Results 31 to 40 of about 787 (175)

Successful use of spesolimab in refractory pyoderma gangrenosum. [PDF]

JAAD Case Rep
Lum A, Patel S, Aron J, Kartono F.
europepmc   +3 more sources

Spesolimab treatment for people with flares of generalized pustular psoriasis: a plain language summary of the Effisayil™ 1 study [PDF]

, 2022
What is this study about?: Spesolimab is a drug developed to treat worsening disease (known as flares) of generalized pustular psoriasis (shortened to GPP).
Vulcu, Sebastian D., Tetzlaff, Kay, Burden, A. David, Zheng, Min, Hua, Hairui, Marrakchi, Slaheddine, Thoma, Christian, Choon, Siew Eng, Rajeswari, Sushmita, Tsai, Tsen Fang, Turki, Hamida, Hall, David, Anadkat, Milan J., Morita, Akimichi, Navarini, Alexander A., Lebwohl, Mark G., Tsai, Tsen-Fang   +16 more
core   +1 more source

Real-World Safety Profile of Spesolimab in Generalized Pustular Psoriasis: Insights From Japan as Part of a Multinational Expanded Access Program (EAP). [PDF]

J Dermatol
ABSTRACT Generalized pustular psoriasis (GPP) is a heterogeneous, systemic neutrophilic inflammatory disease, characterized by chronic symptoms and recurrent flares, which can be potentially life‐threatening. Spesolimab, an interleukin‐36 receptor antagonist, has been approved to treat GPP flares in many countries including Japan.
Morita A, Tada Y, Tsunemi Y, Komine M, Kanekura T, Imafuku S, Takahashi T, Ding X, Pillai N, Saitoh M, Simoes RS, Pöntynen N, Yamanaka K.   +12 more
europepmc   +2 more sources

Correction to "Successful Treatment With Spesolimab in a Haemodialysis Patient With Acutely Flaring Generalised Pustular Psoriasis". [PDF]

JEADV Clin Pract
JEADV Clinical Practice, Volume 5, Issue 1, Page 349-349, March 2026.
europepmc   +2 more sources

Efficacy of spesolimab for the treatment of generalized pustular psoriasis flares across pre-specified patient subgroups in the Effisayil 1 study [PDF]

, 2023
Effisayil 1 was a multicentre, randomized, double‐blind, placebo‐controlled study of the anti‐interleukin (IL)‐36 receptor monoclonal antibody, spesolimab, in patients presenting with a generalized pustular psoriasis (GPP) flare.
Hu, N., Thoma, C., A. D. Burden, D. Thaçi, C. Thoma, Burden, A.D., S. E. Choon, van de Kerkhof, P., M. Zheng, M. Quaresma, Burden, A. D., N. Hu, Okubo, Y., Choon, S. E., P. van de Kerkhof, Zheng, M., Y. Okubo, Thaçi, D., Quaresma, M.   +18 more
core   +1 more source

Spesolimab, an interleukin-36 receptor monoclonal antibody, for the treatment of generalized pustular psoriasis [PDF]

, 2023
Introduction: Generalized pustular psoriasis (GPP), is a rare cutaneous and systemic inflammatory disease which is characterized by flares of widespread painful pustulation of the skin, often associated with fever and elevated inflammatory markers ...
Burden, A. David, A David Burden
core   +1 more source

Long-term control of refractory acrodermatitis continua of Hallopeau with subcutaneous spesolimab: A case report [PDF]

JAAD Case Reports
Jan Nicolai Wagner, MD, Franziska Zirkenbach, MD, Brigtte Stephan, MD, Carolin Grote, MD, Matthias Augustin, Prof. Dr med   +4 more
doaj   +2 more sources

Spesolimab in generalised pustular psoriasis flares: a profile of its use

, 2023
Declarations Funding The preparation of this review was not supported by any external funding. Authorship and Conflict of interest T. Nie is a salaried employee of Adis International Ltd/Springer Nature and declares no relevant conflicts of interest. All
Tina Nie (13262974)
core   +1 more source

Design of Effisayil™ 2: A Randomized, Double-Blind, Placebo-Controlled Study of Spesolimab in Preventing Flares in Patients with Generalized Pustular Psoriasis [PDF]

, 2022
INTRODUCTION: Generalized pustular psoriasis (GPP) is a rare autoinflammatory skin disease characterized by flares of widespread erythema with sterile pustules, and can be relapsing with recurrent flares, or persistent with intermittent flares ...
Anadkat, Milan J, Burden, A David, Hua, Harry, Burden, A. David, Zheng, Min, Marrakchi, Slaheddine, Thoma, Christian, Choon, Siew Eng, Rajeswari, Sushmita, Turki, Hamida, Anadkat, Milan J., Morita, Akimichi, Bachelez, Hervé, Tsai, Tsen-Fang   +13 more
core   +1 more source

Spesolimab for generalised pustular psoriasis. [PDF]

Aust Prescr
europepmc   +4 more sources