Results 41 to 50 of about 176,600 (181)
Hierarchical Assembly Pathways of Spermine Induced Tubulin Conical-Spiral Architectures [PDF]
, 2020 Tubulin, an essential cytoskeletal protein, assembles into various morphologies by interacting with cellular factors. Spermine, an endogenous polyamine, promotes and stabilizes tubulin assemblies.
Raviv, Dharan +5 more
core +1 more source
, 2023 The manuscript dataset entitled "Potentilla sericea stress-responsive spermine synthase PsSPMS enhances cadmium tolerance in Arabidopsis thaliana" includes data and calculations for fluorescence quantification.THIS DATASET IS ARCHIVED AT DANS ...
Gao, B (via Mendeley Data)
core +1 more source
Polyamine Homeostasis in Snyder-Robinson Syndrome
Medical Sciences, 2018 Loss-of-function mutations of the spermine synthase gene (SMS) result in Snyder-Robinson Syndrome (SRS), a recessive X-linked syndrome characterized by intellectual disability, osteoporosis, hypotonia, speech abnormalities, kyphoscoliosis, and seizures ...
Tracy Murray-Stewart +4 more
doaj +1 more source
Biomolecules, 2023 The triamine spermidine is a key metabolite of the polyamine pathway. It plays a crucial role in many infectious diseases caused by viral or parasitic infections.
Annette Kaiser
doaj +1 more source
, 2021 Snyder Robinson Syndrome (SRS) is a rare disease associated with a defective spermine synthase gene and low intracellular spermine levels. In this study, a spermine replacement therapy was developed using a spermine prodrug that enters cells via the ...
Mukund P. Tantak (11604682) +4 more
core +3 more sources
Effect of spermine synthase on the sensitivity of cells to anti-tumour agents [PDF]
Biochemical Journal, 2003 The role of spermine in the sensitivity of cells to various established and experimental anti-tumour agents was examined, using paired cell lines that possess or lack spermine synthase. All spermine-synthase-deficient cells had no detectable spermine, and elevated spermidine, content. Spermine content did not alter the cell growth rate.
Yoshihiko, Ikeguchi +3 more
openaire +2 more sources
Perturbation of spermine synthase Gene Expression and Transcript Profiling Provide New Insights on the Role of the Tetraamine Spermine in Arabidopsis Defense against Pseudomonas viridiflava1[C][W] [PDF]
, 2011 The role of the tetraamine spermine in plant defense against pathogens was investigated by using the Arabidopsis (Arabidopsis thaliana)-Pseudomonas viridiflava pathosystem.
María Elisa Gonzalez +23 more
core +1 more source
Frontiers in Immunology, 2022 Disorders of polyamine metabolism may contribute to the development of hepatocellular carcinoma (HCC), but the precise mechanism remains unknown.
Lin Xiang +3 more
doaj +1 more source
Kinetic properties of spermine synthase from bovine brain [PDF]
Biochemical Journal, 1983 A kinetic analysis including initial-velocity and product-inhibition studies were performed with spermine synthase purified from bovine brain. The enzyme activity was assayed in the presence of 5′-methylthioadenosine phosphorylase as an auxiliary enzyme to prevent the accumulation of the inhibitory product, 5′-methylthioadenosine, and thus to obtain ...
openaire +2 more sources
Spermine-Based Poly(β-amino ester)s for siRNA Delivery against Mutated KRAS in Lung Cancer
, 2023 Polyethylenimine (PEI) is a highly efficient cationic polymer for nucleic acid delivery, and although it is commonly used in preclinical studies, its clinical application is limited because of concerns regarding its cytotoxicity. Poly(β-amino ester)s are
Lorenz Isert (16826940) +9 more
core +1 more source