Results 131 to 140 of about 77,896 (237)

A role for antizyme inhibitor 2 in the biosynthesis and content of serotonin and histamine in mouse mast cells [PDF]

open access: yes, 2015
Polyamines (putrescine, spermidine and spermine; PAs) are essential for the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine decarboxylase and PA uptake.
Acosta-Andrade, Carlos   +5 more
core  

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang   +8 more
wiley   +1 more source

A molecular probe for Basidiomycota: the spermidine synthase-saccharopine dehydrogenase chimeric gene [PDF]

open access: bronze, 2010
Claudia Geraldine León-Ramírez   +5 more
openalex   +1 more source

Synthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li   +4 more
wiley   +1 more source

Root protein interatomic network obtained from citrus seedlings subjected to water deficit : S08O03 [PDF]

open access: yes, 2012
Citrus Brazilian industry may be strongly affected by drought. Characterize rootstock behavior under different environmental conditions is crucial, since rootstocks may confer better adaption to environmental stresses.
Bonatto, Diego   +7 more
core  

The association of dietary spermidine with all-cause mortality and CVD mortality: The U.S. National Health and Nutrition Examination Survey, 2003 to 2014

open access: gold, 2022
Huanyu Wu   +11 more
openalex   +1 more source

Transcriptional Analysis and Genome‐Wide Identification of HA, FRO, and IRT Gene Families Reveal Key Regulators in Pear Seedlings to Short‐Term Iron Deficiency Stress

open access: yesFood and Energy Security, Volume 15, Issue 1, January/February 2026.
ABSTRACT Iron (Fe) is an essential micronutrient for plant photosynthesis and human health. Pear represents a widely consumed fruit for human Fe intake, yet its yield and quality are frequently challenged by Fe deficiency (FD) stress. Despite the prevalence of FD stress in agricultural production under generally alkaline and calcareous conditions, pear
Guoling Guo   +11 more
wiley   +1 more source

Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh   +4 more
wiley   +1 more source

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