients with severe pneumonia (SP). However, there is a lack of robust laboratory evidence
Zirong Gao, Zirong Gao, Yanhui Lu, Shanshan Yu, Bao Fu   +4 more
doaj   +4 more sources

Ultrasound-Mediated Co-Delivery of miR-34a and sPD-1 Complexed with Microbubbles for Synergistic Cancer Therapy [PDF]

Cancer Management and Research, 2020
Yu-e Qin,* Wen-fan Tang,* Yun Xu, Fu-rong Wan, Ai-hua Chen Department of Gynecology and Obstetrics, The People’s Hospital of China Three Gorges University/The First People’s Hospital of Yichang, Yichang 443000, Hubei, People’s Republic ...
Qin Y, Tang W, Xu Y, Wan F, Chen A
doaj   +5 more sources

Soluble programmed death molecule 1 (sPD-1) as a predictor of interstitial lung disease in rheumatoid arthritis. [PDF]

BMC Immunol, 2021
Abstract Background Previous studies have indicated that the programmed death molecule 1 (PD-1) signaling pathway may play a key role in rheumatoid arthritis (RA). However, the pathogenesis of rheumatoid arthritis-related interstitial lung disease (RA-ILD) is not clear.
Xu L, Jiang L, Nie L, Zhang S, Liu L, Du Y, Xue J.   +6 more
europepmc   +6 more sources

Role of sPD-1 and sPD-Ls in the pathogenesis of connective tissue disease. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023
Membrane-bound programmed cell death-1 (mPD-1) and membrane-bound programmed cell death-ligands (mPD-Ls) have soluble forms, which are soluble programmed cell death-1 (sPD-1) and soluble programmed cell death-ligands (sPD-Ls) [including soluble programmed cell death-ligand 1 (sPD-L1) and soluble programmed cell death-ligand 2 (sPD-L2)].
He H, He X, Zhou M, Tang Y, Dai L, Xie Z, Wang Y, Xie C.   +7 more
europepmc   +3 more sources

Soluble programmed death-1 (sPD-1) and programmed death ligand 1 (sPD-L1) as potential biomarkers for the diagnosis and prognosis of glioma patients [PDF]

Journal of Medical Biochemistry, 2020
Background: This study aimed at investigating the feasibility of testing for soluble programmed death-1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in serum samples of glioma patients and to evaluate the diagnostic and prognostic value of ...
Liu Shujun, Zhu Yadi, Zhang Chenxi, Liu Jiajia, Lv Hong, Zhang Guojun, Kang Xixiong   +6 more
doaj   +2 more sources

Can sPD-1 and sPD-L1 Plasma Concentrations Predict Treatment Response among Patients with Extraparenchymal Neurocysticercosis? [PDF]

Pathogens, 2023
Extraparenchymal neurocysticercosis (EP-NC) is a chronic, potentially life-threatening disease that responds poorly to initial anthelmintic drug therapy. A depressed specific reactivity of peripheral lymphocytes and an increased level of specific Tregs accompanies EP-NC.
Toledo A, Fragoso G, Carrillo-Mezo R, Romo ML, Sciutto E, Fleury A.   +5 more
europepmc   +4 more sources

Association of plasma sPD‐1 and sPD‐L1 with disease status and future relapse in AQP4‐IgG (+) NMOSD [PDF]

Annals of Clinical and Translational Neurology
Objective Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune‐mediated disorder with aquaporin 4‐immunoglobulin G (AQP4‐IgG) in most settings. Soluble programmed death‐1 (sPD‐1) and soluble programmed death ligand 1 (sPD‐L1) play key roles in
Jia Liu, Xi Shao, Jingya Fan, Ying Wang, Yuanbo Cao, Guojun Tan, Kazuo Sugimoto, Bin Li, Zhen Jia   +8 more
doaj   +2 more sources