Using animal models to decipher the role of polyamines in the pancreas and β Cell. [PDF]
Puente AA +4 more
europepmc +1 more source
Polyamines as Gatekeepers of Virus Replication and Central Nervous System Homeostasis. [PDF]
Stacey SP, Mounce BC.
europepmc +1 more source
Decoding polyamine-ethylene dynamics: synergies at synthesis and signalling levels during osmotic stress and ripening. [PDF]
Gupta S +6 more
europepmc +1 more source
SRM-Mediated Spermidine Synthesis Links Lipid Overload With AMPK Pathway to Regulate Hepatic Insulin Signaling and Gluconeogenesis. [PDF]
Zhao Z +12 more
europepmc +1 more source
Case Report: A new patient expanding the clinical spectrum of <i>DOHH</i>-associated syndrome with increased nuchal translucency, cardiomyopathy, hypoparathyroidism and mild intellectual disability. [PDF]
Daire E +6 more
europepmc +1 more source
Spermine oxidase promotes oxidative stress during islet inflammation. [PDF]
Checkcinco C +7 more
europepmc +1 more source
The role of spermidine in plants and humans: a pathway from climate change adaptation to health benefits. [PDF]
Blagojević BD +7 more
europepmc +1 more source
Polyamines are ubiquitous positively charged metabolites that play an important role in wide fundamental cellular processes; because of their importance, the homeostasis of these amines is tightly regulated. Spermine synthase catalyzes the formation of polyamine spermine, which is necessary for growth and development in higher eukaryotes.
Alejandro Ferrando +2 more
exaly +5 more sources
Long-range effect of a single mutation in spermine synthase
Spermine synthase (SpmSyn) is an enzyme critical for maintaining the balance of spermine/spermidine in the cell. The amino acid sequence of SpmSyn is highly conserved among the species. Most of the mutations found in the human population are shown to be causing Snyder–Robinson syndrome, a severe mental disorder, while not so many are neutral.
Yunhui Peng, Ekaterina Michonova
openaire +2 more sources

