Results 111 to 120 of about 321,693 (208)
Efferocytosis: Signaling Pathways and New Therapeutic Strategies for Diseases
MedComm, Volume 7, Issue 5, May 2026.1. Efferocytosis coordinates molecular signaling and metabolic reprogramming to resolve inflammation. 2. Efferocytosis dysfunction underlies four conserved pathological hallmarks across diseases. 3. Therapeutic strategies targeting efferocytosis should be context‐dependent: enhance or inhibit based on disease type. ABSTRACT Efferocytosis—the phagocytic
Lei Wang +6 more
wiley +1 more source
Nano‐Enabled Toxicity of Pharmaceutical Excipients
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 3, May/June 2026.Excipients regarded as safe in bulk form may become toxic once incorporated into nanocarriers. This review raises awareness of nano‐enabled toxicity and highlights analytical tools and safer alternative excipients to support risk‐mitigated nanomedicine development.
Ilaria Polidori +2 more
wiley +1 more source
Frontiers in OncologyIntroductionTumor transformation and progression are accompanied by multiple carcinogenic pathways that dysregulate polyamine demand and metabolism. The importance of polyamines has demonstrated that their metabolism is a potential therapeutic strategy ...
Yujia Zhao +9 more
doaj +1 more source
Interplay of RNA m6A/m1A/m5C/m7G/ψ Regulators Predicting the Prognosis of Pancreatic Cancer
FASEB BioAdvances, Volume 8, Issue 5, May 2026.In this study, we comprehensively analyze the 64 RNA modification regulators, including 24 m6A regulators, 13 m1A regulators, 12 m5C regulators, 9 m7G regulators, and 12 pseudouridine regulators in pancreatic cancer in TCGA, GTEx, and HPA databases. We investigate their RNA and protein expression, their association with patients' clinical significance,
Shiyin Chen +4 more
wiley +1 more source
The key enzyme for mannosylglyceramide synthesis in Rhodothermus marinus [PDF]
, 2010 Mestrado em Biologia AplicadaNa presença de elevadas concentrações de sal no meio de cultura a bactéria halotermofílica Rhodothermus marinus acumula no interior das células compostos orgânicos de baixo peso molecular designados solutos compatíveis ...
Ferreira, Ana Catarina Morouço
core
HIF- and Non-HIF-Regulated Hypoxic Responses Require the Estrogen-Related Receptor in Drosophila melanogaster [PDF]
, 2013 Low-oxygen tolerance is supported by an adaptive response that includes a coordinate shift in metabolism and the activation of a transcriptional program that is driven by the hypoxia-inducible factor (HIF) pathway.
Baker, Keith D. +5 more
core +4 more sources
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
FEBS Open Bio, Volume 16, Issue 4, Page 766-777, April 2026.Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
Analysis of the Developmental Regulation of the Cyanogenic Compounds in Seedlings of Two Lines of \u3cem\u3eLinum usitatissimum\u3c/em\u3e L. [PDF]
, 2003 The developmental profiles and tissue distribution of the four cyanogenic compounds in seedlings of two developmentally contrasting inbred lines of flax (Linum usitatissimum L.) were examined using HPLC.
Fieldes, Mary Ann, Krech, M.J.
core +1 more source
, 2016 Transgenic plants of Nicotiana tabacum L. homozygous for an RNAi construct designed to silence ornithine decarboxylase (ODC) had significantly lower concentrations of nicotine and nornicotine, but significantly higher concentrations of anatabine ...
Blomstedt, Cecilia K. +5 more
core +1 more source
Induction of hyperammonia in irradiated hepatoma cells: a recapitulation and possible explanation of the phenomenon [PDF]
, 2004 Item does not contain ...
J van Rijn +12 more
core +1 more source