Results 1 to 10 of about 101,709 (231)

Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage [PDF]

Asian Journal of Andrology, 2015
Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan, Helen Clarke, Rachel Cutting, Jane Saxton, Sarah Waite, William Ledger, Tinchiu Li, Allan A Pacey   +7 more
doaj   +5 more sources

Evaluation of Sperm DNA Fragmentation Using Two Different Methods: TUNEL via Fluorescence Microscopy, and Flow Cytometry

Medicina, 2023
Background and Objectives: Sperm DNA fragmentation refers to any break in one or both of the strands of DNA in the head of a sperm. The most widely used methodologies for assessing sperm DNA fragmentation are the sperm chromatin structure assay (SCSA ...
Katerina Chatzimeletiou, Alexandra Fleva, Theodoros-Thomas Nikolopoulos, Maria Markopoulou, Glykeria Zervakakou, Kyriakos Papanikolaou, George Anifandis, Anastasia Gianakou, Grigoris Grimbizis   +8 more
doaj   +2 more sources

Sperm chromatin dispersion test before sperm preparation is predictive of clinical pregnancy in cases of unexplained infertility treated with intra-uterine insemination and induction with clomiphene citrate [PDF]

Frontiers in Medicine, 2016
Background/Aims: A large proportion of men with normal sperm results as analyzed using conventional techniques have fragmented DNA in their spermatozoa.
FRANK W.R.C. VANDEKERCKHOVE, ILSE DE CROO, JAN GERRIS, ETIENNE VANDEN ABBEEL, PETRA DE SUTTER   +4 more
doaj   +4 more sources

Sperm DNA Fragmentation in Reproductive Medicine: A Review

Journal of Human Reproductive Sciences, 2022
Approximately 15% of the world's couples suffer from infertility during their reproductive period of which the male factor is responsible for 50% of cases.
A. Alahmar, Rajender Singh, A. Palani
semanticscholar   +4 more sources

Sperm DNA Fragmentation: A New Guideline for Clinicians

The World Journal of Men's Health, 2020
Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases of spermatogenesis, which imparts compaction and protects the genetic ...
A. Agarwal, A. Majzoub, S. Baskaran, M. P. Selvam, C. Cho, R. Henkel, R. Finelli, K. Leisegang, P. Sengupta, C. Barbăroșie, N. Parekh, M. Alves, Edmund Y Ko, Mohamed Arafa, N. Tadros, R. Ramasamy, P. Kavoussi, R. Ambar, M. Kuchakulla, K. Robert, C. Iovine, D. Durairajanayagam, S. Jindal, R. Shah   +23 more
semanticscholar   +6 more sources

Study Protocol: Effect of Lifestyle Modification on Sperm DNA Fragmentation Index [PDF]

Journal of Pharmacy and Bioallied Sciences
Background: Infertility is a growing concern, affecting 8%–12% of reproductive-age couples worldwide. Male infertility accounts for 20%–30% of cases and contributes to 50% of fertility problems.
Neha Nawale, Akash More, Namrata Anjankar, Sanket Mahajan, Radha Bondare   +4 more
doaj   +2 more sources

Sperm DNA Fragmentation: causes, evaluation and management in male infertility. [PDF]

JBRA Assist Reprod
Male infertility is a great matter of concern as out of 15% of infertile couples in the reproductive age, about 40% are contributed by male factors alone.
Andrabi SW, Ara A, Saharan A, Jaffar M, Gugnani N, Esteves SC.   +5 more
europepmc   +2 more sources

From pathophysiology to practice: addressing oxidative stress and sperm DNA fragmentation in Varicocele-affected subfertile men [PDF]

International Brazilian Journal of Urology
Varicocele can reduce male fertility potential through various oxidative stress mechanisms. Excessive production of reactive oxygen species may overwhelm the sperm's defenses against oxidative stress, damaging the sperm chromatin. Sperm DNA fragmentation,
Filipe Tenório Lira Neto, Lucas Ribeiro Campos, Matheus Roque, Sandro C. Esteves   +3 more
doaj   +2 more sources

Sperm DNA Fragmentation: Unraveling Its Imperative Impact on Male Infertility Based on Recent Evidence. [PDF]

Int J Mol Sci
Male factors may be present in up to 50–70% of infertile couples and the prevalence of male infertility accounts for 20–30% of infertility cases. Understanding the mechanisms and causes behind male infertility remains a challenge, but new diagnostic ...
Stavros S, Potiris A, Molopodi E, Mavrogianni D, Zikopoulos A, Louis K, Karampitsakos T, Nazou E, Sioutis D, Christodoulaki C, Skentou C, Gerede A, Zachariou A, Christopoulos P, Panagopoulos P, Domali E, Drakakis P.   +16 more
europepmc   +2 more sources

Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis.

PLoS ONE, 2016
Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo quality, pregnancy rates and increased miscarriage rates. Various methods exist to test sperm DNA fragmentation such as the sperm chromatin structure assay (SCSA), the ...
Maartje Cissen, Madelon van Wely, Irma Scholten, Steven Mansell, Jan Peter de Bruin, Ben Willem Mol, Didi Braat, Sjoerd Repping, Geert Hamer   +8 more
doaj   +2 more sources