Results 41 to 50 of about 21,277,776 (188)

Baseline plasma levels of soluble PD-1, PD-L1, and BTN3A1 predict response to nivolumab treatment in patients with metastatic renal cell carcinoma: a step toward a biomarker for therapeutic decisions

OncoImmunology, 2020
Despite a proportion of renal cancer patients can experiment marked and durable responses to immune-checkpoint inhibitors, the treatment efficacy is widely variable and identifying the patient who will benefit from immunotherapy remains an issue.
Lorena Incorvaia, Daniele Fanale, Giuseppe Badalamenti, Camillo Porta, Daniel Olive, Ida De Luca, Chiara Brando, Mimma Rizzo, Carlo Messina, Mattia Rediti, Antonio Russo, Viviana Bazan, Juan Lucio Iovanna   +12 more
doaj   +1 more source

A systematic exploration reveals the potential of spermidine for hypopigmentation treatment through the stabilization of melanogenesis-associated proteins

Scientific Reports, 2022
Spermidine (SPD), a polyamine naturally present in living organisms, is known to prolong the lifespan of animals. In this study, the role of SPD in melanogenesis was investigated, showing potential as a pigmenting agent.
Sofia Brito, Hyojin Heo, Byungsun Cha, Su-Hyun Lee, Sehyun Chae, Mi-Gi Lee, Byeong-Mun Kwak, Bum-Ho Bin   +7 more
doaj   +1 more source

SPD Members Survey 1991

, 1995
Judgement on the SPD by its members. Topics: Length of membership in the SPD as well as in the local committee; contact or cause for personally joining the party; manner of first contact on the part of the party after joining; evaluation of selected ...
SPD-Parteivorstand, Bonn
core   +1 more source

Prognostic role of soluble PD-1 and BTN2A1 in overweight melanoma patients treated with nivolumab or pembrolizumab: finding the missing links in the symbiotic immune-metabolic interplay

Therapeutic Advances in Medical Oncology, 2023
Individual response to immune checkpoint inhibitors (ICIs) is currently unpredictable in patients with melanoma. Recent findings highlight a striking improvement in the clinical outcomes of overweight/obese patients treated with ICIs, which seems driven,
Lorena Incorvaia, Gaetana Rinaldi, Giuseppe Badalamenti, Alessandra Cucinella, Chiara Brando, Giorgio Madonia, Alessia Fiorino, Angela Pipitone, Alessandro Perez, Federica Li Pomi, Antonio Galvano, Valerio Gristina, Nadia Barraco, Marco Bono, Tancredi Didier Bazan Russo, Francesca Toia, Adriana Cordova, Daniele Fanale, Antonio Russo, Viviana Bazan   +19 more
doaj   +1 more source

SPD-rsfMRI-NEU-ZS.zip

, 2018
We have MRI images of 18 Schizotypal Personality Disorder (SPD) and 18 healthy controls.
Shouliang Qi (5510786)
core   +1 more source

Soluble PD-L1 changes in advanced non-small cell lung cancer patients treated with PD-1 inhibitors: an individual patient data meta-analysis

Frontiers in Immunology, 2023
IntroductionCurrently, first-line immune checkpoint inhibitors (ICIs), including programmed cell death protein-1 (PD-1) inhibitors, are utilized as monotherapy in advanced non-small cell lung cancer (NSCLC) patients with high programmed death ligand-1 ...
Takashi Shimizu, Takashi Shimizu, Eisuke Inoue, Ryotaro Ohkuma, Ryotaro Ohkuma, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada, Satoshi Wada, Satoshi Wada, Satoshi Wada, Satoshi Wada   +11 more
doaj   +1 more source

Role of soluble programmed death-1 (sPD-1) and sPD-ligand 1 in patients with cystic echinococcosis

Experimental and Therapeutic Medicine, 2015
The programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) signaling pathway is a negative regulatory mechanism that inhibits T cell proliferation and cytokine production. Soluble PD-1 (sPD-1) and soluble PD-L1 (sPD-L1), are also involved in regulation of the PD-1/PD-L1 signaling pathway.
Yanhua, Li, Yunfeng, Xiao, Mingquan, Su, Rong, Zhang, Jianbing, Ding, Xiaoke, Hao, Yueyun, Ma   +6 more
openaire   +3 more sources

SPD Party Office-Holder Survey 1991

, 1995
Judgement on the SPD by party office-holders in the party. Topics: Length of membership in the SPD as well as in local committee; contact or cause for personally joining the party; manner of first contact on the part of the party after joining ...
SPD-Parteivorstand, Bonn
core   +1 more source

Prognostic value of soluble programmed death-1 and soluble programmed death ligand-1 in severe traumatic brain injury patients

Scientific Reports
Patients with traumatic brain injury (TBI) frequently exhibit concomitant immunosuppression. In this study, we evaluated the predictive values of soluble programmed death-1 (sPD-1) and soluble programmed death ligand-1 (sPD-L1) in patients with severe ...
Lei Liu, Pengpeng Lan, Guiping Wu, Xiaojie Zhu, Hongfeng Shi, Yan Li, Ruili Li, Ling Zhao, Juan Xu, Min Xu   +9 more
doaj   +1 more source

Low Soluble Programmed Cell Death Protein 1 Levels After Allogeneic Stem Cell Transplantation Predict Moderate or Severe Chronic GvHD and Inferior Overall Survival

Frontiers in Immunology, 2021
Programmed cell death protein-1 (PD-1) is an inhibitory co-receptor required for regulating immune responsiveness and maintaining immune homeostasis.
Lambros Kordelas, Ulrike Buttkereit, Falko M. Heinemann, Peter A. Horn, Bernd Giebel, Dietrich W. Beelen, H. Christian Reinhardt, Vera Rebmann   +7 more
doaj   +1 more source