Results 111 to 120 of about 67,710 (307)
Advanced Materials, EarlyView.Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi +14 more
wiley +1 more source
, 2014 (A) Collective behavior in a simulation initiated with a two-dimensional "spheroid" of cells, on substrates of varying stiffness. (B) Time lapse showing a sprouting spheroid on a 10kPa substrate. Time in MCS. Panels A and B represent a 0.75×0.75 mm2 area
René F. M. van Oers (615319) +4 more
core +1 more source
Image charge inclusion in the dielectric sphere revisited [PDF]
, 2012 Van Siclen (1988 Am. J. Phys. 56 1142) reported a curious property of a dielectric sphere in the field of an external point charge: the field outside the sphere generated by the combination of the original charge exterior and the Kelvin image charge ...
Redzic, Milan +2 more
core +2 more sources
Advanced Materials, EarlyView.Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn +17 more
wiley +1 more source
Iterative Selection of DNA Nanostructures for Cellular Uptake
Advanced Materials, EarlyView.DNA nanostructures are promising cell targeting delivery vehicles for therapeutics, but the targeting behavior is not fully understood. In this study, libraries of DNA nanostructures that can be amplified and sequenced are combined with cellular uptake as a selection pressure to iteratively refine DNA structures taken up in cells to better understand ...
Anjali Rajwar +4 more
wiley +1 more source
Description of 3D spheroid quantification.
, 2014 (a–d) Representative pictures of immunolabelled spheroids at t = 0 (a) or after 48 h of culture (c) and their corresponding binarised images (b, d). (e–g) Decomposition of the binarised image into the spheroid core (e) and edging cells (f).
Gustavo Moraes (560733) +7 more
core +1 more source
Advanced Materials, EarlyView.A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen +8 more
wiley +1 more source
MicroMechanical confinement plays an important role in regulating tumor growth and invasion; however, the quantitative, time-resolved, three-dimensional evaluation of confined tumor spheroids remains technically challenging.
Yudai Oda, Masaki Miyamoto, Shogo Miyata
doaj +1 more source
Spheroid cultures and flow cytometry analyses of spheroid outgrowths.
, 2014 Day 10 spheroids in low adhesion culture plates (a), day 10 trachea spheroids plated onto culture plates after 24 hours (b), outgrowths from spheroid cultures (c). Flow cytometry analyses of spheroid outgrowths after 25 days in vitro.
Philipp Jungebluth (630705) +24 more
core +1 more source
Advanced Materials Technologies, EarlyView.A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti +4 more
wiley +1 more source