Results 141 to 150 of about 176,600 (181)

Using animal models to decipher the role of polyamines in the pancreas and β Cell. [PDF]

open access: yesAmino Acids
Puente AA   +4 more
europepmc   +1 more source

SRM-Mediated Spermidine Synthesis Links Lipid Overload With AMPK Pathway to Regulate Hepatic Insulin Signaling and Gluconeogenesis. [PDF]

open access: yesFASEB J
Zhao Z   +12 more
europepmc   +1 more source

Spermine oxidase promotes oxidative stress during islet inflammation. [PDF]

open access: yesJ Biol Chem
Checkcinco C   +7 more
europepmc   +1 more source

The role of spermidine in plants and humans: a pathway from climate change adaptation to health benefits. [PDF]

open access: yesNPJ Sci Food
Blagojević BD   +7 more
europepmc   +1 more source

Characterization of maize spermine synthase 1 (ZmSPMS1): Evidence for dimerization and intracellular location

open access: yesPlant Physiology and Biochemistry, 2015
Polyamines are ubiquitous positively charged metabolites that play an important role in wide fundamental cellular processes; because of their importance, the homeostasis of these amines is tightly regulated. Spermine synthase catalyzes the formation of polyamine spermine, which is necessary for growth and development in higher eukaryotes.
Alejandro Ferrando   +2 more
exaly   +5 more sources

Long-range effect of a single mutation in spermine synthase

open access: yesJournal of Theoretical and Computational Chemistry, 2018
Spermine synthase (SpmSyn) is an enzyme critical for maintaining the balance of spermine/spermidine in the cell. The amino acid sequence of SpmSyn is highly conserved among the species. Most of the mutations found in the human population are shown to be causing Snyder–Robinson syndrome, a severe mental disorder, while not so many are neutral.
Yunhui Peng, Ekaterina Michonova
openaire   +2 more sources

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