Results 11 to 20 of about 9,914 (214)
Transplantation of spermatogonial stem cells in stallions [PDF]
Journal of Animal Science and TechnologySpermatogonial stem cells originate from gonocytes and undergo self-renewal and differentiation to generate mature spermatozoa via spermatogenesis in the seminiferous tubules of the testis in male mammals. Owing to the unique capacity of these cells, the
Heejun Jung, Minjung Yoon
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Spermatogonial stem cells: Progress and prospects [PDF]
Asian Journal of Andrology, 2015 Twenty years ago, the transplantation of spermatogonial stem cells (SSCs) from a mouse to other recipient mice was shown to be feasible, which clearly demonstrated the functional identity of SSCs.
Mitsuru Komeya, Takehiko Ogawa
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Culture and transplantation of spermatogonial stem cells [PDF]
Stem Cell Research, 2018 The spermatogonial transplantation technique was developed by Dr. Ralph Brinster in 1994. Transplanted spermatogonial stem cells (SSCs) produce germ cell colonies after microinjection into the seminiferous tubules of infertile mice.
Seiji Takashima, Takashi Shinohara
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Defining the spermatogonial stem cell [PDF]
Developmental Biology, 2004 Through the use of donor cells from transgenic rats expressing GFP exclusively in the germline, we have defined culture conditions where male germ cells lose (on STO cells) or maintain (on MSC-1 cells) stem cell activity. A cadre of germ cell transcripts strikingly decrease in relative abundance as a function of testis age or culture time on STO cells,
Kent Hamra, F. +6 more
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Spermatogonial stem cells [PDF]
Current Opinion in Cell Biology, 1998 The mammalian seminiferous epithelium consists of a highly complex yet well-organized cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing transformation to become spermatozoa. To study the factors which control renewal and differentiation of spermatogonial stem cells, animal models are now available which allow for ...
de rooij, D. G., Grootegoed, J. A.
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Isolation and characterization of human spermatogonial stem cells [PDF]
Reproductive Biology and Endocrinology, 2011 Background To isolate and characterization of human spermatogonial stem cells from stem spermatogonium. Methods The disassociation of spermatogonial stem cells (SSCs) were performed using enzymatic digestion of type I collagenase and trypsin.
Liu Shixue +3 more
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ROS amplification drives mouse spermatogonial stem cell self-renewal [PDF]
Life Science Alliance, 2019 Although reactive oxygen species (ROS) are required for spermatogonial stem cell (SSC) self-renewal, the mechanism has remained unknown. We show that SSC self-renewal signals activate MAPK14/MAPK7 pathway to induce nuclear translocation of BCL6B and ...
Hiroko Morimoto +11 more
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The spermatogonial stem cell niche [PDF]
Microscopy Research and Technique, 2009 AbstractSpermatogonial stem cells (SSCs; As spermatogonia) and their direct descendants (Apr and Aal spermatogonia) are preferentially located in those areas of the seminiferous tubules that border on the interstitial tissue. Fewer of these cells are present in tubule areas directly bordering on another tubule.
de Rooij, Dirk G., Dirk G. De Rooij
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Fertility restoration with spermatogonial stem cells [PDF]
Current Opinion in Endocrinology, Diabetes & Obesity, 2017 Purpose of review This review evaluates the state of the art in terms of challenges and strategies used to restore fertility with spermatogonial stem cells retrieved from prepubertal boys affected by cancer. Although these boys do not yet produce spermatozoa, the only option to preserve their fertility is cryopreservation of ...
Francesca, de Michele +2 more
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MAST4 controls cell cycle in spermatogonial stem cells [PDF]
, 2023 Spermatogonial stem cell (SSC) self-renewal is regulated by reciprocal interactions between Sertoli cells and SSCs in the testis. In a previous study, microtubule-associated serine/threonine kinase 4 (MAST4) has been studied in Sertoli cells as a ...
정한성, 이동준
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