Results 131 to 140 of about 77,896 (237)
A role for antizyme inhibitor 2 in the biosynthesis and content of serotonin and histamine in mouse mast cells [PDF]
Polyamines (putrescine, spermidine and spermine; PAs) are essential for the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine decarboxylase and PA uptake.
Acosta-Andrade, Carlos +5 more
core
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang +8 more
wiley +1 more source
A molecular probe for Basidiomycota: the spermidine synthase-saccharopine dehydrogenase chimeric gene [PDF]
Claudia Geraldine León-Ramírez +5 more
openalex +1 more source
Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li +4 more
wiley +1 more source
Root protein interatomic network obtained from citrus seedlings subjected to water deficit : S08O03 [PDF]
Citrus Brazilian industry may be strongly affected by drought. Characterize rootstock behavior under different environmental conditions is crucial, since rootstocks may confer better adaption to environmental stresses.
Bonatto, Diego +7 more
core
Spermidine metabolism in parasitic protozoa - a comparison to the situation in prokaryotes, viruses, plants and fungi [PDF]
Annette Kaiser +4 more
openalex +1 more source
ABSTRACT Iron (Fe) is an essential micronutrient for plant photosynthesis and human health. Pear represents a widely consumed fruit for human Fe intake, yet its yield and quality are frequently challenged by Fe deficiency (FD) stress. Despite the prevalence of FD stress in agricultural production under generally alkaline and calcareous conditions, pear
Guoling Guo +11 more
wiley +1 more source
Effects of Spermidine on Gut Microbiota Modulation in Experimental Abdominal Aortic Aneurysm Mice [PDF]
Shuai Liu +5 more
openalex +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source

