Results 81 to 90 of about 57,007 (201)

Spermidine promotes Bacillus subtilis biofilm formation by activating expression of the matrix regulator slrR [PDF]

, 2017
Ubiquitous polyamine spermidine is not required for normal planktonic growth of Bacillus subtilis but is essential for robust biofilm formation. However, the structural features of spermidine required for B.
Khomutov, Maxim, Stanley-Wall, Nicola R.; id_orcid, Naidoo, Jacinth, Nicola R. Stanley-Wall, Khomutov, Alexey, Wood, Jennifer L., Sok Ho Kim, Bin Li, Alexey Khomutov, Ana Sofia Ferreira, Li, Bin, Hobley, Laura, Kim, Sok Ho, Anthony J. Michael, Michael, Anthony J., Laura Hobley, Ferreira, Ana Sofia, Maxim Khomutov, Jennifer L. Wood, Jacinth Naidoo   +19 more
core   +1 more source

Presence of PTPN2 SNP rs1893217 enhances the anti-inflammatory effect of spermidine [PDF]

, 2020
BACKGROUND: The single nucleotide polymorphism (SNP) rs1893217 within the gene locus encoding PTPN2 represents a risk factor for inflammatory bowel disease (IBD).
Manz, Salomon, Bäbler, Katharina, Butter, Matthias, Obialo, Nicole, Niechcial, Anna, Spalinger, Marianne R, van der Lely, Lisa, Lang, Silvia, Gottier, Claudia, McCole, Declan F, Scharl, Michael, van der Lely L, Butter M, Gottier C, Obialo N, Niechcial A, Bäbler K, McCole DF, Spalinger MR, Lang S, Manz S, Scharl M   +21 more
core   +1 more source

Potential of Seaweed to Improve the Quality and Shelf Life of Fish and Fishery Products

Food Safety and Health, EarlyView.
Growing global demand for safe fish preservation has increased interest in natural alternatives. Seaweed‐derived bioactive compounds possess antioxidant and antimicrobial properties that enhance fish quality, safety, and shelf life. These sustainable preservatives may reduce spoilage and synthetic preservative use, though further research ...
Ashika Banu Rodela, Md. Golam Rasul, Ilias Ebne Kabir, Jahid Hasan, Chunhong Yuan, Bhaskar Chandra Majumdar   +5 more
wiley   +1 more source

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

iMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He, Qiwen Wang, Luyi Chen, Yadong Qi, Dingjiacheng Jia, Jilei Xu, Qingyi Wang, Yao Jiang, Jian Zhou, Yong Sun, Ruochen Yan, Lan Wang, Tongyao Hou, Zheng Kuang, Min Jin, Liangjing Wang, Shujie Chen   +16 more
wiley   +1 more source

Spermidine Enhances Mitochondrial Bioenergetics in Young and Aged Human-Induced Pluripotent Stem Cell-Derived Neurons

Antioxidants
The accumulation of damaged mitochondria has long been considered a hallmark of the aging process. Among various factors, age-related mitochondrial alterations comprise bioenergetic impairments and disturbances in reactive oxygen species (ROS) control ...
Leonora Szabo, Imane Lejri, Amandine Grimm, Anne Eckert   +3 more
doaj   +1 more source

Modeling of spermidine binding to hOCT2.

, 2014
(A) Amino acid residues involved in transport activity of the three amines (red) and of putrescine and spermidine (blue) are shown on α-helices 1 to 12, whose relative positions were constructed based on the structure model of hOCT2 [31]. (B) View of the
Ryotaro Saiki (597499), Masataka Imamura (597496), Satoshi Fudo (597497), Kazuei Igarashi (597503), Toshihiko Toida (597501), Keiko Kashiwagi (597502), Takeshi Uemura (597498), Tyuji Hoshino (597500), Kyohei Higashi (597495)   +8 more
core   +1 more source

Spermidine-induced macrophage reprogramming for liver fibrosis treatment

, 2023
Liver fibrosis can be regarded as an aberrant wound-healing process in response to chronic hepatic injury, which is characterized by extracellular matrix deposition leading to the generation of the fibrous scar and subsequent hepatic dysfunction ...
LIU, RUI
core   +1 more source

Beyond a dual role: how Purpureocillium lilacinum reprograms citrus metabolism for integrated biocontrol and growth promotion

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Plants harbor complex microbial communities that are fundamental to their health and productivity. Among them, endophytic fungi such as Purpureocillium lilacinum establish mutualistic associations, offering dual benefits as plant growth promoters and biocontrol agents.
Sana Bouzembila, Kamel Charaabi, Haytham Hamden, Salma Fadhel, Nesrine Tanfouri, Meriem Msaad Guerfali   +5 more
wiley   +1 more source

Spermidine enhances steroidogenesis by elevating eIF5Ahyp level in hierarchical follicular granulosa cells of the goose

Poultry Science
Imbalanced steroid hormone levels in female poultry can impair follicular development, thereby adversely affecting reproductive performance. Spermidine is reported to be involved in regulation of female reproduction and can provide aminobutyl as the only
Dongmei Jiang, Chengweng Ji, Qian Sun, Yuxin Qi, Shuo Li, Xiaoguang An, Weikang Ling, Xin Wang, Chunyang Niu, Bo Kang   +9 more
doaj   +1 more source

The Oncologic Ambivalence of Longevity Interventions in Photoaged Skin

JEADV Clinical Practice, EarlyView.
This graphical abstract presents a stage‐dependent framework for longevity interventions in photoaged skin. UV exposure drives progression from photodamage to field cancerization and skin cancer. Systemic interventions may modulate stress‐response pathways throughout the body, whereas energy‐based procedures generate spatially confined responses ...
Erik Senger, Lea Kurzen, Hjalmar Kurzen
wiley   +1 more source