Results 31 to 40 of about 21,277,776 (188)

Soluble forms of PD-L1 and PD-1 as prognostic and predictive markers of sunitinib efficacy in patients with metastatic clear cell renal cell carcinoma

OncoImmunology, 2020
Metastatic clear cell renal cell carcinoma (mccRCC) benefits from several treatment options in the first-line setting with VEGFR inhibitors and/or immunotherapy including anti-PD-L1 or anti-PD1 agents.
Christopher Montemagno, Anais Hagege, Delphine Borchiellini, Brice Thamphya, Olivia Rastoin, Damien Ambrosetti, Juan Iovanna, Nathalie Rioux-Leclercq, Camillio Porta, Sylvie Negrier, Jean-Marc Ferrero, Emmanuel Chamorey, Gilles Pagès, Maeva Dufies   +13 more
doaj   +1 more source

Skin picking treatment with the Rothbaum cognitive behavioral therapy protocol: a randomized clinical trial [PDF]

Brazilian Journal of Psychiatry, 2020
Introduction: Although behavioral therapies can effectively treat skin picking disorder (SPD), there is no standardized treatment for improving SPD and its comorbidities and there is no group intervention option.
Alice C.M. Xavier, Camila M.B. de Souza, Luís H.F. Flores, Mariane B. Bermudez, Renata M.F. Silva, Ariadne C. de Oliveira, Carolina B. Dreher   +6 more
doaj   +1 more source

Soluble PD-1: Predictive, Prognostic, and Therapeutic Value for Cancer Immunotherapy

Frontiers in Immunology, 2020
Programmed death protein 1 (PD-1) interaction with PD-L1 deliver immunosuppressive environment for tumor growth, and its blockade with directed monoclonal antibodies (anti-PD-1/anti-PD-L1) has shown remarkable clinical outcome.
Muhammad Khan, Muhammad Khan, Zhihong Zhao, Sumbal Arooj, Sumbal Arooj, Yuxiang Fu, Guixiang Liao   +6 more
doaj   +1 more source

Circulating level of sPD-1 and PD-1 genetic variants are associated with hepatitis B infection and related liver disease progression [PDF]

International Journal of Infectious Diseases, 2022
Programmed cell death-1 (PD-1) variants and circulating level of soluble PD-1 are associated with susceptibility to malignant and infectious disease. This study aimed to examine the association of PD-1.5 and PD-1.9 variants, and plasma sPD-1 level with hepatitis B virus (HBV) infection and disease progression.The study cohort consisted of adults ...
Pham Thi Minh Huyen, Dang Thi Ngoc Dung, Peter Johann Weiß, Phan Quoc Hoan, Dao Phuong Giang, Ngo Thi Uyen, Nguyen Van Tuan, Ngo Tat Trung, Thirumalaisamy P. Velavan, Le Huu Song, Nghiem Xuan Hoan   +10 more
openaire   +3 more sources

WITHDRAWN: Decreased plasma sPD-1 level correlates with disease activity in systemic juvenile idiopathic arthritis patients [PDF]

, 2020
Abstract Objectives: Soluble programmed death-1 (sPD-1) and its ligand (sPD-L1) take part in some autoimmune diseases. Little is known about its role in systemic idiopathic arthritis (sJIA). The study aimed to explore the sPD-1 and sPD-L1 levels in sJIA patiens and elucidate their underlying immunomodulatory mechanisms.
Li Cai, Chenxing Zhang, Ji Wu, Wei Zhou, Tongxin Chen   +4 more
openaire   +2 more sources

Task 1: Science for Peace and Development – Summary Results of SPD Summer 2018

, 2018
Report of summary results for Science for Peace and Development Initiatives launched during year 2017 to year 2018 by Task 1: SPD ...
T1: SPD Team
core   +1 more source

Soluble Programmed Cell Death Protein 1 and Its Ligand: Potential Biomarkers to Predict Acute Kidney Injury After Surgery in Critically Ill Patients

Journal of Inflammation Research, 2022
Jingyi Wang, Xi Zheng, Yijia Jiang, Huimiao Jia, Xiaocui Shi, Yue Han, Qingping Li, Wenxiong Li Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People’s Republic of ChinaCorrespondence: Wenxiong Li, Surgical ...
Wang J, Zheng X, Jiang Y, Jia H, Shi X, Han Y, Li Q, Li W   +7 more
doaj  

Biological Characteristics and Clinical Significance of Soluble PD-1/PD-L1 and Exosomal PD-L1 in Cancer

Frontiers in Immunology, 2022
The immune checkpoint pathway consisting of the cell membrane-bound molecule programmed death protein 1 (PD-1) and its ligand PD-L1 has been found to mediate negative regulatory signals that effectively inhibit T-cell proliferation and function and ...
Mengke Niu, Yiming Liu, Ming Yi, Dechao Jiao, Kongming Wu, Kongming Wu   +5 more
doaj   +1 more source

21. Oktober 1945 – Gemeinsame Kundgebung von SPD und KPD

, 2018
1
Sywottek, Jutta
core   +1 more source

Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation

Biology Open, 2016
Centrosomes are major microtubule-organizing centers composed of centrioles surrounded by an extensive proteinacious layer called the pericentriolar material (PCM).
Oliver Wueseke, David Zwicker, Anne Schwager, Yao Liang Wong, Karen Oegema, Frank Jülicher, Anthony A. Hyman, Jeffrey B. Woodruff   +7 more
doaj   +1 more source