Spermidine reduces ISGylation and enhances ISG15–USP18 interaction
The expression of ubiquitin-like molecule interferon-stimulated gene 15 kDa (ISG15) and its post-translational modification (ISGylation) are significantly activated by interferons or pathogen infections, highlighting their roles in innate immune ...
Haruka Etori +3 more
doaj +1 more source
Significance Statement The shade‐avoidance response allows plants to better access sunlight to compete against surrounding neighbors. In Arabidopsis, PIF7 can be dephosphorylated under shade and accumulates into the nucleus to promote auxin biosynthetic and signaling genes to promote stem elongation.
Xingbo Cai +5 more
wiley +1 more source
Effect of spermidine intake on skeletal muscle regeneration after chemical injury in male mice
Skeletal muscle has a high regenerative ability and maintains homeostasis by rapidly regenerating from frequent damage caused by intense exercise or trauma. In sports, skeletal muscle damage occurs frequently due to intense exercise, so practical methods
Tomohiro Iwata +4 more
doaj +1 more source
Dicyclohexylamine is not an inhibitor of spermidine synthase [PDF]
K W, Batchelor, R A, Smith, N S, Watson
openaire +2 more sources
Spermidine in Alzheimer's Disease: Evidence from Animal Models and Human Studies. [PDF]
Angelucci F +5 more
europepmc +1 more source
Synergistic application of taurine and spermidine enhances wheat tolerance to neodymium stress through redox homeostasis, metabolic adjustment, and nutrient regulation. [PDF]
Iqbal R +9 more
europepmc +1 more source
Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults-A Pilot Study. [PDF]
Alsaleh G +25 more
europepmc +1 more source
Spermidine Targets Ovarian Granulosa Cells via Activating the FHC/SLC7A11 Axis to Regulate Iron Homeostasis and Ameliorate Iron Overload-Induced Ovarian Dysfunction. [PDF]
Niu CY +13 more
europepmc +1 more source

