Results 161 to 170 of about 176,600 (181)
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Biochemical and Biophysical Research Communications, 1994
The observation that spermine inhibits the endotoxin (lipopolysaccharide; LPS) induced production of nitric oxide (NO) in macrophages has been ascribed to the conversion of SP to active metabolites by the action of enzymes, such as diamine oxidases, found, for example, in bovine sera.
G J, Southan, C, Szabó, C, Thiemermann
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The observation that spermine inhibits the endotoxin (lipopolysaccharide; LPS) induced production of nitric oxide (NO) in macrophages has been ascribed to the conversion of SP to active metabolites by the action of enzymes, such as diamine oxidases, found, for example, in bovine sera.
G J, Southan, C, Szabó, C, Thiemermann
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American Journal of Medical Genetics Part A, 2013
ABSTRACTSnyder–Robinson syndrome is a rare form of X‐linked intellectual disability caused by mutations in the spermine synthase (SMS) gene, and characterized by intellectual disability, thin habitus with diminished muscle mass, osteoporosis, kyphoscoliosis, facial dysmorphism (asymmetry, full lower lip), long great toes, and nasal or dysarthric speech.
A. Peron +8 more
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ABSTRACTSnyder–Robinson syndrome is a rare form of X‐linked intellectual disability caused by mutations in the spermine synthase (SMS) gene, and characterized by intellectual disability, thin habitus with diminished muscle mass, osteoporosis, kyphoscoliosis, facial dysmorphism (asymmetry, full lower lip), long great toes, and nasal or dysarthric speech.
A. Peron +8 more
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Cell-type specific roles of spermine synthase on autophagy in Tauopathy
Alzheimer's disease (AD) and related tauopathies are characterized by pathological Tau protein accumulation and impaired autophagy. Polyamine metabolism has emerged as a key pathway at the intersection of autophagy and Tauopathy; however, its underlying mechanisms remain poorly understood, limiting its therapeutic potential.openaire +1 more source