Results 71 to 80 of about 4,724,107 (342)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An Improved 4H-SiC Trench MOS Barrier Schottky Diode With Lower On-Resistance

IEEE Access, 2019
An improved 4H-SiC trench MOS barrier Schottky (TMBS) structure that can significantly reduce the specific on-resistance (Ron,sp) is proposed in this paper.
Fei Cao, Meng-tian Bao, Xue Wu, Wen-Ju Wang, Cheng-Hao Yu, Ying Wang   +5 more
doaj   +1 more source

The politics of in/visibility: carving out queer space in Ul'yanovsk [PDF]

, 2012
<p>In spite of a growing interest within sexualities studies in the concept of queer space (Oswin 2008), existing literature focuses almost exclusively on its most visible and territorialised forms, such as the gay scene, thus privileging Western ...
Bell D., Binnie J., Brewer J. D., Brown M. P., Castells M., Charles M., Chasin A., Duberman M., Essig L., Foucault M., Francesca Stella, Gdaniec C., Greenwood P., Gurova O., Human Rights Watch, Human Rights Watch &, ILGA-Europe, Konitzer-Smirnov A., Krongauz E., Lomovtsev E., Magovedova M., Manalansan M. F. I., Moran L. J., Moscow Helsinki Group, Nartova N., Nartova N., Omel'chenko E., Omel'chenko E., Pile S., Pilkington H., Pilkington H., Richardson D., Sedgwick E. K., Stella F., Stella F., Voronkov V., Weston K., Zelenina G.   +37 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An Optimized 4H-SiC Trench MOS Barrier Schottky (TMBS) Rectifier

IEEE Journal of the Electron Devices Society, 2018
This paper proposes an optimal 4H-silicon carbide trench MOS barrier Schottky (TMBS) Rectifier. The optimal structure of this rectifier is achieved by adding an N− wrapping region at the P+ shielding of the conventional TMBS structure ...
Ying Wang, Wen-Ju Wang, Cheng-Hao Yu, Yi-Fei Huang, You-Lei Sun, Jian-Xiang Tang   +5 more
doaj   +1 more source

The distribution of plasmids that carry virulence and resistance genes in Staphylococcus aureus is lineage associated. [PDF]

, 2012
BACKGROUND: Staphylococcus aureus is major human and animal pathogen. Plasmids often carry resistance genes and virulence genes that can disseminate through S. aureus populations by horizontal gene transfer (HGT) mechanisms. Sequences of S.
Lindsay, JA, McCarthy, AJ
core   +2 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Antifungal Resistance: Specific Focus on Multidrug Resistance in Candida auris and Secondary Azole Resistance in Aspergillus fumigatus

Journal of Fungi, 2018
Antifungal resistance is a topic of concern, particularly for specific fungal species and drugs. Among these are the multidrug-resistant Candida auris and azole-resistant Aspergillus fumigatus. While the knowledge on molecular mechanisms of resistance is
Sevtap Arikan-Akdagli, Mahmoud Ghannoum, Jacques F. Meis   +2 more
doaj   +1 more source