Results 121 to 130 of about 321,693 (208)
Brazilian Journal of Medical and Biological Research, 2000 The objective of the present study was to explore the regulatory mechanisms of free radicals during streptozotocin (STZ)-induced pancreatic damage, which may involve nitric oxide (NO) production as a modulator of cellular oxidative stress.
E. González +9 more
doaj +1 more source
Dermatology Research and Practice, 2017 Ischaemic insult in the skin flaps is a major problem in reconstructive surgery particularly in patients with diabetes mellitus. Here, we sought to investigate the effectiveness of ischaemic preconditioning (IP) on diabetic skin flaps in rat animal model.
Christian Ottomann +3 more
doaj +1 more source
Biologia Plantarum, 2016 Polyamines play important roles in plant responses to various environmental stresses. In this study, changes in free polyamine content and transcription of genes participating in polyamine metabolism were investigated in sweet orange (Citrus sinensis ...
X. Z. Fu +6 more
doaj +1 more source
Vaginal biogenic amines: biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis? [PDF]
, 2015 Bacterial vaginosis (BV) is the most common vaginal disorder among reproductive age women. One clinical indicator of BV is a "fishy" odor. This odor has been associated with increases in several biogenic amines (BAs) that may serve as important
Carl J. Yeoman +5 more
core +1 more source
Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. [PDF]
, 2019 Genome wide association studies (GWAS) in obesity have identified a large number of noncoding loci located near genes expressed in the central nervous system.
Ahituv, Nadav +6 more
core +1 more source
Purification of spermine synthase from bovine brain by spermine—Sepharose affinity chromatography [PDF]
FEBS Letters, 1978 Pajula, R-L., Raina, A., Kekoni, J.
openaire +2 more sources
Polyamine Metabolism in Brain Health and Disease
Neuropharmacology and TherapyPolyamines, primarily spermidine and spermine, are small polycationic molecules essential for cell growth, signaling, and survival. Through electrostatic interactions with nucleic acids, lipids, and proteins, they regulate gene expression, organelle ...
Xianzun Tao +2 more
doaj +1 more source
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice. [PDF]
, 2020 Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of functionally versatile proteins that play critical roles in the biogenesis, cellular localization and transport of RNA.
Feng, An-Chieh +14 more
core
Association of polyaminergic loci with anxiety, mood disorders, and attempted suicide.
PLoS ONE, 2010 BackgroundThe polyamine system has been implicated in a number of psychiatric conditions, which display both alterations in polyamine levels and altered expression of genes related to polyamine metabolism.
Laura M Fiori +7 more
doaj +1 more source
Crystal Structure of Human Spermine Synthase [PDF]
Journal of Biological Chemistry, 2008 Hong Wu +8 more
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