Results 71 to 80 of about 4,947,310 (176)
Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J +19 more
core +1 more source
Successful Transplantation of Frozen-thawed Calf Spermatogonial Stem Cells to the Mouse Testis
Background: Spermatogonial stem cells (SSCs), the only adult stem cells capable of transferring genetic information to the next generation, are important in cell biology. The most important applications of these cells include the treatment of infertility,
Peyman Rahimi-Feyli +4 more
doaj
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu +2 more
wiley +1 more source
Stem cell and stem cell sources in male genital system
Human stem cell research which attracts not only scientists’ but the public’s attention is considered to be able to identify the mechanism of human development, and to change the medical practices.
Gülperi Öktem, Ahmet Barış Altay
doaj +2 more sources
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
Dielectrophoresis: A Review of Applications for Stem Cell Research [PDF]
Dielectrophoresis can discriminate distinct cellular identities in heterogeneous populations, and monitor cell state changes associated with activation and clonal expansion, apoptosis, and necrosis, without the need for biochemical labels.
De Sousa, Paul +7 more
core +1 more source
Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine
Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells).
Maryam Nazm-Bbojnordi +1 more
doaj
Spermatogonial stem cells as a source for regenerative medicine
Several researchers have reported the derivation of multipotent cells from both mouse and human spermatogonial stem cells. These spermatogonia-derived stem cells show similarities with embryonic stem cells both for phenotype and functionality, indicating
Liang Ning +4 more
doaj +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang +4 more
wiley +1 more source

