Results 41 to 50 of about 787 (175)

First experiences in real clinical practice treating a patient with generalised pustular psoriasis with Spesolimab

JEADV Clinical Practice, 2023
Generalised pustular psoriasis is a rare, unpredictable, and sometimes severe subtype of psoriasis whose treatment is hampered by a lack of consensus and standardised therapeutic guidelines.
Aurora Fernández‐Galván, Esteban Daudén, Beatriz Butron‐Bris, Mireia Seguí‐Olmedilla, Ana Miguélez, Javier Fraga, Pedro Rodríguez Jiménez, Mar Llamas‐Velasco   +7 more
doaj   +1 more source

Spesolimab Rapidly Resolved Capillary Leak Syndrome Associated with Generalized Pustular Psoriasis

Acta Dermato-Venereologica
Yoshiki Okada, Masahiro Kamata, Kotaro Hayashi, Kazumitsu Sugiura, Yayoi Tada   +4 more
doaj   +2 more sources

Efficacy and safety of spesolimab for the management of generalized pustular psoriasis: a drug safety evaluation

, 2023
Introduction: Generalized pustular psoriasis (GPP) is a rare form of psoriasis (less of 1% of cases). Currently, GPP is recognized as a clinical entity, distinguished from plaque psoriasis.
Camela, Elisa, Luca Potestio, Luigi Fornaro, Angelo Ruggiero, Elisa Camela, Martora, Fabrizio, Fornaro, Luigi, Ruggiero, Angelo, Potestio, Luca, Matteo Megna, Fabrizio Martora, Guerriero, Luigi, Megna, Matteo, Sara Cacciapuoti, Cacciapuoti, Sara, Luigi Guerriero   +15 more
core   +1 more source

Targeting the IL-36 receptor with spesolimab mitigates residual inflammation and prevents generalized pustular psoriasis flares. [PDF]

J Clin Invest
People with generalized pustular psoriasis experience underlying skin inflammation, even in the absence of flares.
Krueger JG, Sarkar MK, Lebwohl MG, Morita A, Gordon K, Bogle R, Cole C, Coon A, Langley RG, Warren RB, Mostaghimi A, Strober B, Burden AD, Zheng M, Mangold AR, Anadkat MJ, Barker JN, Merola JF, Tsoi LC, Tang M, Becker K, Delic D, Thoma C, Gudjonsson JE.   +23 more
europepmc   +2 more sources

Successful Control of Refractory Hidradenitis Suppurativa with Spesolimab: A Case Report. [PDF]

Acta Derm Venereol
Lai Y, Hu Y, Fan X, Yue B, Ma Y.
europepmc   +4 more sources

Spesolimab for Hidradenitis Suppurativa: A Proof-of-Concept Study

SKIN The Journal of Cutaneous Medicine, 2023
Introduction: Hidradenitis suppurativa (HS) is a chronic, inflammatory disorder characterized by painful inflammatory nodules (N), abscesses (A) and draining tunnels (dT), primarily affecting intertriginous areas. Interleukin-36 (IL-36) signaling has been notably expressed within HS inflammatory lesions. To address the need for targeted therapies, this
Afsaneh Alavi, Errol Prens, Alexa Kimball, James Krueger, Sutirtha Mukhopadhyay, Hui Wang, Nathalie Ivanhoff, Ana Cristina Hernandez, Christos Zouboulis   +8 more
openaire   +1 more source

Elewski et al. Supplementary data

, 2023
Supplementary material for the manuscript "Rapid and sustained improvements in GPPGA scores with spesolimab for treatment of generalized pustular psoriasis flares in the randomized, placebo-controlled Effisayil 1 study" by Boni Elewski et al ...
Parkinson, J
core   +4 more sources

Improvement of acute phase symptoms of pemphigus foliaceus with spesolimab

JAAD Case Reports
Shohei Iida, MD, PhD, Ken Muramatsu, MD, PhD, Ayaka Mizuno, MD, Akinobu Hayashi, MD, PhD, Yuki Mizutani, MD, PhD, Hideyuki Ujiie, MD, PhD, Kazumitsu Sugiura, MD, PhD, Keiichi Yamanaka, MD, PhD   +7 more
doaj   +3 more sources

Lymphomatoid Papulosis Following Spesolimab Treatment for Generalised Pustular Psoriasis. [PDF]

Australas J Dermatol
Namba M, Matsumoto M, Saito N, Kimura A, Sagara C, Rokunohe D, Akasaka E.   +6 more
europepmc   +4 more sources

Treatment Patterns and Pathways of Systemic Drug Therapy in Patients With Plaque, Erythrodermic, and Generalized Pustular Psoriasis: A Retrospective Cohort Study in Japan

The Journal of Dermatology, EarlyView.
ABSTRACT Systemic psoriasis treatment options have rapidly expanded in Japan, including the approval of tyrosine kinase 2 and interleukin‐36 receptor inhibitors in 2022. However, contemporary real‐world treatment patterns across plaque, erythrodermic, and generalized pustular psoriasis remain incompletely characterized.
Yayoi Tada, Yoshiko Maeda, Miyuki Hasegawa, Motonobu Sakaguchi, Takamasa Hashimoto, Teruko Narusawa, Nobuyoshi Takabayashi, Tomoko Takahashi, Taisuke Kondo, Shingo Kuroda   +9 more
wiley   +1 more source