Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine
Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells).
Maryam Nazm-Bbojnordi +1 more
doaj
Immunohistochemical analysis of transcription factors in GCNIS associated with pure EC and YST suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche. In these tumors, reprogramming may occur immediately upon invasion of the stroma or within seminiferous tubules but outside the spermatogonial niche (i.e., in intratubular ...
Daisy Maharjan +15 more
wiley +1 more source
Spermatogonial stem cells and in vitro spermatogenesis [PDF]
AbstractSpermatogonial stem cells (SSCs) provide the basis for the life‐long production of enormous numbers of sperm. The nature of these mysterious cells is being clarified. Although they were regarded to be mostly dormant, dividing rarely and remaining static in a niche, their rather dynamic behavior in the seminiferous tubules has been disclosed ...
openaire +2 more sources
The nature and dynamics of spermatogonial stem cells [PDF]
Spermatogonial stem cells (SSCs) are crucial for maintaining spermatogenesis throughout life, and understanding how these cells function has important implications for understanding male infertility. Recently, various populations of cells harbouring stem cell-like properties have been identified in rodent seminiferous tubules, but deciphering how these
openaire +3 more sources
Renal differentiation from adult spermatogonial stem cells [PDF]
There is considerable interest in the use of multi-potent stem cells in kidney tissue regeneration. We studied if spermatogonial stem cells have the ability to undergo kidney differentiation.
Williamson SC +7 more
core
Spermatogonial stem cells as a source for regenerative medicine [PDF]
Several researchers have reported the derivation of multipotent cells from both mouse and human spermatogonial stem cells. These spermatogonia-derived stem cells show similarities with embryonic stem cells both for phenotype and functionality, indicating
Geens, Mieke +4 more
core +1 more source
Culture and Expansion of Primary Undifferentiated Spermatogonial Stem Cells [PDF]
This protocol describes a culture method for supporting the maintenance and expansion of a primary mouse undifferentiated spermatogonial population containing spermatogonial stem cells (SSCs).
Ralph Brinster, Shaun Goodyear
core +1 more source
Etoposide Induces Chromosomal Abnormalities in Spermatocytes and Spermatogonial Stem Cells [PDF]
Etoposide (ET) is a chemotherapeutic agent widely used in the treatment of leukemia, lymphomas and many solid tumors, such as testicular and ovarian cancers, that affect patients in their reproductive years. The purpose of the study was to use sperm FISH
Wyrobek, Andrew J. +3 more
core
Primordial germ cells (spermatogonial stem cells) of bullfrogs express sex hormone-binding globulin and steroid receptors during seasonal spermatogenesis [PDF]
In vertebrate species, testosterone seems to inhibit spermatogonial differentiation and proliferation. However, this androgen can also be converted, via aromatase, into estrogen which stimulates spermatogonial differentiation and mitotic activity. During
Da Luz, Juliana Silva [UNESP] +13 more
core +1 more source
Biology and manipulation technologies of male germline stem cells in mammals
Background Spermatogonial stem cells (SSCs) are the origin of sperm and defined by their functions of “colonization in the testis” and “spermatogenesis”.
Seiji Takashima
doaj +1 more source

