Results 131 to 140 of about 34,064 (250)
Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang +7 more
wiley +1 more source
This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu +5 more
wiley +1 more source
Salinity is one of the most challenging environmental factors limiting plant development and yield by interfering with key physiological and metabolic activities.
Md Mukhtar Hossain +3 more
doaj +1 more source
Spermine Enhances the Peroxidase Activities of Multimeric Antiparallel G-quadruplex DNAzymes
G-quadruplex (G4) DNAzymes with peroxidase activities hold potential for applications in biosensing. While these nanozymes are easy to assemble, they are not as efficient as natural peroxidase enzymes.
Raphael I. Adeoye +9 more
doaj +1 more source
The polyamine spermine regulates osteogenic differentiation in adipose stem cells
For bone tissue engineering, it is important that mesenchymal stem cells (MSCs) differentiate into osteoblasts. To develop a method for differentiation of adipose tissue-derived mesenchymal stem cells (AT-MSCs) along the osteogenic lineage, we studied ...
Zandieh-Doulabi, B. +6 more
core +1 more source
Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
Proposed microbiome‐related pathways and translational landscape in glioblastoma. Gut dysbiosis may alter microbial metabolites, inflammatory mediators, barrier integrity, immune signaling, and vagal communication, thereby influencing the GBM neuroimmune microenvironment.
Tareq Nayef AlRamadneh +8 more
wiley +1 more source
Spermine Significantly Increases the Transfection Efficiency of Cationic Polymeric Gene Vectors
Background/Objectives: Non-viral vectors have gained recognition for their ability to enhance the safety of gene delivery processes. Among these, polyethyleneimine (PEI) stands out as the most widely utilized cationic polymer due to its accessibility ...
Yue Lv +3 more
doaj +1 more source
Effect of SFN and spermine on glutathione levels in Jurkat cells.
Effect of SFN, spermine and SFN plus spermine on glutathione level determined by microplate fluorescence reader. Cells were treated for 3 h (A) or 24 h (B) with SFN (10 µM), spermine (0.5 mM) or SFN (10 µM)+spermine (0.5 mM).
Carmela Fimognari (325456) +6 more
core +1 more source
Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma +9 more
wiley +1 more source

