DNA fragmentation in spermatozoa and its relationship with impaired spermatogenesis
Sperm cells DNA fragmentation is one of the factors of male sub-/infertility discovered recently. At present, pathophysiological mechanisms that cause DNA fragmentation have not been studied completely.
S. A. Rudneva +7 more
doaj +3 more sources
Progress in Research on Sperm DNA Fragmentation [PDF]
With the increasing incidence of male infertility, routine detection of semen is insufficient to accurately assess male fertility. Infertile men, who have lower odds of conceiving naturally, exhibit high levels of sperm DNA fragmentation (SDF). The mechanisms driving SDF include abnormal spermatogenesis, oxidative stress damage, and abnormal sperm ...
Qiu, Ying +3 more
openaire +2 more sources
Sperm DNA and detection of DNA fragmentations in sperm [PDF]
The questionable effectiveness of routine sperm parameters in determining male factor infertility problems and increasing the success rates of assisted reproductive techniques have led to the investigation of more detailed sperm parameters that could affect the male fertility and reproduction.
openaire +2 more sources
Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis
Background: Opioids have been implicated to induce infertility. Although codeine remains the most used opioid for recreational purpose, no study has documented its effect on sperm quality.
Ayodeji Folorunso Ajayi +1 more
doaj +1 more source
A perspective on sperm DNA fragmentation [PDF]
The paper on sperm DNA fragmentation by Ashok Agarwal et al . summarizes the currently available DNA fragmentation tests and discusses the role of sperm function tests in the intracytoplasmic sperm injection (ICSI) era (1). The authors have summarized the clinical utility of sperm DNA fragmentation test and have provided recommendations based on ...
Pandiyan, Natarajan +2 more
openaire +2 more sources
Fertilization capacity with rainbow trout DNA-damaged sperm and embryo developmental success [PDF]
Mammalian spermatozoa undergo a strong selection process along the female tract to guarantee fertilization by good quality cells, but risks of fertilization with DNA-damaged spermatozoa have been reported.
Ahmadi +31 more
core +1 more source
Background: Male infertility is on the rise globally. It contributes to about 40-50% of all infertility cases. Semen analysis forms the basic investigation for the assessment of male factors of infertility, but it has its pitfalls.
Vidya K +3 more
doaj +1 more source
Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]
Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A. +8 more
core +1 more source
Future direction in sperm DNA fragmentation testing [PDF]
Dr. Rey, in his commentary (1), has provided us with a comprehensive summary of the practice recommendations proposed by Agarwal et al . (2) with additional discussion on the basic physiology of sperm DNA structure.
Cho, Chak-Lam +3 more
openaire +2 more sources
Telomere lengths in human oocytes, cleavage stage embryos and blastocysts [PDF]
Telomeres are repeated sequences that protect the ends of chromosomes and harbour DNA-repair proteins. Telomeres shorten during each cell division in the absence of telomerase.
Achi +42 more
core +2 more sources

