Results 41 to 50 of about 9,914 (214)

Culture of mouse spermatogonial stem cells [PDF]

Tissue and Cell, 1998
Spermatogenesis occurs within the seminiferous tubules of mammals by a complex process that is highly organized, extremely efficient and very productive. At the foundation of this process is the spermatogonial stem cell that is capable of both self-renewal and production of progeny cells, which undergo differentiation over a period of weeks to months ...
M, Nagano, M R, Avarbock, E B, Leonida, C J, Brinster, R L, Brinster   +4 more
openaire   +2 more sources

Stem cell protein Piwil2 modulates expression of murine spermatogonial stem cell expressed genes [PDF]

, 2006
The piwi family genes are highly conserved during evolution and play essential roles in stem cell self-renewal, gametogenesis, and RNA interference in diverse organisms ranging from Arabidopsis to human.
Nayernia, K., Engel, Wolfgang, Lee, J. H.   +2 more
core   +1 more source

Propagation of Human Spermatogonial Stem Cells In Vitro [PDF]

, 2009
Context Young boys treated with high-dose chemotherapy are often confronted with infertility once they reach adulthood. Cryopreserving testicular tissue before chemotherapy and autotransplantation of spermatogonial stem cells at a later stage could ...
Korver, Cindy M., van Pelt, Ans M. M., de Rooij, Dirk G., Roepers-Gajadien, Hermien L., van der Veen, Fulco, Mizrak, Sefika C., de La Rosette, Jean J. M. C. H., Koruji, Morteza, de Reijke, Theo M., Sadri-Ardekani, Hooman, van Daalen, Saskia K. M., Hovingh, Suzanne, Repping, Sjoerd   +12 more
core   +1 more source

Mechanistic target of rapamycin kinase (Mtor) is required for spermatogonial proliferation and differentiation in mice

Asian Journal of Andrology, 2020
Spermatogonial development is a vital prerequisite for spermatogenesis and male fertility. However, the exact mechanisms underlying the behavior of spermatogonia, including spermatogonial stem cell (SSC) self-renewal and spermatogonial proliferation and ...
Jun Cao, Zuo-Bao Lin, Ming-Han Tong, Yong-Lian Zhang, Yi-Ping Li, Yu-Chuan Zhou   +5 more
doaj   +1 more source

Roles of Spermatogonial Stem Cells in Spermatogenesis and Fertility Restoration

Frontiers in Endocrinology, 2022
Spermatogonial stem cells (SSCs) are a group of adult stem cells in the testis that serve as the foundation of continuous spermatogenesis and male fertility.
Lei Diao, Paul J. Turek, Constance M. John, Fang Fang, Renee A. Reijo Pera, Renee A. Reijo Pera   +5 more
doaj   +1 more source

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

Advanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu, Yuwei Hu, Xukun Lu, Yuling Cai, Tongtong Li, Ming Gao, Jinlong Ma, Yuan Gao, Shangming Liu, Zi‐Jiang Chen, Jing Meng, Hongbin Liu, Xiaohua Jiang   +12 more
wiley   +1 more source

Genes involved in spermatogonial stem cell self-renewal and differentiation [PDF]

, 2008
Spermatozoa are produced by the process of spermatogenesis. At the base of this process is a pool of spermatogonial stem cells that generate new stem cells as well as committed spermatogonia that will eventually differentiate in spermatozoa.
Genes/proteins responsible for the regulation of proliferation and differentiation of spermatogonial stem cells, van Bragt, M.P.A., Dep Biologie   +2 more
core  

Follicle stimulating hormone increases spermatogonial stem cell colonization during in vitro co - culture [PDF]

Veterinary Research Forum, 2013
The complex process of spermatogenesis is regulated by various factors. Studies onspermatogonial stem cells(SCCs)have provided very important tool to improve herd geneticand different field.
Reza Narenji Sani, Parviz Tajik, Mohammad Hassan Yousefi, Mansoureh Movahedin, Babak Qasemi-Panahi, Shiva Shafiei, Mahmood Ahmadi Hamedani   +6 more
doaj  

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Recent developments in the spermatogonial stem cell field [PDF]

, 2017
This review aims at putting in perspective the many new developments in our understanding of spermatogonial multiplication and stem cell renewal in non-primate mammals..
Sub Developmental Biology, De Rooij, Dirk G., Developmental Biology   +2 more
core   +1 more source