Results 71 to 80 of about 5,924,760 (360)

Antimicrobial drug use and resistance in Europe [PDF]

open access: yes, 2008
Our study confronts the use of antimicrobial agents in ambulatory care with the resistance trends of 2 major pathogens, Streptococcus pneumoniae and Escherichia coli, in 21 European countries in 2000–2005 and explores whether the notion that ...
Grundmann, Hajo   +8 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Design and Process Analysis of a Split-Gate Trench Power MOSFET With Bottom-Trench High-k Pillar Superjunction for Enhanced Performance

open access: yesIEEE Access
In this paper, we propose a simulation-based novel Split-Gate Trench MOSFET structure with an optimized fabrication process to enhance power efficiency, switching speed, and thermal stability for high-performance semiconductor applications.
Yunteng Jiang   +8 more
doaj   +1 more source

Analytical Models of Breakdown Voltage and Specific On-Resistance for Vertical GaN Unipolar Devices

open access: yesIEEE Access, 2019
In this paper, the analytical models of breakdown voltage design parameters and minimum specific on-resistance in vertical gallium nitride unipolar devices are proposed.
Haimeng Huang   +4 more
doaj   +1 more source

Reactive oxygen species production during non-specific elicitation, non-host resistance and field resistance expression in cultured tobacco cells. [PDF]

open access: yes, 2003
[Abstract]: We examined production of reactive oxygen species (ROS) and induction of cell death in tissue-cultured tobacco cells undergoing different disease resistance responses. A superoxide-dependent hypersensitive response occurs during both the race-
Sutherland, Mark W.   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Optimized 4H-SiC Trench MOS Barrier Schottky (TMBS) Rectifier

open access: yesIEEE Journal of the Electron Devices Society, 2018
This paper proposes an optimal 4H-silicon carbide trench MOS barrier Schottky (TMBS) Rectifier. The optimal structure of this rectifier is achieved by adding an N− wrapping region at the P+ shielding of the conventional TMBS structure ...
Ying Wang   +5 more
doaj   +1 more source

Age-specific expression of resistance to a neonicotinoid insecticide in the whitefly Bemisia tabaci

open access: yes, 2008
Neonicotinoid insecticides retain a crucial role within many chemical and integrated control strategies for the tobacco whitefly, Bemisia tabaci Gernnadius, in spite of the establishment of potent and widespread resistance in many areas.
Denholm, I.   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

An Improved 4H-SiC Trench MOS Barrier Schottky Diode With Lower On-Resistance

open access: yesIEEE Access, 2019
An improved 4H-SiC trench MOS barrier Schottky (TMBS) structure that can significantly reduce the specific on-resistance ( $R_{on,sp}$ ) is proposed in this paper.
Fei Cao   +5 more
doaj   +1 more source

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