Results 101 to 110 of about 176,600 (181)

The Trypanosoma brucei sphingolipid synthase, an essential enzyme and a drug target [PDF]

, 2009
Sphingolipids are important structural components of eukaryotic membranes, in addition they and their precursors are involved in signal transduction processes.
Pan, Ssu-Ying
core  

Cloning and characterization of novel methylsalicylic acid synthase gene involved in the biosynthesis of isoasperlactone and asperlactone in Aspergillus westerdijkiae [PDF]

, 2009
Aspergillus westerdijkiae is the main producer of several biologically active polyketide metabolites including isoasperlactone and asperlactone. A 5298 bp polyketide synthase gene ‘‘aomsas” has been cloned in Aspergillus westerdijkiae by using gene ...
Atoui, Ali, Dobson, Alan D. W., Mathieu, Florence, Puel, Olivier, Dao, Huy Phong, Liboz, Thierry, O’Callaghan, John, O'Callaghan, John, Bacha, Nafees, Dobson, Alan D.W., Lebrihi, Ahmed   +10 more
core   +1 more source

Stimulation in vitro of vitamin B₁₂-dependent methionine synthase by polyamines [PDF]

, 1996
Vitamin B12-dependent methionine synthase is an important enzyme for sulphur amino acid, folate polyamine metabolism, S-adenosylmethionine metabolism and also in the methylation pathway of DNA, RNA, proteins and lipids.
Nicolaou, Anna; id_orcid, Gibbons, WA, Ast, T., Kenyon, SH   +3 more
core   +1 more source

A new type of Na+-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif [PDF]

, 2013
: The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na+. Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F1Fo-ATP synthase with a novel Na ...
Leone, V, Yildiz, Ö, Meier, T, Iglesias-Cans, M, Cook, G., Sarah Schulz (426341), Meier, Thomas, Sarah Schulz, Matthies, D., Meier, T. ; https://orcid.org/, Schulz, Sarah, Özkan Yildiz (244574), M. Cook, Gregory, Doreen Matthies (426343), Thomas Meier, José D. Faraldo-Gómez (426344), Faraldo-Gómez, J., José D Faraldo-Gómez, Yildiz, Ö. ; https://orcid.org/, Iglesias-Cans, Marina, Gregory M. Cook (255231), Krah, A, Alexander Krah, https://orcid.org/, Vanessa Leone, Cook, Gregory M., Yildiz, Özkan, Meier, Thomas Kurt, Alexander Krah (217992), Cook, GM, Iglesias-Cans, M., Schulz, S, Doreen Matthies, Schulz, S., Leone, Vanessa, Matthies, D, Leone, V., Marina Iglesias-Cans, Marina Iglesias-Cans (426342), Thomas Meier (244580), Gregory M Cook, Krah, Alexander, Matthies, Doreen, Faraldo-Gómez, José D., Faraldo-Gómez, JD, Vanessa Leone (266195), Ozkan Yildiz, Krah, A.   +47 more
core   +2 more sources

Pancreatic nitric oxide and oxygen free radicals in the early stages of streptozotocin-induced diabetes mellitus in the rat

Brazilian Journal of Medical and Biological Research, 2000
The objective of the present study was to explore the regulatory mechanisms of free radicals during streptozotocin (STZ)-induced pancreatic damage, which may involve nitric oxide (NO) production as a modulator of cellular oxidative stress.
E. González, J. Roselló-Catafau, A. Jawerbaum, D. Sinner, C. Pustovrh, J. Vela, V. White, C. Xaus, C. Peralta, M. Gimeno   +9 more
doaj   +1 more source

The essential roles of cytidine diphosphate-diacylglycerol synthase in bloodstream form Trypanosoma brucei [PDF]

, 2014
Funded by Wellcome Trust: Senior Research Fellowship, Grant Number: 067441 and Wellcome Trust, Grant Numbers: 082596, 093228.Lipid metabolism in Trypanosoma brucei, the causative agent of African sleeping sickness, differs from its human host in several ...
Lilley, Alison C., Smith, Terry K., Smith, Terry K, Young, Simon, Stark, Michael J. R., Lilley, Alison Catherine, Major, Louise Laura, Major, Louise   +7 more
core   +1 more source

Integrated analysis of the metabolome and transcriptome reveals the effect of the polyamine biosynthesis pathway on the cold resistance regulation mechanism in Solanum habrochaites

Horticultural Plant Journal
Constant exposure of tomato fruit to low temperatures (LT) often results in insufficient energy to sustain growth and development. Polyamines (PAs) are essential substances for cell division, development and stress responses in plants.
Meiliang Wang, Tianyang Liu, Tianyu Zhang, Ruihua Gao, Tingting Gu, Yao Zhang, Xiuling Chen, Jiayin Liu, Aoxue Wang, Youwen Qiu   +9 more
doaj   +1 more source

Spermine synthase (SMS) serves as a prognostic biomarker in head and neck squamous cell carcinoma: a bioinformatics analysis. [PDF]

Ann Transl Med, 2022
Pan X, Xue L, Sun Y.
europepmc   +1 more source

Ischaemic Preconditioning Suppresses Necrosis of Adipocutaneous Flaps in a Diabetic Rat Model Regardless of the Manner of Preischaemia Induction

Dermatology Research and Practice, 2017
Ischaemic insult in the skin flaps is a major problem in reconstructive surgery particularly in patients with diabetes mellitus. Here, we sought to investigate the effectiveness of ischaemic preconditioning (IP) on diabetic skin flaps in rat animal model.
Christian Ottomann, Markus Küntscher, Bernd Hartmann, Vlado Antonic   +3 more
doaj   +1 more source

Changes in free polyamines and expression of polyamine metabolic genes under drought and high-temperature in Citrus sinensis

Biologia Plantarum, 2016
Polyamines play important roles in plant responses to various environmental stresses. In this study, changes in free polyamine content and transcription of genes participating in polyamine metabolism were investigated in sweet orange (Citrus sinensis ...
X. Z. Fu, Y. Huang, F. Xing, C. P. Chun, L. L. Ling, L. Cao, L. Z. Peng   +6 more
doaj   +1 more source