Results 61 to 70 of about 321,693 (208)
Effect of spermine synthase on the sensitivity of cells to anti-tumour agents [PDF]
Biochemical Journal, 2003 The role of spermine in the sensitivity of cells to various established and experimental anti-tumour agents was examined, using paired cell lines that possess or lack spermine synthase. All spermine-synthase-deficient cells had no detectable spermine, and elevated spermidine, content. Spermine content did not alter the cell growth rate.
Yoshihiko, Ikeguchi +3 more
openaire +2 more sources
Response to Cadmium Toxicity: Orchestration of Polyamines and microRNAs in Maize Plant
Plants, 2023 Cadmium (Cd) is a heavy metal that is widely contaminating the environment due to its uses in industries as corrosive reagents, paints, batteries, etc.
Seyedeh Batool Hassani +12 more
doaj +1 more source
Putative spermine synthases from Thalassiosira pseudonana and Arabidopsis thaliana synthesize thermospermine rather than spermine [PDF]
FEBS Letters, 2007 Polyamines are involved in many fundamental cellular processes. Common polyamines are putrescine, spermidine and spermine. Spermine is synthesized by transfer of an aminopropyl residue derived from decarboxylated S‐adenosylmethionine to spermidine. Thermospermine is an isomer of spermine and assumed to be synthesized by an analogous mechanism. However,
Knott, Jürgen M. +2 more
openaire +2 more sources
Animals, 2021 κ-Carrageenan is a plant polysaccharide derived from red seaweeds reported to possess potential medicinal and antioxidants activities. The present study aimed to identify the cryoprotective effects of κ-carrageenan on the quality of frozen-thawed canine ...
Eunji Kim +4 more
doaj +1 more source
Kinetic properties of spermine synthase from bovine brain [PDF]
Biochemical Journal, 1983 A kinetic analysis including initial-velocity and product-inhibition studies were performed with spermine synthase purified from bovine brain. The enzyme activity was assayed in the presence of 5′-methylthioadenosine phosphorylase as an auxiliary enzyme to prevent the accumulation of the inhibitory product, 5′-methylthioadenosine, and thus to obtain ...
openaire +2 more sources
Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages [PDF]
, 2014 Macrophages play a major role in the immune system, both as antimicrobial effector cells and as immunoregulatory cells, which induce, suppress or modulate adaptive immune responses.
Abebe +120 more
core +2 more sources
Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish
Biology Open, 2016 Polyamines are small poly-cations essential for all cellular life. The main polyamines present in metazoans are putrescine, spermidine and spermine.
Hans Georg Frohnhöfer +10 more
doaj +1 more source
Molecules, 2019 Polyamines have been reported to be involved in grain filling and they might contribute to the construction of heat resistance of some cereals. In this study, the hybrid rice ‘YLY 689’ was used to explore the possible effects of exogenous ...
Yuying Fu +8 more
doaj +1 more source
Frontiers in Plant Science, 2021 Soil arbuscular mycorrhizal fungi (AMF) enhance the tolerance of plants against soil moisture deficit stress (SMDS), but the underlying mechanisms are still not fully understood. Polyamines (PAs) as low-molecular-weight, aliphatic polycations have strong
Ying-Ning Zou +5 more
doaj +1 more source
Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels [PDF]
, 2010 BACKGROUND: Plasmodium falciparum, the causative agent of severe human malaria, has evolved to become resistant to previously successful antimalarial chemotherapies, most notably chloroquine and the antifolates.
John VW Becker +8 more
core +1 more source