Results 81 to 90 of about 10,346 (209)

Autologous and homologous transplantation of bovine spermatogonial stem cells [PDF]

, 2003
The aim of this study was to develop a method for spermatogonial stem cell transplantation into the bovine testis. Five-month-old Holstein-Friesian calves were used and half of the calves were hemicastrated to allow autologous transplantation and the ...
Stout, T. A. E., den Ouden, K., Kal, H.B., Oldenbroek, J.K., Woelders, H., Lankveld, D. P. K., van der Ploeg, K., Oldenbroek, J. K., Coret, J., Spoormakers, T.J., de Rooij, D.G., Stout, J., Colenbrander, B., Spoormakers, T. J. P., Kal, H. B., de rooij, D. G., van der Ploeg, K. D., Lankveld, D.P., Stout, T.A.E., Stout, J.E., Izadyar, F.   +20 more
core   +3 more sources

Testicular Architecture Is Critical for Mediation of Retinoic Acid Responsiveness by Undifferentiated Spermatogonial Subtypes in the Mouse

Stem Cell Reports, 2018
Summary: Spermatogenesis requires retinoic acid (RA) induction of the undifferentiated to differentiating transition in transit amplifying (TA) progenitor spermatogonia, whereas continuity of the spermatogenic lineage relies on the RA response being ...
Tessa Lord, Melissa J. Oatley, Jon M. Oatley   +2 more
doaj   +1 more source

A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance

Cell Proliferation, EarlyView.
SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu, Xiya Qiu, Wenying Qu, Yue Ma, Mingyuan Bao, Yuxuan Feng, Xiaochu Wang, Tao Zhou, Bo Zheng, Shunyu Hou, Yu Xia, Qingxia Meng   +11 more
wiley   +1 more source

A single-cell view of spermatogonial stem cells

Current Opinion in Cell Biology, 2020
Spermatogonial stem cells (SSCs) are essential for long-term spermatogenesis and are the subject of considerable clinical interest, as 'SSC therapy' has the potential to cure some forms of male infertility. Recently, we have learned more about SSCs and spermatogenesis in general from a plethora of studies that performed single-cell RNA sequencing ...
Kun Tan, Miles F. Wilkinson
openaire   +3 more sources

Hidden gems in the niche: a new approach to the study of spermatogonial stem cells [PDF]

, 2013
Kanatsu-Shinohara and colleagues continue to reveal the secrets of the rare mammalian spermatogonial stem cells. Their most recent study offers a new approach by applying principles from hematopoietic stem cell research to demonstrate that cells which ...
McLaughlin, Eileen A.; id_orcid, Loveland, Kate L., McLaughlin, Eileen A. (R19932), McLaughlin, Eileen, Loveland, Katherine   +4 more
core   +1 more source

Successful Transplantation of Frozen-thawed Calf Spermatogonial Stem Cells to the Mouse Testis

مجله دانشکده پزشکی اصفهان, 2013
Background: Spermatogonial stem cells (SSCs), the only adult stem cells capable of transferring genetic information to the next generation, are important in cell biology. The most important applications of these cells include the treatment of infertility,
Peyman Rahimi-Feyli, Parviz Tajik, Morteza Koruji, Shiva Shafiei, Maria Zahiri   +4 more
doaj  

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Stem cell and stem cell sources in male genital system

Urology Research and Practice, 2019
Human stem cell research which attracts not only scientists’ but the public’s attention is considered to be able to identify the mechanism of human development, and to change the medical practices.
Gülperi Öktem, Ahmet Barış Altay
doaj   +2 more sources

Mouse and Human Spermatogonial Stem Cells [PDF]

, 2010
Spermatogonial stem cells (SSCs) are in the beginning of a complex process in which theytransmit genetic information from generation to generation. Any failure in this process canresult in infertility.
Azizi, H., Morteza Koruji, Shahverdi, A., Hossein Baharvand, Koruji, M., Abdolhossein Shahverdi, Hossein Azizi, Baharvand, H.   +7 more
core  

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source